Journal articles

Fundamentals

  • Brunet MA, Brunelle M, Lucier JF, Delcourt V, Levesque M, Grenier F, Samandi S, Leblanc S, Aguilar JD, Dufour P, Jacques JF, Fournier I, Ouangraoua A, Scott MS, Boisvert FM, Roucou X OpenProt: a more comprehensive guide to explore eukaryotic coding potential and proteomes Nucleic Acids Res. 2018 Oct 9. doi: 10.1093/nar/gky936 Download PDF
  • Cizkova D, Cubinkova V, Smolek T, Murgoci AN, Danko J, Vdoviakova K, Humenik F, Cizek M, Quanico J, Fournier I, Salzet M (2018) Localized Intrathecal Delivery of Mesenchymal Stromal Cells Conditioned Medium Improves Functional Recovery in a Rat Model of Spinal Cord Injury. Int J Mol Sci. 15;19(3). pii: E870 Download PDF
  • Delcourt V, Franck J, Quanico J, Gimeno JP, Wisztorski M, Raffo Romero A, Kobeissy F, Roucou X, Salzet M, Fournier I Top-down microproteomics bridged to MALDI MS imaging reveals the molecular physiome of brain regions. Molecular & Cellular Protemics 2018 17(2):357-372 Download PDF
  • Delcourt V, Brunelle M, Roy AV, Jacques JF, Salzet M, Fournier I, Roucou X The protein coded by a short open reading frame, not by the annotated coding sequence is the main gene product of the dual-coding gene MIEF1 Mol Cell Proteomics. 2018 Sep 4. pii: mcp.RA118.000593 Download PDF
  • Delcourt V, Staskevicius A, Salzet M, Fournier I, Roucou X Small Proteins Encoded by Unannotated ORFs are Rising Stars of the Proteome, Confirming Shortcomings in Genome Annotations and Current Vision of an mRNA. Proteomics 2018, ;18(10):21700058 Download PDF
  • Delcourt V, Brunelle M, Roy AV, Jacques JF, Salzet M, Fournier I, Roucou X First evidence that a protein coded by a short ORF, not by the annotated CDS is the main gene product. Molecular and Cellular Proteomics Download PDF
  • Duhamel M, Rose M, Rodet F, Murgoci AN, Zografidou L, Régnier-Vigouroux A, Vanden Abeele F, Kobeissy F, Nataf S, Pays L, Wisztorski M, Fournier I, Salzet M, Paclitaxel Treatment and Proprotein Convertase 1/3 (PC1/3) Knockdown in Macrophages is a Promising Antiglioma Strategy as Revealed by Proteomics and Cytotoxicity Studies. Molecular and Cellular Proteomics 2018 Jun;17(6):1126-1143 Download PDF
  • Giudetti AM, Salzet M, Cassano T.Oxidative Stress in Aging Brain: Nutritional and Pharmacological Interventions for Neurodegenerative Disorders. Oxid Med Cell Longev. 11;2018:3416028 Download PDF
  • Fatou B, Saudemont P, Duhamel M, Ziskind M, Focsa C, Salzet M, Fournier I, Real time and in vivo Pharmaceutical and Environmental studies with SpiderMass instrument. 19;281:61-66 Download PDF
  • Fatou B, Quanico J, Ziskind M, Focsa C, Salzet M, Fournier I, Remote Atmospheric Pressure Infrared Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry of Proteins. Mol. Cell. Proteomics. doi: 10.1074/mcp TIR117 000582 Download PDF
  • Fournier I, Saudemont P, Quanico J, Fatou B, Minier K, Pottier M, Bouchaert E, Pascal Q, Focsa C, Ziskind M, Tierny D, Salzet M, Can real time molecular analyses change the paradigm of dog sarcoma diagnosis and classification ? Journal of Biotechnology 280, S4 doi.org/10.1016/j.jbiotec.2018.06.315
  • Mallah K, Quanico J, Kobeissy F, Zibara K, Salzet M, Fournier I Temporally and spatially-resolved microproteomics and MALDI MSI lipidomic analysis for traumatic brain injury biomarker identification Journal of Biotechnology 280, S8 doi: 10.1016/j.jbiotec.2018.06.327
  • Mallah K, Quanico J, Trede D, Kobeissy F, Zibara K, Salzet M, Fournier I, Lipid changes Associated with traumatic brain injury revealed by 3D MALDI MSI reconstruction of brain trauma. Anal Chem Download PDF
  • Mondello S, Thelin EP, Shaw G, Salzet M, Visalli C, Cizkova D, Kobeissy F, Buki A, Extracellular vesicles: pathogenetic, diagnostic and therapeutic value in traumatic brain injury. Expert Rev Proteomics. 2018, 15(5):451-461 Download PDF
  • Murgoci AN, Cizkova D, Majerova P, Petovova E, Mevecky L, Fournier I, Salzet M (2018) Brain-Cortex Microglia-Derived Exosomes: Nanoparticles for Glioma Therapy Chem PhysChem 22;19(10):1205-1214 doi: 10.1002 cphc 201701198. Epub 2018 Feb 19 Download PDF
  • Quanico J, Hauberg-Lotte L, Devaux S, Laouby Z, Meriaux C, Raffo-Romero A, Rose M, Westerheide L, Vehmeyer J, Rodet F, Maass P, Cizkova D, Zilka N, Cubinkova V, Fournier I, Salzet M 3D MALDI mass spectrometry imaging reveals specific localization of long-chain acylcarnitines within a 10-day time window of spinal cord injury Download PDF
  • Vergara D, Romano A, Stanca E, La Pesa V, Aloisi L, De Domenico S, Franck J, Cicalini I, Giudetti A, Storelli E, Pieragostino D, Fournier I, Sannino A, Salzet M, Cerri F, Quattrini A, Maffia M. (2018) Proteomic expression profile of injured rat peripheral nerves revealed biological networks and processes J Cell Physiol. 233(8):6207-6223 Download PDF
  • Salzet M, Quanico J, Cizkova D, Karnoub MA, Laouby Z, Mériaux C Shedding new light on spinal cord injury Journal of Biotechnology 280, S4
  • Saponaro C, Sergio S, Coluccia A, De Luca M, La Regina G, Mologni L, Famiglini V, Naccarato V, Bonetti D, Gautier C, Gianni S, Vergara D, Salzet M, Fournier I, Bucci C, Silvestri R, Gambacorti, Passerini C, Maffia M, Coluccia A, A novel PDZ1-domain ligand antagonist of NHERF1 overcomes the resistance to oncogenic ß-Catenin targeting in colorectal cancer cells β-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy. Oncogene Download PDF
  • Saudemont P, Quanico J, Fatou B, Tierny D, Pascal Q, Minier K, Pottier M, Focsa C, Takats Z, Ziskind M, Salzet M, Fournier I, Real-time molecular diagnosis of tumors using water-assisted laser desorption/ionization mass spectrometry technology. Cancer Cell Download PDF
  • Simeone P, Trerotola M, Franck J, Tristan C, Marchisio M, Fournier I, Salzet M, Maffia M, Vergara D The multiverse nature of epithelial to mesenchymal transition Semin Cancer Biol. 2018 Nov 16. pii: S1044-579X(18)30086-5. doi: 10.1016/j.semcancer.2018.11.004. [Epub ahead of print] Review Download PDF
  • Quanico J, Hauberg-Lotte L, Devaux S, Rose M, Meriaux C, Laouby Z, Westerheide L, Raffo Romero A, Vehmeyer J, Rodet F, Maass P, Cizkova D, Zilka N, Blaskao J, Fournier I, Salzet M, Mass Spectrometry Imaging reveals heterogeneous disruption of lipid distribution along the rostro caudal axis in rat spinal cord injury. Scl. Report (In press)
In Revision
  • Murgoci AN, Mallah K, Aboulouard S, Lefebvre C, Kobeissy F, Fournier I, Cizek M, Cizkova D, Salzet M, The origin of microglia determines the content of exosomes and biological function. (in revision)
Submitted
  • Tretola M, Tripaldi M, Sachheti A, Hvas K, Aloisi AL, Simeone P, Relli V, Guerra F, La Sorso R, Salzet M, Lattanzio R, Vergara D, A universal super-complex is activated by Trop-2 to drive malignant cancer growth. (Submitted)
  • Nelis J, Quanico J, McFeely C, Ziskind M, Gronert S, Salzet M, Fournier I, Low-Temperature Plasma Probe Parameters Influence Ionization in ex-vivo and in-vivo Mass Spectrometry Analysis. (Submitted)
  • Maulouet T, Fatou M, Salzet M, Focsa C, Fournier I, Ziskind M, Experimental investigations of the substrate-mediated laser ablation of biological tissues. (Submitted)

Clinicals

  • Bonneau C, Paintaud G, Dubot C, Desvignes C, Le Rhun E, Trédant O, Dieras V, Taillibert S, Tresca P, Turbiez I, Li J, Passot C, Mefti F, Fourme E, Gutierrez M. (2018) Phase I feasibility study for intrathecal administration of trastuzumab in patients with HER2 positive breast carcinomatous meningitis. Eur J Cancer 95:75-84 Download PDF
  • Dirven L, Armstrong TS, Blakeley JO, Brown PD, Grant R, Jalali R, Leeper H, Mendoza T, Nayak L, Reijneveld JC, Le Rhun E, Walbert T, Weller M, Wen PY, Taphoorn MJB. (2018) Working plan for the use of patient-reported outcome measures in adults with brain tumours: a Response Assessment in Neuro-Oncology (RANO) initiative. Lancet Oncol. 19(3):e173-e180 Download PDF
  • Le Rhun E, Gorlia T. Farewell to monomodality treatment in patients with WHO lower grade glioma ? Eur J Cancer. 2018 Jan;88:109-114 Download PDF
  • Wolpert F, Weller M, A.S. Berghoff AS, E. Rushing E, L.M. Füreder LM, Petyt G, Leske H, Andratschke N, Regli L, Neidert MC, Stupp R, Stahel R, Dummer R,  Frauenfelder T, Roth P, Reyns N, Kaufmann PA, Preusser M, Le Rhun E. Diagnostic value of 18F-fluordesoxyglucose positron emission tomography (FDG)-PET/CT for patients with brain metastasis from unknown primary site. Eur J Cancer ;96:64-72 Download PDF

Fundamentals


  • Delcourt V, Staskevicius A, Salzet M, Fournier I, Roucou X, Small proteins encoded by unannotated ORFs are rising stars of the proteome, confirming shortcomings in genome annotations and current vision of an mRNA Proteomics. 2017 Jun 19. doi: 10.1002/pmic.201700058 Download PDF
  • Delcourt V, Franck J, Leblanc E, Narducci F, Robin YM, Gimeno JP, Quanico J, Wisztorski M, Kobeissy F, Jacques JF, Roucou X, Salzet M, Fournier I, Combined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer EBioMedicine. 2017 Jun 3. pii: S2352-3964(17)30229-3. doi: 10.1016/j.ebiom.2017.06.001 Download PDF
  • Devaux S, Cizkova D, Mallah K, Karnoub MA, Laouby Z, Kobeissy F, Blasko J, Nataf S, Pays L, Meriaux C, Fournier I, Salzet M, RhoA inhibitor treatment at acute phase of spinal cord injury may induce neurite outgrowth and synaptogenesis Mol Cell Proteomics. 2017 Jun 28. pii: mcp.M116.064881. doi: 10.1074/mcp.M116.064881 Download PDF
  • Diologent L, Bolbach G, Focsa C, Ziskind M, Fournier I, Laser induced post-desolvation of MALDI clusters International Journal of Mass Spectrometry 416 (2017) 29–36 Download PDF
  • Drago F, Lombardi M, Prada I, Gabrielli M, Joshi P, Cojoc D, Franck J, Fournier I, Vizioli J, Verderio C, ATP Modifies the Proteome of Extracellular Vesicles Released by Microglia and Influences Their Action on Astrocytes Front Pharmacol. 2017 Dec 13;8:910. doi: 10.3389/fphar.2017.00910 Download PDF
  • Le Rhun E, Duhamel M, Wisztorski M, Gimeno JP, Zairi F, Escande D, Reyns N, Kobeissy F, Maurage CA, Salzet M, Fournier I, Evaluation of Non-Supervised MALDI Mass Spectrometry Imaging Combined to MicroProteomics for Glioma Grade III Classification Biochim Biophys Acta. 2017 Jul;1865(7):875-890. doi: 10.1016 j bbapap 2016.11.012. Epub 2016 Nov 24 Download PDF
  • Quanico J, Franck J, Wisztorski M, Salzet M, Fournier I, Integrated Mass Spectrometry Imaging and Omics Workflows on the Same Tissue Section Using Parafilm-Assisted Microdissection Biochim Biophys Acta. 2017 Jul;1861(7):1702-1714. doi: 10.1016/j.bbagen.2017.03.006. Epub 2017 Mar 11 Download PDF
  • Quanico J, Franck J, Wisztorski M, Salzet M, Fournier I, Combined MALDI Mass Spectrometry Imaging and Parafilm-Assisted Microdissection-Based LC-MS/MS Workflows in the Study of the Brain Methods Mol Biol. 2017;1598:269-283. doi: 10.1007/978-1-4939-6952-4_13
  • Quanico J, Franck J, Wisztorski M, Salzet M, Fournier I, Progress and potential of imaging mass spectrometry applied to biomarker discovery Methods Mol Biol. 2017;1598:21-43. doi: 10.1007/978-1-4939-6952-4_2
  • Quanico J, Gimeno JP, Nadal-Wollbold F, Casas C, Alvares-Georges S, Redoules D, Schmitt AM, Fournier I, Salzet M, Proteomic and transcriptomic investigation of acne vulgaris microcystic and papular lesions: Insights in the understanding of its pathophysiology Biochim Biophys Acta. 2017 Mar;1861(3):652-663. doi: 10.1016/j.bbagen.2016.10.021. Epub 2016 Oct 24 Download PDF
  • Quanico J, Franck J, Cardon T, Leblanc E, Wisztorski M, Salzet M, Fournier I, NanoLC-MS coupling of liquid microjunction microextraction for on-tissue proteomic analysis Biochim Biophys Acta. 2017 Jul;1865(7):891-900. doi: 10.1016/j.bbapap.2016.11.002. Epub 2016 Nov 9 Download PDF
  • Rizzello A, Franck J, Pellegrino M, De Nuccio F, Simeone P, Fiore G, Di Tommaso S, Malvasi A, Tinelli A, Fournier I, Salzet M, Maffia M, Vergara D, A proteomic analysis of human uterine myoma Current Protein and Peptide Science 18, 167-174
  • Samandi S, V Roy A, Delcourt V, Lucier JF, Gagnon J, C Beaudoin M, Vanderperre B, Breton MA, Jacques JF, Brunelle M, Motard J, Gagnon-Arsenault I, Fournier I, Ouangraoua A, J Hunting F, A Cohen A, R Landry C, S Scott M, Roucou X, Deep transcriptome annotation suggests that small and large proteins encoded in the same genes often cooperate BioRXIV, 2017, doi: 10.1101/142992
  • Tasiemski A, Salzet M, Neuro-immune lessons from an annelid : The medicinal leech Dev Comp Immunol. 2017 Jan;66:33-42. doi: 10.1016/j.dci.2016.06.026. Epub 2016 Jul 2 Download PDF
  • Trerotola M, Relli V, Tripaldi R, Sacchetti A, Havas K, Simeone P, Guerra E, Aloisi AL, La Sorda R, Lattanzio R, Vergara D, Fournier I, Salzet M, Piantelliand M, Alberti S, Trop-2 activates a dormant Na+/K+-ATPase/PKCα/CD9/ezrin signaling axis to override the basal growth program of cancer cells Cancer Res July 2 2017 77 (13 Supplement) 367-367; DOI:10.1158/1538-7445.AM2017-367
  • Vergara D, Stanca E, Guerra F, Priore P, Gaballo A, Franck J, Simeone P, Trerotola M, De Domenico S, Fournier I, Bucci C, Salzet M, Giudetti AM, Maffia M, β-catenin knockdown affects mitochondrial biogenesis and lipid metabolism in breast cancer cells Fontiers in Physiology ;8:544. doi: 10.3389 Download PDF
  • Wisztorski M, Quanico J, Franck J, Fatou B, Salzet M, Fournier I, Droplet-based liquid extraction for spatially-resolved microproteomics analysis of tissue sections Methods in molecular biology, pp. 49-63

Clinicals

  • Assaker R, Ritter-Lang K, Vardon D, Litrico S, Fuentes S, Putzier M, Franke J, Jarzem P, Guigui P, Nakach G, Le Huec JC, Maverick total disc replacement in a real-world patient population: a prospective, multicentre, observational study European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 26, 1417 Download PDF
  • Azais H, Ghesquiere L, Petitnicolas C, Borghesi Y, Tresch-Bruneel E, Cordoba A, Narducci F, Bresson L, Leblanc E, Pretherapeutic staging of locally advanced cervical cancer: Inframesenteric paraaortic lymphadenectomy accuracy to detect paraaortic metastases in comparison with infrarenal paraaortic lymphadenectomy Gynecologic oncology 147, 340-344 Download PDF
  • Baeesa S, Maghrab Y, Msadd, AK, Assaker R, Quality of Spine Surgery Research from the Arab Countries: A Systematic Review and Bibliometric Analysis BioMed research international 7560236 Download PDF
  • Barca A, Vacca F, Vizioli J, Drago F, Vetrugno C, Verri T, Pagliara P, Molecular and expression analysis of the Allograft inflammatory factor1 (AIF-1) in the coelomocytes of the common sea urchin Paracentrotus lividus Download PDF
  • Chamberlain M, Junck L, Brandsma D, Soffietti R, Rudà R, Raizer J, Boogerd W, Taillibert S, Groves MD, Le Rhun E, Walker J, van den Bent M, Wen PY, Jaeckle KA, Leptomeningeal metastases: a RANO proposal for response criteria. Neuro Oncol. 2017 Apr 1;19(4):484-492. doi: 10.1093/neuonc/now183 Download PDF
  • Chiannilkulchai N, Pautier P, Genestie C, Bats AS, Vacher-Lavenu MC, Devouassoux-Shisheboran M, Treilleux I, Floquet A, Croce S, Ferron G, Mery E, Pomel C, Penault-Llorca F, Lefeuvre-Plesse C, Henno S, Leblanc E, Lemaire AS, Averous G, Kurtz JE, Ray-Coquard I, Networking for ovarian rare tumors: a significant breakthrough improving disease management. Annals of oncology : official journal of the European Society for Medical Oncology 28, 1274-1279 Download PDF
  • Darmon I, Morisse MC, Coutte A, Blonski M, Le Rhun E, Taillandier L, Roufai DB, Desenclos C, Trudel S, Faivre JC, Blanchard N, Chauffert B, Boone M, Temozolomide and Bevacizumab Induction before Chemoradiotherapy in Patients with Bulky Glioblastoma and/or with Severe Neurological Impairment Journal of Cancer 8, 1417-1 Download PDF
  • Furet E, El Bouchtaoui M, Feugeas JP, Miquel C, Leboeuf C, Beytout C, Bertheau P, Le Rhun E, Bonneterre J, Janin A, Bousquet G, Increased risk of brain metastases in women with breast cancer and p16 expression in metastatic lymph-nodes. Oncotarget 8, 37332-37341 Download PDF
  • Galldiks N, Albert NL, Sommerauer M, Grosu AL, Ganswindt U, Law I, Preusser M, Le Rhun E, Vogelbaum MA, Zadeh G, Dhermain F, Weller M, Langen KJ, Tonn JC, PET Imaging in Patients with Meningioma - Report of the RANO/PET Group. Neuro-oncology
  • Kakkos A, Bresson L, Hudry D, Cousin S, Lervat C, Bogart E, Meurant JP, El Bedoui S, Decanter G, Hannebicque K, Regis C, Hamdani A, Penel N, Tresch-Bruneel E, Narducci F, Complication-related removal of totally implantable venous access port systems: Does the interval between placement and first use and the neutropenia-inducing potential of chemotherapy regimens influence their incidence? A four-year prospective study of 4045 patients. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 43, 689-695 Download PDF
  • Kuchcinski G, Le Rhun E, Cortot AB, Drumez E, Duhal R, Lalisse M, Dumont J, Lopes R, Pruvo JP, Leclerc X, Delmaire C, Dynamic contrast-enhanced MR imaging pharmacokinetic parameters as predictors of treatment response of brain metastases in patients with lung cancer. European radiology 27, 3733-3743 Download PDF
  • Le Rhun E, Bertrand N, Dumont A, Tresch E, Le Deley MC, Mailliez A, Preusser M, Weller M, Revillion F, Bonneterre J, Identification of single nucleotide polymorphisms of the PI3K-AKT-mTOR pathway as a risk factor of central nervous system metastasis in metastatic breast cancer. European journal of cancer 87:189-198 Download PDF
  • Le Rhun E, Ruda R, Devos P, Hoang-Xuan K, Brandsma D, Perez Segura P, Soffietti R, Weller M, Diagnosis and treatment patterns for patients with leptomeningeal metastasis from solid tumors across Europe Journal of neuro-oncology 133, 419-427 Download PDF
  • Le Rhun E, Taillibert S, Chamberlain MC, Neoplastic Meningitis Due to Lung, Breast, and Melanoma Metastases Cancer control : journal of the Moffitt Cancer Center 24, 22-32 Download PDF
  • Le Rhun E, Weller M, Brandsma D, Van den Bent M, de Azambuja E, Henriksson R, Boulanger T, Peters S, Watts C, Wick W, Wesseling P, Ruda R, Preusser M, Board EE, Committee EG, EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours Annals of oncology : official journal of the European Society for Medical Oncology 28, iv84-iv99 Download PDF
  • Makki M, Ayoub G, Abdul-Hameed H, Zairi F, Mansoor B, Nait-Abdelaziz M, Ouederni M, Mullins effect in polyethylene and its dependency on crystal content: A network alteration model Journal of the mechanical behavior of biomedical materials 75, 442-454 Download PDF
  • Nicolas GN, Assaker R, Saliba C, Osman DR, Koury E, Farhat MA, Azar RR, Khoury G, Foreign Body Ingestion Causing Recurrent Diverticulitis The American journal of case reports 18, 1123-1125 Download PDF
  • Pace A, Dirven L, Koekkoek JAF, Golla H, Fleming J, Ruda R, Marosi C, Le Rhun E, Grant R, Oliver K, Oberg I, Bulbeck HJ, Rooney AG, Henriksson R, Pasman HRW, Oberndorfer S, Weller M, Taphoorn MJB, European Association of Neuro-Oncology palliative care task, f European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma. The Lancet. Oncology 18, e330-e340 Download PDF
  • Paldor I, Abbadi S, Bonne N, Ye X, Rodriguez FJ, Rowshanshad D, Itzoe M, Vigilar V, Giovannini M, Brem H, Blakeley JO, Tyler BM, The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma Journal of neuro-oncology 135, 47-56 Download PDF
  • Petitnicolas C, Azais H, Ghesquiere L, Tresch-Bruneel E, Cordoba A, Narducci F, Bresson L, Leblanc E, Morbidity of Staging Inframesenteric Paraaortic Lymphadenectomy in Locally Advanced Cervical Cancer Compared With Infrarenal Lymphadenectomy International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 27, 575-580 Download PDF
  • Reich M, Girard E, Le Rhun E, Breast leptomeningeal metastasis recurrence presenting as a manic episode Palliat Support Care. 2017 Apr;15(2):272-275. doi: 10.1017/S1478951516000456. Epub 2016 Jun 27
  • Remon J, Le Rhun E, Besse B, Leptomeningeal carcinomatosis in non-small cell lung cancer patients: A continuing challenge in the personalized treatment era Cancer treatment reviews 53, 128-137 Download PDF
  • Soffietti R, Abacioglu, U, Baumert B, Combs SE, Kinhult S, Kros JM, Marosi C, Metellus P, Radbruch A, Villa Freixa SS, Brada M, Carapella CM, Preusser M, Le Rhun E, Ruda R, Tonn JC, Weber DC, Weller M, Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO) Neuro-oncology 19, 162-174 Download PDF
  • Tallet AV, Dhermain F, Le Rhun E, Noel G, Kirova YM, Combined irradiation and targeted therapy or immune checkpoint blockade in brain metastases: toxicities and efficacy Annals of oncology : official journal of the European Society for Medical Oncology Download PDF
  • Weller M, van den Bent M, Tonn JC, Stupp R, Preusser M, Cohen-Jonathan-Moyal E, Henriksson R, Le Rhun E, Balana C, Chinot O, Bendszus M, Reijneveld JC, Dhermain F, French P, Marosi C, Watts C, Oberg I, Pilkington G, Baumert BG, Taphoorn MJB, Hegi M, Westphal M, Reifenberger G, Soffietti R, Wick W, European Association for Neuro-Oncology Task Force on, G. (2017) Evidence-based management of adult patients with diffuse glioma - Authors’ reply The Lancet Oncology 18, e430-e431 Download PDF
  • Weller M, van den Bent M, Tonn JC, Stupp R, Preusser M, Cohen-Jonathan-Moyal E Henriksson R, Le Rhun E, Balana C, Chinot O, Bendszus M, Reijneveld JC, Dhermain F, French P, Marosi C, Watts C, Oberg I, Pilkington G, Baumert BG, Taphoorn MJB, Hegi M, Westphal M Reifenberger G, Soffietti R, Wick W, EANO guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas Lancet Oncol. 2017 Jun;18(6):e315-e329. doi: 10.1016/S1470-2045(17)30194-8. Epub 2017 May 5 Download PDF
  • Wick W, Gorlia T, Bendszus M, Taphoorn M, Sahm F, Harting I, Brandes AA, Taal W, Domont J, Idbaih A, Campone M, Clement PM, Stupp R, Fabbro M, Le Rhun E, Dubois F, Weller M, von Deimling A, Golfinopoulos V, Bromberg JC, Platten M, Klein M, van den Bent MJ, Lomustine and Bevacizumab in Progressive Glioblastoma The New England journal of medicine 377, 1954-1963 Download PDF
  • Zairi F, Nzokou A, Sunna T, Obaid S, Weil AG, Bojanowski M, Shedid D, Minimally invasive costotransversectomy for the resection of large thoracic dumbbell tumors Br J Neurosurg. 2017 Apr;31(2):179-183. doi: 10.1080/02688697.2016.1233317. Epub 2016 Sep 20 Download PDF
  • Zairi F, Aboukais R, LE Rhun E, Marinho P, Maurage CA, Lejeune JP, Close follow-up after discontinuation of cyproterone acetate : a possible option to defer surgery in patients with voluminous intracranial meningioma J Neurosurg Sci. 2017 Feb;61(1):98-101

Fundamentals


  • Devaux S, Cizkova D, Qunaico J, Franck J, Ntaf S, Pays L, Hauberg-Lotte L, Mass P, Hobart J.H, Kobeissy F, Merieux, C, Wisztorski M, Slovinska L, Blaska J, Cifankova V, Fournier I, Salzet M, Proteomic analysis of the spatio-temporal based molecular kinetics of acute spinal cord injury identifies a time- and segment-specific window for effective tissue repair Mol Cell Proteomics. 2016 Aug;15(8):2641-70. doi: 10.1074/mcp.M115.057794. Epub 2016 Jun 1 Download PDF
  • Duhamel M, Rodet F, Murgoci AN, Desjardins R, Gagnon H, Wisztorski M, Fournier I, Day R, Salzet M, The proprotein convertase PC1/3 regulates TLR9 trafficking and the associated signaling pathways Sci Rep. 2016 Jan 18;6:19360. doi: 10.1038/srep1936 Download PDF
  • Duhamel M, Rodet F, Murgoci A.N, Wisztorski M, Day R, Fournier I, Salzet M, Proprotein convertase 1/3 inhibited macrophages: a novel therapeutic based on drone macrophages Eupa Open Proteomic 2016, 11: 20-22 Download PDF
  • Fatou B, Saudemont P, Leblanc E, Vinatier E, Mesdag V, Wiztorski M, Focsa C, Salzet M, Ziskind M, Fournier I, SPIDERMASS: A Novel in vivo Real-Time Mass Spectrometry Based Instrument of Low Invasiveness for Guided Surgery Applications Sci Rep. 6:25919(2016) Download PDF
  • Mouilleron H, Delcourt V, Roucou X, Death of a dogma: eukaryotic mRNAs can code for more than one protein Nucleic Acids Res. 2016 Jan 8;44(1):14-23. doi: 10.1093/nar/gkv1218. Epub 2015 Nov 17 Download PDF
  • Quanico J, Franck J, Salzet M, Fournier I, On-tissue Direct Monitoring of Global Hydrogen/Deuterium Exchange by MALDI Mass Spectrometry: Tissue Deuterium Exchange Mass Spectrometry (TDXMS) Mol Cell Proteomics 2016 Oct;15(10):3321-3330. Epub 2016 Aug 10 Download PDF
  • Tissot T, Arnal A, Jacqueline C, Poulin R, Lefèvre T, Mery F, Renaud F, Roche B, Massol F, Salzet M, Ewald P, Tasiemski A, Ujvari B, Thomas F, Host manipulation by cancer cells: Expectations, facts, and therapeutic implications Bioessays 2016 Mar;38(3):276-85. doi: 10.1002/bies.201500163. Epub 2016 Feb 5 Download PDF
  • Ujvari B, Beckmann C, Biro PA, Arnal A, Tasiemski A, Massol F, Salzet M, Mery F, Boidin-Wichlacz C, Misse D, Renaud F, Vittecoq M, Tissot T, Roche B, Poulin R, Thomas F, Cancer and life-history traits: lessons from host-parasite interactions Parasitology. 2016 Apr;143(5):533-41. doi: 10.1017/S0031182016000147. Epub 2016 Feb 18 Download PDF
  • Ujvari B, Beckmann C, Arnal A, Tasiemski A, Massol F, Salzet M, Mery F, Biodin-Wichlacz C, Renaud F, Vittecoq M, Tissot T, Roche B, Poulin R, Thomas F, Cancer and life-history traits: lessons from host-parasite interactions ? Parasitology. 2016 Apr;143(5):533-41. doi: 10.1017/S0031182016000147 Download PDF
  • Vergara D, Simeone P, Frank J, Trerotola M, Tinelli A, Fournier I, Gaballo A, Saverio A, Salzet M, Maffia MD, Translating epithelial mesenchymal transition markers into the clinic: novel insights from proteomics Eupa Open Proteomic 2016, Download PDF
  • Wisztorski M, Desmons A, Quanico J, Fatou B, Gimeno JP, Franck J, Salzet M, Fournier I, Spatially-resolved protein surface microsampling from tissue sections using liquid extraction surface analysis Proteomics. 2016 Jun;16(11-12):1622-32. doi: 10.1002/pmic.201500508. Epub 2016 Apr 13 Download PDF

Clinicals

  • Aboukais R, Zairi F, Lejeune JP, Le Rhun E, Vermandel M, Blond S, Devos P, Reyns N, Response J Neurosurg 2016 Feb;124(2):584-5
  • Andrade C, Narducci F, Bresson L, Leblanc E, Boari flap ureteroneocystostomy in an oncological patient Gynecol Oncol. 2016 Oct;143(1):193. doi: 10.1016/j.ygyno.2016.07.115. PubMed PMID: 27486132 Download PDF
  • Bresson L, Allard-Duclercq C, Narducci F, Tresch E, Lesoin A, Ahmeidi A, Leblanc E, Single-port or Classic Laparoscopy Compared With Laparotomy to Assess the Peritoneal Cancer Index in Primary Advanced Epithelial Ovarian Cancer J Minim Invasive Gynecol. 2016 Jul-Aug;23(5):825-32. doi:10.1016/j.jmig.2016.03.025. PubMed PMID: 27068278
  • Frappaz D, Sunyach MP, Le Rhun E, Blonski M, Laurence V, Bonneville Levard A, Loiseau H, Meyronnet D, Callies A, Laigle-Donadey F, Faure Conter C ; au nom de l’ANOCEF, GO-AJA, de la SFCE... Adolescent and young adultes (AYAS) brain tumor national web conference. On behalf of ANOCEF, GO-AJA and SFCE societies. Bull Cancer. 2016 Nov 17. pii: S0007-4551(16)30277-6 Download PDF
  • Furtner J, Schöpf V, Seystahl K, Le Rhun E, Rudà R, Roelcke U, Koeppen S, Berghoff AS, Marosi C, Clement P, Faedi M, Watts C, Wick W, Soffietti R, Weller M, Preusser M, Kinetics of tumor size and peritumoral brain edema before, during, and after systemic therapy in recurrent WHO grade II or III meningioma Neuro Oncol. 2016 Mar;18(3):401-7 Download PDF
  • Hohnen R, Rahnama’i MS, van Gink M, van Koeveringe GA, Meriaux C, Ex vivo modulation of muscarinically induced contractions by PGE2 and an EP1 receptor antagonist in the guinea pig urinary Bladder. 2016; 3 (1) : e25
  • Kepenekian V, Elias D, Passot G, Mery E, Goere D, Delroeux D, Quenet F, Ferron G, Pezet D, Guilloit JM, Meeus P, Pocard M, Bereder JM, Abboud K, Arvieux C, Brigand C, Marchal F, Classe JM, Lorimier G, De Chaisemartin C, Guyon F, Mariani P, Ortega-Deballon P, Isaac S, Maurice C, Gilly FN, Glehen O, French Network for Rare Peritoneal Malignancies (RENAPE) Diffuse malignant peritoneal mesothelioma: Evaluation of systemic chemotherapy with comprehensive treatment through the RENAPE Database: Multi-Institutional Retrospective Study Eur J Cancer. 2016 Sep;65:69-79. doi:10.1016/j.ejca.2016.06.002 PubMed PMID:27472649 Download PDF
  • Lacorre A, Merlot B, Garabedian C, Narducci F, Chereau E, Resbeut M, Minsat M, Leblanc E, Houvenaeghel G, Lambaudie E, Early stage cervical cancer : Brachytherapy followed by type a hysterectomy versus type B radical hysterectomy alone, a retrospective evaluation Eur J Surg Oncol. 2016 Mar;42(3):376-82. doi:10.1016/j.ejso.2015.12.003. PubMed PMID: 26725307 Download PDF
  • Leblanc E, Narducci F, Bresson L, Hudry D, Fluorescence-assisted sentinel (SND) and pelvic node dissections by single-port transvaginal laparoscopic surgery, for the management of an endometrial carcinoma (EC) in an elderly obese patient Gynecol Oncol. 2016 Dec;143(3):686-687 doi:10.1016/j.ygyno.2016.10.010. PubMed PMID: 27745919 Download PDF
  • Leblanc E, Katdare N, Narducci F, Bresson L, Gouy S, Morice P, Ferron G, Querleu D, Martinez A, Should Systematic Infrarenal Para-aortic Dissection Be the Rule in the Pretherapeutic Staging of Primary or Recurrent Locally Advanced Cervix Cancer Patients With a Negative Preoperative Para-aortic PET Imaging ? Int J Gynecol Cancer. 2016 Jan;26(1):169-75. doi: 10.1097/IGC.0000000000000588 PubMed PMID: 26569062 Download PDF
  • Le Rhun E., Taillibert S., Chamberlain MC, Current Management of Adult Diffuse Infiltrative Low Grade Gliomas Curr Neurol Neurosci Rep. 2016 Feb;16(2):15. doi: 10.1007/s11910-015-0615-4 Download PDF
  • Le Rhun E, Galanis E, Leptominingeal metastases of solid cancer Curr Opin Neurol 2016 Dec;29(6):797-805 PMID:27661208 DOI:10.1097/WCO.0000000000000393 Download PDF
  • Le Rhun E, Dhermain F, Vogin G, Reyns N, Metellus P, Radionecrosis after stereotactic radiotherapy for brain metastases Expert Rev Neurother. 2016 Aug;16(8):903-14. doi: 10.1080/14737175.2016.1184572. Epub 2016 May 17
  • Le Rhun E, Taillibert S, Chamberlain MC, Systemic therapy for recurrent meningiom Expert Rev Neurother. 2016 Aug;16(8):889-901. doi: 10.1080/14737175.2016.1184087. Epub 2016 May 19
  • Le Rhun E, Perry JP, Vascular complications in glioma patients Handb Clin Neurol. 2016;134:251-66. doi: 10.1016/B978-0-12-802997-8.00015-3
  • Martinez A, Ngo C, Leblanc E, Gouy S, Luyckx M, Darai E, Classe JM, Guyon F, Pomel C, Ferron G, Filleron T, Querleu D, Surgical Complexity Impact on Survival After Complete Cytoreductive Surgery for Advanced Ovarian Cancer Ann Surg Oncol. 2016 Aug;23(8):2515-21. doi: 10.1245/s10434-015-5069-z. PubMed PMID: 27008588 Download PDF
  • Meghelli L, Narducci F, Mariette C, Piessen G, Vanseymortier M, Leblanc E, Collinet P, Duhamel A, Penel N, Reporting adverse events in cancer surgery randomized trials: A systematic review of published trials in oesophago-gastric and gynecological cancer patients Crit Rev Oncol Hematol. 2016 Aug;104:108-14.doi: 10.1016/j.critrevonc.2016.05.017. Review. PubMed PMID: 27323658 Download PDF
  • Nayama M, Collinet P, Salzet M, Vinatier D, Immunological aspects of ovarian cancer: Therapeutic perspectives J Gynecol Obstet Biol Reprod (Paris) (2016) Jun 16. pii: S0368-2315(16)30037-0 Download PDF
  • Taillibert S, Le Rhun E, Chamberlain MC, Chemotherapy-Related Neurotoxicity Curr Neurol Neurosci Rep. 2016 Sep;16(9):81. doi: 10.1007/s11910-016-0686-x Download PDF
  • Rizzello A, Franck J, Pellegrino M, De Nuccio F, Simeone P, Fiore G, Di Tommaso S, Malvasi A, Tinelli A, Fournier I, Salzet M, Maffia M, Vergara D, A proteomic analysis of human uterine myoma Curr Protein Pept Sci. 2016;18(2):167-174. doi: 10.2174/1389203717666160322150603
  • Simon N, Vasseur M, Chauffert B, Taillandier L, Le Rhun E, Systemic therapies administration for adult patients in neuro-oncology : The standards of the Association of the neuro-oncologists of French expression (ANOCEF) Bull Cancer. 2016 Apr;103(4):400-1. doi: 10.1016/j.bulcan.2016.01.011. Epub 2016 Feb 10 Download PDF
  • Vidal F, Guerby P, Luyckx M, Haddad P, Stoeckle E, Morice P, Leblanc E, Lecuru F, Daraï E, Classe JM, Pomel C, Filleron T, Ferron G, Querleu D, Rafii A, Are Early Relapses in Advanced-Stage Ovarian Cancer Doomed to a Poor Prognosis ? PLoS One. 2016 Jan 28;11(1):e0147787 doi:10.1371/journal.pone.0147787 PubMed PMID:26820579; PubMed Central PMCID: PMC4731146 Download PDF
  • Zairi F, Karnoub MA, Vieillard MH, Bouras A, Marinho P, Allaoui M, Devos P, Assaker R, Evaluation of the relevance of surgery in a retrospective case series of patients who underwent the surgical treatment of a symptomatic spine metastasis from lung cancer Eur Spine J. 2016 Dec;25(12):4052-4059. Epub 2016 Jan 28 Download PDF

Fundamentals

  • Cizkova D, Slovinska L, Grulova I, Nagyova M, Salzet M, Cikos S, Kryukov O, Cohen S, J. Tissue Eng. Reg. Med. 2015, 9: 918–929 The influence of sustained dual factor presentation on the expansion and differentiation of neural progenitors in affinity-binding alginate scaffolds Tissue Eng Regen Med. 2015 Aug;9(8):918-29. doi: 10.1002/term.1797. Epub 2013 Aug 16 Download PDF
  • Demeyer M, Wisztorski M, Decroo C, De Winter J, Caulier G, Hennebert E, Eeckhaut I, Fournier I, Flammang P, Gerbaux P, Inter- and intra-organ spatial distributions of sea star saponins by MALDI imaging Anal Bioanal Chem. 2015 Nov;407(29):8813-24. doi: 10.1007/s00216-015-9044-0. Epub 2015 Sep 28 Download PDF
  • Duhamel M, Rodet F, Delhem N, Vanden Abeele F, Kobeissy F, Nataf S, Pays L, Desjardins R, Gagnon H,Wisztorski M, Fournier I, Day R, Salzet M, Molecular Consequences of Proprotein Convertase 1/3 (PC1/3) Inhibition in Macrophages for Application to Cancer Immunotherapy: A Proteomic Study Mol Cell Proteomics. 2015 Nov;14(11):2857-77. doi: 10.1074/mcp.M115.052480. Epub 2015 Sep 1 Download PDF
  • Fatou B, Wisztorski M, Focsa C, Salzet M, Ziskind M, Fournier I, Substrate-Mediated Laser Ablation under Ambient Conditions for Spatially-Resolved Tissue Proteomics Sci Rep. 2015 Dec 17;5:18135. doi: 10.1038/srep18135 Download PDF
  • Grulova I, Slovinska L, Blaško J, Devaux S, Wisztorski M, Salzet M, Fournier I, Kryukov O, Cohen S, Cizkova D, Delivery of Alginate Scaffold Releasing Two Trophic Factors for Spinal Cord Injury Repair Sci Rep. 2015 Sep 8;5:13702. doi: 10.1038/srep13702 Download PDF
  • Ho Kim J, Franck J, Kang T, Heinsen H, Ravid R, Ferrer I, Hee Cheon M, Lee JY, Shin Yoo J, Steinbusch HW, Salzet M, Fournier I, Mok Park Y, Proteome-wide characterization of signalling interactions in the hippocampal CA4/DG subfield of patients with Alzheimer’s disease Sci Rep. 2015 Jun 10;5:11138. doi: 10.1038/srep11138 Download PDF
  • Kopp C, Wisztorski M, Revel J, Mehiri M, Dani V, Capron L, Carette D, Fournier I, Massi L, Mouajjah D, Pagnotta S, Priouzeau F, Salzet M, Meibom A, Sabourault C, NanoSIMS and MALDI-MS Imaging techniques to study cnidarian dinoflagellate symbiosis Zoology (Jena). 2015 Apr;118(2):125-31. doi: 10.1016/j.zool.2014.06.006. Epub 2014 Oct 5 Download PDF
  • Quanico J, Franck J, Gimeno J.P, Sabbagh R, Salzet M, Day R, Fournier I, Parafilm-Assisted Microdissection: A Sampling Method for Mass Spectrometry-Based Identification of Differentially Expressed Prostate Cancer Protein Biomarkers Chem Commun (Camb). 2015 Mar 18;51(22):4564-7. doi: 10.1039/c4cc08331h Download PDF
  • Rodet F., Tasiemski A., Boidin-Wichlacz C., Vuillaume C., Slomianny C., Salzet M, Hm-MyD88 and Hm-SARM: Two key regulators of the neuroimmune system and neural repair in the medicinal leech Sci Rep. 2015 Apr 16;5:9624. doi: 10.1038/srep09624 Download PDF
  • Schorn T, Drago F, Tettamanti G, Valvassori R, de Eguileor M, Vizioli J, Grimaldi A, Homolog of allograft inflammatory factor-1 induces macrophage migration during innate immune response in leech Cell Tissue Res. 2015 Mar;359(3):853-64. doi: 10.1007/s00441-014-2058-7. Epub 2014 Dec 2 Download PDF
  • Slovinska L., Szekiova E., Blasko J., Devaux S., Salzet M., Cizkova D, Comparison of dynamic behavior and maturation of neural multipotent cells derived from different spinal cord developmental stages: an in vitro study Acta Neurobiol Exp (Wars) 2015, 75(1):107-14 Download PDF
  • Tasiemski A, Massol F, Cuvillier-Hot V, Boidin-Wichlacz C, Roger E, Rodet F, Fournier I, Thomas F, Salzet M, Reciprocal immune benefit based on complementary production of antibiotics by the leech Hirudo verbana and its gut symbiont Aeromonas veronii Sci Rep. 2015 Dec 4;5:17498. doi: 10.1038/srep17498 Download PDF

Clinicals

  • Aboukais R, Assaker R, Karnoub MA, Zairi F, Delayed Hypersensitivity Reaction ; An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement Case Rep Orthop. 2015;2015:416548. doi: 10.1155/2015/416548. Epub 2015 Aug 9 Download PDF
  • Aboukais R, Zairi F, Le Rhun E, Lejeune JP, Devos P, Reyns N, Radiation-associated grade 2 meningiomas: A nine patient-series and review of the literature Clin Neurol Neurosurg. 2015 Sep;136:10-4. doi: 10.1016/j.clineuro.2015.05.022. Epub 2015 May 27 Download PDF
  • Aboukais R, Zairi F, Lejeune JP, Le Rhun E, Vermandel M, Blond S, Devos P, Reyns N, Grade 2 meningioma and radiosurgery J Neurosurg. 2015 May;122(5):1157-62 Download PDF
  • Allaoui M, Assaker R, Grelat M, Marinho P, Quidet M, Zairi F, Assessment of the surgeon radiation exposure during a minimally invasive TLIF : Comparison between fluoroscopy and O-arm system Neurochirurgie. 2015 Aug;61(4):255-9. doi: 10.1016/j.neuchi.2015.04.002. Epub 2015 Jun 10 Download PDF
  • Arsène E, Bleu G, Merlot B, Boulanger L, Vinatier D, Kerdraon O, Collinet P, Implications of a two-step procedure in surgical management of patients with early-stage endometrioid endometrial cancer J Gynecol Oncol. 2015 Apr;26(2):125-33. doi: 10.3802/jgo.2015.26.2.125 Download PDF
  • Assaker R, Vieillard MH, Zairi F, Spine metastases : are minimally invasive surgical techniques living up to the hype ? CNS Oncol. 2015;4(4):257-64. doi: 10.2217/cns.15.15. Epub 2015 Jun 22 Download PDF
  • Assaker R, Ritter-Lang K, Vardon D, Litrico S, Fuentes S, Putzier M, Franke J, Jarzem P, Guigui P, Nakach G, Le Huec JC, Maverick total disc replacement in a real-world patient population: a prospective, multicentre, observational study Eur Spine J. 2015 Sep;24(9):2047-55. doi: 10.1007/s00586-015-3918-x. Epub 2015 Jun 7 Download PDF
  • Bleu G, Arsène E, Merlot B, Kerdraon O, Bigot J, Boulanger L, Dedet B, Vinatier D, Collinet P, How to improve the preoperative staging of presumed early-stage endometrioid endometrial cancer ? Eur J Gynaecol Oncol. 2015;36(6):698-702
  • Cordoba A, Nickers P, Tresch E, Castelain B, Leblanc E, Narducci F, Le Tinier F, Lesoin A, Lacornerie T, Lartigau E, Safety of adjuvant intensity-modulated postoperative radiation therapy in endometrial cancer: Clinical data and dosimetric parameters according to the International Commission on Radiation Units (ICRU) 83 report. Rep Pract Oncol Radiother. 2015 Sep-Oct;20(5):385-92. doi: 10.1016/j.rpor.2015.06.002. PubMed PMID: 26549997; PubMed Central PMCID: PMC4597088 Download PDF
  • Cortés J, Dieras V, Ro J, Barriere J, Bachelot T, Hurvitz S, Le Rhun E, Espié M, Kim SB, Schneeweiss A, Sohn JH, Nabholtz JM, Kellokumpu-Lehtinen PL, Taguchi J, Piacentini F, Ciruelos E, Bono P, Ould-Kaci M, Roux F, Joensuu H, Afatinib alone or afatinib plus vinorelbine versus investigator’s choice of treatment for HER2-positive breast cancer with progressive brain metastases after trastuzumab, lapatinib, or both (LUX-Breast 3): a randomised, open-label, multicentre, phase 2 trial Lancet Oncol. 2015, 16(16):1700-10 Download PDF
  • Dansin E, Carnot A, Servent V, Daussay D, Robin YM, Surmei-Pintilie E, Lauridant G, Descarpentries C, Révillion F, Delattre C, EGFR-Mutated Breast Metastasis of Lung Adenocarcinoma: A Case Report Case Rep Oncol. 2015 Mar 14;8(1):164-8. doi: 10.1159/000381014. eCollection 2015 Jan-Apr Download PDF
  • Daraï E, Dubernard G, Bats AS, Heitz D, Mathevet P, Marret H, Querleu D, Golfier F, Leblanc E, Rouzier R, Ballester M, Sentinel node biopsy for the management of early stage endometrial cancer: long-term results of the SENTI-ENDO study Gynecol Oncol. 2015 Jan;136(1):54-9. doi: 10.1016/j.ygyno.2014.09.011. Epub 2014 Oct 22 Download PDF
  • Delmaire C, Savatovsky J, Boulanger T, Dhermain F, Le Rhun E, Météllus P, Gerber S, Carsin-Nicole B, Petyt G, Brain metastases imaging Cancer Radiother. 2015 Feb;19(1):16-9. doi: 10.1016/j.canrad.2014.11.008. Epub 2015 Jan 31 Download PDF
  • Demeyer M, Wisztorski M, Decroo C, De Winter J, Caulier G, Hennebert E, Eeckhaut I, Fournier I, Flammang P, Gerbaux P, Inter and intra organ spatial distributions of sea star saponins by MALDI imaging Anal Bioanal Chem. 2015 Nov;407(29):8813-24. doi: 10.1007/s00216-015-9044-0. Epub 2015 Sep 28 Download PDF
  • Franké O, Narducci F, Chereau-Ewald E, Orsoni M, Jauffret C, Leblanc E, Houvenaeghel G, Lambaudie E, Role of a Double Docking to Improve Lymph Node Dissection: When Robotically Assisted Laparoscopy for Para-aortic Lymphadenectomy Is Associated to a Pelvic Procedure Int J Gynecol Cancer. 201525(2): 331-6
  • Garabedian C, Merlot B, Bresson L, Tresch E, Narducci F, Leblanc E, Minimally Invasive Surgical Management of Early-Stage Cervical Cancer: An Analysis of the Risk Factors of Surgical Complications and of Oncologic Outcomes Int J Gynecol Cancer. 2015 May;25(4):714-21. doi: 10.1097/IGC.0000000000000390
  • Grelat M, Zairi F, Quidet M, Marinho P, Allaoui M, Assaker R, Assessment of the surgeon radiation exposure during a minimally invasive TLIF: Comparison between fluoroscopy and O-arm system Neurochirurgie. 2015 Aug;61(4):255-9. doi: 10.1016/j.neuchi.2015.04.002. Epub 2015 Jun 10 Download PDF
  • Hanssens S, Rubod C, Kerdraon O, Vinatier D, Lucot JP, Duhamel A, Collinet P, Pelvic endometriosis in women under 25: a specific management ? Minerva Med. 2015 Jun;106(3):123-31. Epub 2014 Oct 6
  • Karnoub MA, Zairi F, Aboukais R, Assaker R, Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement Case Rep Orthop. 2015;2015:416548. doi: 10.1155/2015/416548. Epub 2015 Aug 9 Download PDF
  • Le Rhun E, Chamberlain MC, Zairi F, Delmaire C, Idbaih A, Renaud F, Maurage CA, Grégoire V, Patterns of response to crizotinib in recurrent glioblastoma according to ALK and MET molecular profile in two patients CNS Oncol. 2015;4(6):381-6. doi: 10.2217/cns.15.30. Epub 2015 Oct 26 Download PDF
  • Le Rhun E, Delbeuck X, Lefeuvre-Plesse C, Kramar A, Skrobala E, Pasquier F, Bonneterre J, A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy Breast Cancer Res Treat. 2015 Aug;152(3):569-80. doi: 10.1007/s10549-015-3493-1. Epub 2015 Jul 11 Download PDF
  • Le Rhun E, Taillibert S, Chamberlain MC, Anaplastic glioma: current treatment and management Expert Rev Neurother. 2015 Jun;15(6):601-20. doi: 10.1586/14737175.2015.1042455. Epub 2015 May 2 Download PDF
  • Le Rhun E, Taillibert S, Chamberlain MC, The future of high-grade glioma: Where we are and where are we going Surg Neurol Int. 2015 Feb 13;6(Suppl 1):S9-S44. doi: 10.4103/2152-7806.151331. eCollection 2015 Download PDF
  • Le Rhun E, Taillibert S, Boulanger T, Zairi F, Bonneterre J, Chamberlain MC, Prolonged Response and Restoration of Functional Independence with Bevacizumab plus Vinorelbine as Third-Line Treatment for Breast Cancer-Related Leptomeningeal Metastases Case Rep Oncol. 2015 Feb 12;8(1):72-7. doi: 10.1159/000375293. eCollection 2015 Jan-Apr Download PDF
  • Le Rhun E, Dhermain F, Noël G, Reyns N, Carpentier A, Mandonnet E, Taillibert S, Metellus P, ANOCEF l’Association des neuro-oncologues d’expression française. ANOCEF guidelines for the management of brain metastases Cancer Radiother. 2015 Feb;19(1):66-71. doi: 10.1016/j.canrad.2014.11.006. Epub 2015 Feb 7 Download PDF
  • Le Rhun E, Mateus C, Mortier L, Dhermain F, Guillot B, Grob JJ, Lebbe C, Thomas M, Jouary T, Leccia MT, Robert C, Systemic treatment of melanoma brain metastases Cancer Radiother. 2015 Feb;19(1):48-54 Download PDF
  • Le Rhun É, Taillibert S, Blonski M, Jouniaux Delbez N, Delgadillo D, Taillia H, Auquier P, Belin C, Bonnetain F, Varin D, Tallet A, Taillandier L, Supportive care, cognition and quality of life in brain metastases Cancer Radiother. 2015 Feb;19(1):55-60. doi: 10.1016/j.canrad.2014.11.003. Epub 2015 Jan 29 Download PDF
  • Lévy C, Allouache D, Lacroix J, Dugué AE, Supiot S, Campone M, Mahe M, Kichou S, Leheurteur M, Hanzen C, Dieras V, Kirova Y, Campana F, Le Rhun E, Gras L, Bachelot T, Sunyach MP, Hrab I, Geffrelot J, Gunzer K, Constans JM, Grellard JM, Clarisse B, Paoletti X, REBECA: a phase I study of bevacizumab and whole-brain radiation therapy for the treatment of brain metastasis from solid tumours Ann Oncol. 2015 Nov;26(11):2359. doi: 10.1093/annonc/mdv386 Download PDF
  • Ligier K, Maynou C, Leroy X, Robin YM, Martin P, Clisant S, Richard F, Penel N, Improvement of the initial management of sarcomas after the dissemination of evidence-based guidelines depends on the primary sarcoma location : a population-based study BMC Cancer. 2015 Apr 2;15:218. doi: 10.1186/s12885-015-1225- Download PDF
  • Metellus P, Bialecki E, Le Rhun E, Dhermain F, Neurosurgical and radiosurgical decision making in brain metastasis patients in the area of targeted therapies ? Chin Clin Oncol. 2015 Jun;4(2):19. doi: 10.3978/j.issn.2304-3865.2015.06.02 Download PDF
  • Métellus P, Tallet A, Dhermain F, Reyns N, Carpentier A, Spano JP, Azria D, Noël G, Barlési F, Taillibert S, Le Rhun É, Global brain metastases management strategy: a multidisciplinary-based approach Cancer Radiother. 2015 Feb;19(1):61-5. doi: 10.1016/j.canrad.2014.11.009. Epub 2015 Jan 31 Download PDF
  • Sakji-Dupré L, Le Rhun E, Templier C, Desmedt E, Blanchet B, Mortier L, Cerebrospinal fluid concentrations of vemurafenib in patients treated for brain metastatic BRAF-V600 mutated melanoma Melanoma Res. 2015 Aug;25(4):302-5. doi: 10.1097/CMR.0000000000000162 Download PDF
  • Taillibert S, Le Rhun E, Chamberlain MC, Tumor treating fields: a new standard treatment for glioblastoma ? Curr Opin Neurol. 2015 Dec;28(6):659-64. doi: 10.1097/WCO.0000000000000250 Download PDF
  • Taillibert S, Le Rhun É, Epidemiology of brain metastases Cancer Radiother. 2015 Feb;19(1):3-9. doi: 10.1016/j.canrad.2014.11.001. Epub 2015 Jan 27 Download PDF
  • Taillibert S, Taillandier L, Le Rhun E, Venous thrombosis in patients with high-grade glioma Curr Opin Oncol. 2015 Nov;27(6):516-21. doi: 10.1097/CCO.0000000000000226 Download PDF
  • Taillibert S, Conforti R, Bonneterre J, Bachelot T, Le Rhun E, Bernard-Marty C, Systemic treatment of brain metastases from breast cancer Cancer Radiother. 2015 Feb;19(1):36-42. doi: 10.1016/j.canrad.2014.12.003. Epub 2015 Feb 7 Download PDF
  • Taillandier L, Le Rhun É, Métellus P, Mornex F, Mazeron JJ, Editorial Cancer Radiother. 2015 Feb;19(1):1-2. doi: 10.1016/j.canrad.2014.11.005. Epub 2015 Feb 7 Download PDF
  • Tu Q, Wu X, Le Rhun E, Blonski M, Wittwer B, Taillandier L, De Carvalho Bittencourt M, Faure GC, CellSearch(®) technology applied to the detection and quantification of tumor cells in CSF of patients with lung cancer leptomeningeal metastasis Lung Cancer. 2015 Nov;90(2):352-7. doi: 10.1016/j.lungcan.2015.09.008. Epub 2015 Sep 14 Download PDF
  • Turpin A, Sharif A, Stoven L, Blond S, Maurage CA, Le Rhun E, The stem cell niche in glioblastoma: from fundamental aspects to targeted therapies Bull Cancer. 2015 Jan;102(1):24-33. doi: 10.1016/j.bulcan.2014.07.001. Epub 2015 Jan 6 Download PDF
  • Ursu R, Taillibert S, Banissi C, Vicaut E, Bailon O, Le Rhun E, Guillamo JS, Psimaras D, Tibi A, Sacko A, Marantidou A, Belin C, Carpentier AF, Immunotherapy with CpG-ODN in neoplastic meningitis: A phase I trial Cancer Sci. 2015 Sep;106(9):1212-8. doi: 10.1111/cas.12724. Epub 2015 Jul 29 Download PDF
  • Zairi F, Vieillard MH, Assaker R, Spine metastases: are minimally invasive surgical techniques living up to the hype ? CNS Oncol. 2015;4(4):257-64. doi: 10.2217/cns.15.15. Epub 2015 Jun 22 Download PDF
  • Zairi F, Le Rhun E, Bertrand N, Boulanger T, Taillibert S, Aboukais R, Assaker R, Chamberlain MC, Complications related to the use of an intraventricular access device for the treatment of leptomeningeal metastases from solid tumor: a single centre experience in 112 patients J Neurooncol. 2015 Sep;124(2):317-23. doi: 10.1007/s11060-015-1842-x. Epub 2015 Jun 13 Download PDF

Fundamentals

  • Arafah K, Longuespée R, Desmons A, Kerdraon O, Fournier I, Salzet M
    Lipidomics for Clinical Diagnosis: Dye Assisted Laser Desorption/Ionisation (DALDI) method for lipids detection in MALDI mass spectrometry imaging OMICS 2014, 18(8): 487-98 Download PDF
  • Cizkova D, Devaux S, Le Marrec-Croq F, Franck J, Slovinska L, Blasko J, Rosocha J, Spakova T, Lefebvre C, Fournier I, Salzet M.
    Modulation properties of factors released by bone marrow stromal cells on activated microglia: an in vitro study Sci Rep. 2014 Dec 19;4:7514. doi: 10.1038/srep07514 Download PDF
  • Cizkova D, Le Marrec-Croq F, Franck J, Slovinska L, Grulova I, Devaux S, Lefebvre C, Fournier I, Salzet M
    Alterations of protein composition along the rostro-caudal axis after spinal cord injury: proteomic, in vitro and in vivo analyses Front Cell Neurosci. 2014 Apr 17;8:105. doi: 10.3389/fncel.2014.00105. eCollection 2014 Download PDF Download Supplementary data
  • Diologent L, Franck J, Wisztorski M, Treizebre A, Focsa C, Fournier I, Ziskind M
    On the Origin of Increased Sensitivity and Mass Resolution Using Silicon Masks in MALDI Anal Chem. 2014 Feb 4;86(3):1404-13. doi: 10.1021/ac401329r. Epub 2014 Jan 22 Download PDF
  • Drago F, Sautière PE, Le Marrec-Croq F, Accorsi A, Van Camp C, Salzet M, Lefebvre C, Vizioli J
    Microglia of medicinal leech (Hirudo medicinalis) express a specific activation marker homologous to Vertebrate Ionized calcium-Binding Adapter molecule 1 (Iba1/alias Aif-1) Dev Neurobiol. 2014 Oct;74(10):987-1001. doi: 10.1002/dneu.22179. Epub 2014 Apr 22 Download PDF
  • Le Marrec-Croq F, Bocquet-Garçon A, Vizioli J, Van Camp C, Drago F, Franck J, Wisztorski M, Salzet M, Sautiere PE, Lefebvre C
    Calreticulin contributes to C1q-dependent recruitment of microglia in the leech Hirudo medicinalis Med Sci Monit. 2014 Apr 19;20:644-53. doi: 10.12659/MSM.890091 Download PDF
  • Longuespée R, Tastet C, Desmons A, Kerdraon O, Day R, Fournier I, Salzet M
    HFIP extraction followed by 2D CTAB-SDS PAGE separation: A new methodology for protein identification from tissue sections after MALDI mass spectrometry profiling for personalized medicine research OMICS. 2014 Jun;18(6):374-84. doi: 10.1089/omi.2013.0176. Epub 2014 May 19 Download PDF
  • Longuespée R, Couture, F, Levesque C, Kwiakowska, Desjardins R, Gagnon S, Vergara D, Maffia M, Fournier I, Salzet M, Day R
    Implications of proprotein convertases in ovarian cancer cell proliferation and tumor progression: insights for PACE4 as a therapeutic target Transl Oncol. 2014 May 9. pii: S1936-5233(14)00043-6. doi: 10.1016/j.tranon.2014.04.008 Download PDF
  • Longuespé R, Boyon C, Desmons A, Leblanc E, Farré I, Vinatier D, Day R, Fournier I, Salzet M
    Spectroimmunohistochemistry: a novel form of MALDI mass spectrometry imaging coupled to immunohistochemistry for tracking antibodies OMICS. 2014 Feb;18(2):132-41. doi: 10.1089/omi.2013.0075. Epub 2013 Dec 19 Download PDF
  • Mériaux C, Franck J, Park DB, Quanico J, Kim YH, Chung CK, Park YM, Steinbusch H, Salzet M, Fournier I
    Human temporal lobe epilepsy analyses by tissue proteomics Hippocampus. 2014 Jun;24(6):628-42. doi: 10.1002/hipo.22246. Epub 2014 Feb 28 Download PDF

Clinicals

  • Aboukais R, Zairi F, Reyns N, Le Rhun E, Touzet G, Blond S, Lejeune JP
    Surgery followed by radiosurgery: a deliberate valuable strategy in the treatment of intracranial meningioma Clin Neurol Neurosurg. 2014 Sep;124:123-6. doi: 10.1016/j.clineuro.2014.06.035. Epub 2014 Jul 6 Download PDF
  • Boyon C, Monsarrat N, Clouqueur E, Deruelle P
    Cervical ripening: is there an advantage for a double-balloon device in labor induction ? Gynecol Obstet Fertil. 2014 Oct;42(10):674-80. doi: 10.1016/j.gyobfe.2014.07.035. Epub 2014 Sep 22 Download PDF
  • Chamberlain M, Soffietti R, Raizer J, Rudà R, Brandsma D, Boogerd W, Taillibert S, Groves MD, Le Rhun E, Junck L, van den Bent M, Wen PY, Jaeckle KA
    Leptomeningeal metastasis: a Response Assessment in Neuro-Oncology critical review of endpoints and response criteria of published randomized clinical trials Neuro Oncol. 2014 Sep;16(9):1176-85. doi: 10.1093/neuonc/nou089. Epub 2014 May 27 Download PDF
  • Italiano A1, Le Cesne A, Mendiboure J, Blay JY, Piperno-Neumann S, Chevreau C, Delcambre C, Penel N, Terrier P, Ranchere-Vince D, Lae M, Le Guellec S, Michels JJ, Robin YM, Bellera C, Bonvalot S.
    Prognostic factors and impact of adjuvant treatments on local and metastatic relapse of soft-tissue sarcoma patients in the competing risks setting Cancer. 2014 Nov 1;120(21):3361-9. doi: 10.1002/cncr.28885. Epub 2014 Jul 10 Download PDF
  • Le Guellec S, Chibon F, Ouali M, Perot G, Decouvelaere AV, Robin YM, Larousserie F, Terrier P, Coindre JM, Neuville A
    Are peripheral purely undifferentiated pleomorphic sarcomas with MDM2 amplification dedifferentiated liposarcomas ? Am J Surg Pathol. 2014 Mar;38(3):293-304. doi: 10.1097/PAS.0000000000000131 Download PDF
  • Leblanc E, Vennin P, Narducci F, Merlot B, Bresson L, Farré I, Salzet M, Bertrand O, Maillez A, Adenis C, Prophylactic Adnexectomy in Women at Hereditary Risk for Ovarian Carcinomas: towards New Tracks ? Oncologie (2014) 16: 438-444 Download PDF
  • Mesdag V, Salzet M, Vinatier D.
    Trophoblast: Conductor of the maternal immune tolerance J Gynecol Obstet Biol Reprod (Paris). 2014 Nov;43(9):657-70. doi: 10.1016/j.jgyn.2014.06.008. Epub 2014 Jul 22 Download PDF
  • Taillibert S, Le Rhun E, Chamberlain MC, Intracranial cystic lesions: a review Curr Neurol Neurosci Rep. 2014 Sep;14(9):481. doi: 10.1007/s11910-014-0481-5 Download PDF
  • Toulmonde M1, Le Cesne A, Mendiboure J, Blay JY, Piperno-Neumann S, Chevreau C, Delcambre C, Penel N, Terrier P, Ranchère-Vince D, Lae M, Le Guellec S, Michels JJ, Robin YM, Bellera C, Italiano A, Long-term recurrence of soft tissue sarcomas: prognostic factors and implications for prolonged follow-up Cancer. 2014 Oct 1;120(19):3003-6. doi: 10.1002/cncr.28836. Epub 2014 Jun 18 Download PDF
  • Zairi F, Ouammou Y, Le Rhun E, Aboukais R, Blond S, Vermandel M, Deken V, Devos P, Reyns N, Relevance of gamma knife radiosurgery alone for the treatment of non-small cell lung cancer brain metastases Clin Neurol Neurosurg. 2014 Oct;125:87-93. doi: 10.1016/j.clineuro.2014.07.030. Epub 2014 Jul 27 Download PDF

  • Arafah K, Croix D, Vizioli J, Desmons A, Fournier I, Salzet M, Involvement of Nitric oxide through encannabinoids release in microglia activation during the course of CNS regeneration in the medicinal leech Glia. 2013 Apr;61(4):636-49. doi: 10.1002/glia.22462. Epub 2013 Jan 28 Download PDF
  • Bonnel D, Franck J, Mériaux C, Salzet M, Fournier I, Ionic matrices pre-spotted MALDI plates for patients markers following, drugs titration and MALDI MSI Anal Biochem. 2013 Mar 1;434(1):187-98. doi: 10.1016/j.ab.2012.10.035. Epub 2012 Nov 7 Download PDF
  • Franck J, Quanico J, Wisztorski M, Day R, Salzet M, Fournier I, Quantification Based Mass Spectrometry Imaging of Proteins by Parafilm Assisted Microdissection Anal Chem. 2013 Sep 3;85(17):8127-34. doi: 10.1021/ac4009397. Epub 2013 Aug 12 Download PDF
  • Gagnon H, Refaie S, Gagnon S, Desjardins R, Salzet M, Day R, Proprotein convertase 1/3 (PC1/3) in the rat alveolar macrophage cell line NR8383: localization,trafficking and effects on cytokine secretion PLoS One. 2013 Apr 24;8(4):e61557. doi: 10.1371/journal.pone.0061557. Print 2013 Download PDF
  • Hanssen S, Collinet P, Leblanc E, Salzet M, Vinatier D, Immunological analogies between ovarian cancer and pregnancy J Gynecol Obstet Biol Reprod (Paris). 2013 May;42(3):217-26. doi: 10.1016/j.jgyn.2012.10.007. Epub 2012 Nov 22 Download PDF
  • Le Marrec-Croq F, Drago F, Vizioli J, Sautière PE, Lefebvre C, The leech nervous system: A valuable model to study the microglia involvement in regenerative processes Clin Dev Immunol. 2013;2013:274019. doi: 10.1155/2013/274019. Epub 2013 Jun 26 Download PDF
  • Lonsguespée R, Boyon C, Kerdraon O, Ighodaro A, Desmons A, Vinatier D, Fournier I, Day R, Salzet M, Ovarian Cancer Patient Case Studies By Maldi Mass Spectrometry Profiling: A molecular study of endometrioid and serous carcinoma origins Proteomic Clinical Applications 2013,7(5-6): 337-54 Download PDF
  • Quanico J, Franck J, Dauly C, Strupat K, Dupuy J, Day R, Salzet M, Fournier I, Wisztorski M, Development of Liquid Microjunction Extraction Strategy for Improving Protein Identification from Tissue Sections J Proteomics. 2013 Feb 21;79:200-18. doi: 10.1016/j.jprot.2012.11.025. Epub 2013 Jan 2 Download PDF Download Supplementary data
  • Vanderperre B, Lucier JF, Tremblay G, Motard J, Vanderperre S, Wisztorski M, Salzet M, Boisvert FM, Roucou X, Direct detection of alternative open reading frames translation products in human significantly expands the proteome PLosOne 2013, 8(8):e70698 Download PDF
  • Vergara D, Simeonec P, Del Bocciod P, Totob C, Pieragostinod D, Tinellie A, Aciernoa R, Albertic S, Salzet M, Giannellig G, Sacchettad P, Maffia M, Comparative proteome profiling of breast tumor cell lines by gel electrophoresis and mass spectrometry reveals an epithelial mesenchymal transition associated protein signature Mol Biosyst. 2013 Jun;9(6):1127-38. doi: 10.1039/c2mb25401h Download PDF
  • Wisztorski M, Fatou B, Franck J, Desmons A, Farré I, Leblanc E, Fournier I, Salzet M, Microproteomics by Liquid Extraction Surface Analysis: Application to FFPE tissue to study the Fimbria region of tubo-ovarian cance Proteomics Clin Appl. 2013 Apr;7(3-4):234-40. doi: 10.1002/prca.201200070. Epub 2013 Mar 6 Download PDF

  • Boidin-Wichlacz C, Vergote D, Slomianny C, Jouy N, Salzet M, Tasiemski A, Morphological and functional characterization of leech circulating blood cells: role in immunity and neural repair Cell Mol Life Sci. 2012 May;69(10):1717-31. doi: 10.1007/s00018-011-0897-x. Epub 2011 Dec 11 Download PDF
  • Brignole-Baudouin F, Desbenoit N, Hamm G, Liang H, Both JP, Brunelle A, Fournier I, Guerineau V, Legouffe R, Stauber J, Touboul D, Wisztorski M, Salzet M, Laprevote O, Baudouin C, A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits PLoS One. 2012;7(11):e50180. doi: 10.1371/journal.pone.0050180. Epub 2012 Nov 27 Download PDF
  • Gagnon H, Franck J, Wisztorski M, Day R, Fournier I, Salzet M, Targeted mass spectrometry imaging: specific targeting mass spectrometry imaging technologies from history to perspective Prog Histochem Cytochem. 2012; 47(3): 133-74 Download PDF
  • Jung S, Sönnichsen FD, Hung CW, Tholey A, Boidin-Wichlacz C, Haeusgen W, Gelhaus C, Desel C, Podschun R, Waetzig V, Tasiemski A, Leippe M, Grötzinger J, Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities J Biol Chem. 2012 Apr 20;287(17):14246-58. doi: 10.1074/jbc.M111.336495. Epub 2012 Mar 6 Download PDF
  • Longuespée R, Boyon C, Desmons A, Vinatier D, Leblanc E, Farré I, Wisztorski M, Ly K, D’Anjou F, Day R, Fournier I, Salzet M, Ovarian cancer molecular pathology Cancer Metastasis Rev. 2012 Dec;31(3-4):713-32. doi: 10.1007/s10555-012-9383-7 Download PDF
  • Longuespée R, Boyon C, Castellier C, Jacquet A, Desmons A, Kerdraon O, Vinatier D, Fournier I, Day R, Salzet M, The C-terminal fragment of the immunoproteasome PA28S (Reg alpha) as an early diagnosis and tumor-relapse biomarker: evidence from mass spectrometry profiling Histochem Cell Biol. 2012 Jul;138(1):141-54. doi: 10.1007/s00418-012-0953-0. Epub 2012 Apr 25 Download PDF
  • Ray-Coquard I, Chauvin F, Leblanc E, Caux C, Hoarau H, Bonnetain F, Christophe V, Sastre-Garau X, Lazennec G, Poulain L, Haie-Meder C, Pujade-Lauraine E, Salzet M, Deutsch E, Devouassoux M, Penault Llorca F, Lecuru F, Taieb S, Arveux P, Theillet C, Joly F, PAIR-gynaecology: multi/interdisciplinary for gynecologic cancer research. Problems needed to be resolved Bull Cancer. 2012 Apr 1;99(4):479-98. doi: 10.1684/bdc.2012.1558
  • Refaie S, Gagnon S, Gagnon H, Desjardins R, D’Anjou F, D’Orléans-Juste P, Zhu X, Steiner DF, Seidah NG, Lazure C, Salzet M, Day R, Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion J Biol Chem. 2012 Apr 27;287(18):14703-17. doi: 10.1074/jbc.M111.323220. Epub 2012 Mar 6 Download PDF
  • Tahtouh M, Garçon-Bocquet A, Croq F, Vizioli J, Sautière PE, Van Camp C, Salzet M, Nagnan-le Meillour P, Pestel J, Lefebvre C, Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis J Neuroinflammation. 2012 Feb 22;9:37. doi: 10.1186/1742-2094-9-37 Download PDF
  • Vergara D, Simeone P, Toraldo D, Del Boccio P, Vergaro V, Leporatti S, Pieragostino D, Tinelli A, De Domenico S, Alberti S, Urbani A, Salzet M, Santino A, Maffia M, Resveratrol downregulates Akt/GSK and ERK signalling pathways in OVCAR-3 ovarian cancer cells Mol Biosyst. 2012 Apr;8(4):1078-87. doi: 10.1039/c2mb05486h. Epub 2012 Jan 10 Download PDF

  • Bonnel D, Longuespee R, Franck J, Roudbaraki M, Gosset P, Day R, Salzet M, Fournier I, Multivariate analyses for biomarkers hunting and validation through on-tissue bottom-up or in-source decay in MALDI-MSI: application to prostate cancer Anal Bioanal Chem. 2011 Jul;401(1):149-65. doi: 10.1007/s00216-011-5020-5. Epub 2011 Apr 26 Download PDF
  • Bruand J, Alexandrov T, Sistla S, Wisztorski M, Meriaux C, Becker M, Salzet M, Fournier I, Macagno E, Bafna V, AMASS: algorithm for MSI analysis by semi-supervised segmentation J Proteome Res. 2011 Oct 7;10(10):4734-43. doi: 10.1021/pr2005378. Epub 2011 Aug 25 Download PDF
  • Bruand J, Sistla S, Mériaux C, Dorrestein PC, Gaasterland T, Ghassemian M, Wisztorski M, Fournier I, Salzet M, Macagno E, Bafna V, Automated querying and identification of novel peptides using MALDI mass spectrometric imaging J Proteome Res. 2011 Apr 1;10(4):1915-28. doi: 10.1021/pr101159e. Epub 2011 Mar 15 Download PDF
  • Cuvillier-Hot V, Boidin-Wichlacz C, Slomianny C, Salzet M, Tasiemski A, Characterization and immune function of two intracellular sensors, HmTLR1 and HmNLR, in the injured CNS of an invertebrate Dev Comp Immunol. 2011 Feb;35(2):214-26. doi: 10.1016/j.dci.2010.09.011. Epub 2010 Oct 29 Download PDF
  • D’Anjou F, Routhier S, Perreault JP, Latil A, Bonnel D, Fournier I, Salzet M, Day R, Molecular Validation of PACE4 as a Target in Prostate Cancer Transl Oncol. 2011 Jun;4(3):157-72. Epub 2011 Jun 1 Download PDF
  • Grimaldi A, Banfi S, Vizioli J, Tettamanti G, Noonan DM, de Eguileor M, Cytokine loaded biopolymers as a novel strategy to study stem cells during wound-healing processes Macromol Biosci. 2011 Aug 11;11(8):1008-19. doi: 10.1002/mabi.201000452. Epub 2011 Mar 11 Download PDF
  • Meriaux C, Arafah K, Tasiemski A, Wisztorski M, Bruand J, Boidin-Wichlacz C, Desmons A, Debois D, Laprévote O, Brunelle A, Gaasterland T, Macagno E, Fournier I, Salzet M, Multiple changes in peptide and lipid expression associated with regeneration in the nervous system of the medicinal leech PLoS One. 2011 Apr 22;6(4):e18359. doi: 10.1371/journal.pone.0018359 Download PDF
  • Van Dyck S, Caulier G, Todesco M, Gerbaux P, Fournier I, Wisztorski M, Flammang P, The triterpene glycosides of Holothuria forskali: usefulness and efficiency as a chemical defense mechanism against predatory fish J Exp Biol. 2011 Apr 15;214(Pt 8):1347-56. doi: 10.1242/jeb.050930 Download PDF
  • Vidal-Dupiol J, Ladrière O, Destoumieux-Garzón D, Sautière PE, Meistertzheim AL, Tambutté E, Tambutté S, Duval D, Fouré L, Adjeroud M, Mitta G, Innate immune responses of a scleractinian coral to vibriosis J Biol Chem. 2011 Jun 24;286(25):22688-98. doi: 10.1074/jbc.M110.216358. Epub 2011 May 2 Download PDF

  • Croq F, Vizioli J, Tuzova M, Tahtouh M, Sautiere PE, Van Camp C, Salzet M, Cruikshank WW, Pestel J, Lefebvre C, A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis Glia. 2010 Nov 1;58(14):1649-62. doi: 10.1002/glia.21036 Download PDF
  • van Dyck S, Flammang P, Meriaux C, Bonnel D, Salzet M, Fournier I, Wisztorski M, Localization of secondary metabolites in marine invertebrates: contribution of MALDI MSI for the study of saponins in Cuvierian tubules of H. forskali PLoS One. 2010 Nov 10;5(11):e13923. doi: 10.1371/journal.pone.0013923 Download PDF
  • El Ayed M, Bonnel D, Longuespée R, Castelier C, Franck J, Vergara D, Desmons A, Tasiemski A, Kenani A, Vinatier D, Day R, Fournier I, Salzet M, MALDI imaging mass spectrometry in ovarian cancer for tracking, identifying, and validating biomarkers Med Sci Monit. 2010 Aug;16(8):BR233-45 Download PDF
  • Franck J, Longuespée R, Wisztorski M, Van Remoortere A, Van Zeijl R, Deelder A, Salzet M, McDonnell L, Fournier I, MALDI mass spectrometry imaging of proteins exceeding 30,000 daltons Med Sci Monit. 2010 Sep;16(9):BR293-9 Download PDF
  • Franck J, Ayed ME, Wisztorski M, Salzet M, Fournier I, On tissue protein identification improvement by N-terminal peptide derivatization Methods Mol Biol. 2010;656:323-38. doi: 10.1007/978-1-60761-746-4_19 Download PDF
  • Macagno ER, Gaasterland T, Edsall L, Bafna V, Soares MB, Scheetz T, Casavant T, Da Silva C, Wincker P, Tasiemski A, Salzet M, Construction of a medicinal leech transcriptome database and its application to the identification of leech homologs of neural and innate immune genes BMC Genomics. 2010 Jun 25;11:407. doi: 10.1186/1471-2164-11-407 Download PDF
  • Meriaux C, Franck J, Wisztorski M, Salzet M, Fournier I, Liquid ionic matrixes for MALDI mass spectrometry imaging of lipids J Proteomics. 2010 Apr 18;73(6):1204-18. doi: 10.1016/j.jprot.2010.02.010. Epub 2010 Feb 24 Download PDF Download Supplementray Data
  • van Remoortere A, van Zeijl RJ, van den Oever N, Franck J, Longuespée R, Wisztorski M, Salzet M, Deelder AM, Fournier I, McDonnell LA, MALDI imaging and profiling MS of higher mass proteins from tissue J Am Soc Mass Spectrom. 2010 Nov;21(11):1922-9. doi: 10.1016/j.jasms.2010.07.011. Epub 2010 Aug 4 Download PDF
  • Sethi J, Zhao B, Cuvillier-Hot V, Boidin-Wichlacz C, Salzet M, Macagno ER, Baker MW, The receptor protein tyrosine phosphatase HmLAR1 is up-regulated in the CNS of the adult medicinal leech following injury and is required for neuronal sprouting and regeneration Mol Cell Neurosci. 2010 Dec;45(4):430-8. doi: 10.1016/j.mcn.2010.08.002. Epub 2010 Aug 12 Download PDF
  • Stauber J, Ayed ME, Wisztorski M, Salzet M, Fournier I, Specific MALDI-MSI: Tag-Mass Methods Mol Biol. 2010;656:339-61. doi: 10.1007/978-1-60761-746-4_20 Download PDF
  • Stauber J, MacAleese L, Franck J, Claude E, Snel M, Kaletas BK, Wiel IM, Wisztorski M, Fournier I, Heeren RM, On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry J Am Soc Mass Spectrom. 2010 Mar;21(3):338-47. doi: 10.1016/j.jasms.2009.09.016. Epub 2009 Sep 29 Download PDF
  • Tasiemski A, Salzet M, Leech immunity: from brain to peripheral responses Adv Exp Med Biol. 2010;708:80-104 Download PDF
  • Vergara D, Merlot B, Lucot JP, Collinet P, Vinatier D, Fournier I, Salzet M, Epithelial-mesenchymal transition in ovarian cancer Cancer Lett. 2010 May 1;291(1):59-66. doi: 10.1016/j.canlet.2009.09.017. Epub 2009 Oct 31 Download PDF
  • Wisztorski M, Franck J, Salzet M, Fournier I, MALDI direct analysis and imaging of frozen versus FFPE tissues: what strategy for which sample ? Methods Mol Biol. 2010;656:303-22. doi: 10.1007/978-1-60761-746-4_18 Download PDF

  • Abbas A, Dargent T, Croix D, Salzet M, Bocquet B, Ex-vivo detection of neural events using THz BioMEMS Med Sci Monit. 2009 Sep;15(9):MT121-5 Download PDF
  • Djidja MC, Francese S, Loadman PM, Sutton CW, Scriven P, Claude E, Snel MF, Franck J, Salzet M, Clench MR, Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections Proteomics. 2009 May;9(10):2750-63. doi: 10.1002/pmic.200800624 Download PDF
  • Franck J, Arafah K, Elayed M, Bonnel D, Vergara D, Jacquet A, Vinatier D, Wisztorski M, Day R, Fournier I, Salzet M, MALDI imaging mass spectrometry: state of the art technology in clinical proteomics Mol Cell Proteomics. 2009 Sep;8(9):2023-33. doi: 10.1074/mcp.R800016-MCP200. Epub 2009 May 18 Download PDF
  • Franck J, Arafah K, Barnes A, Wisztorski M, Salzet M, Fournier I, Improving tissue preparation for matrix-assisted laser desorption ionization mass spectrometry imaging. Part 1: using microspotting Anal Chem. 2009 Oct 1;81(19):8193-202. doi: 10.1021/ac901328p Download PDF Download Supplementary Data
  • Franck J, El Ayed M, Wisztorski M, Salzet M, Fournier I, On-tissue N-terminal peptide derivatizations for enhancing protein identification in MALDI mass spectrometric imaging strategies Anal Chem. 2009 Oct 15;81(20):8305-17. doi: 10.1021/ac901043n Download PDF Download Supplementary Data
  • Galinier R Roger E, Sautiere PE, Aumelas A, Banaigs B, Mitta G, Halocyntin and papillosin, two new antimicrobial peptides isolated from hemocytes of the solitary tunicate, Halocynthia papillosa J Pept Sci. 2009 Jan;15(1):48-55. doi: 10.1002/psc.1101 Download PDF
  • Stauber J, El Ayed M, Wisztorski M, Day R, Fournier I, Salzet M, Polymerase chain reaction and immunoassay—matrix assisted laser desorption mass spectrometry using tag-mass technology: new tools to break down quantification limits and multiplexes Anal Chem. 2009 Nov 15;81(22):9512-21. doi: 10.1021/ac901416s Download PDF
  • Schikorski D, Cuvillier-Hot V, Boidin-Wichlacz C, Slomianny C, Salzet M, Tasiemski A, Deciphering the immune function and regulation by a TLR of the cytokine EMAPII in the lesioned central nervous system using a leech model J Immunol. 2009 Dec 1;183(11):7119-28. doi: 10.4049/jimmunol.0900538. Epub 2009 Nov 16 Download PDF
  • Tahtouh M, Croq F, Vizioli J, Sautiere PE, Van Camp C, Salzet M, Daha MR, Pestel J, Lefebvre C, Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord Mol Immunol. 2009 Feb;46(4):523-31. doi: 10.1016/j.molimm.2008.07.026. Epub 2008 Oct 25 Download PDF
  • Tahtouh M, Croq F, Lefebvre C, Pestel J, Is complement good, bad, or both? New functions of the complement factors associated with inflammation mechanisms in the central nervous system Eur Cytokine Netw. 2009 Sep;20(3):95-100. doi: 10.1684/ecn.2009.0157 Download PDF

  • Fournier I, Franck J, Wisztorski M, Macagno E, Salzet M, MALDI imaging: a Review of the Current Status of the Technology Neurosci. Imaging (2008) 3(1), 19-32
  • Jardin-Mathé O, Bonnel D, Franck J, Wisztorski M, Macagno E, Fournier E, Salzet M, MITICS: Applications to Biomarkers found in FFPE Tissues from 6-OHDA treated Rats Journal of Proteomics (2008), 71(3), 332-345 Download PDF
  • Lefebvre C, Vandenbulcke F, Bocquet B, Tasiemski A, Desmons A, Verstraete M, Salzet M, Cocquerelle C, Cathepsin L and cystatin B gene expression discriminates immune coelomic cells in the leech Theromyzon tessulatum Dev Comp Immunol. (2008) 32(7): 95-807 Download PDF
  • Salome N, Tasiemski A, Dutriez I, Wigger A, Landgraf R, Viltart O, Immune challenge induces differential corticosterone and interleukin-6 responsiveness in rats bred for extremes in anxiety-related behavio Neuroscience. (2008),151(4): 1112-8 Download PDF
  • Schikorski D, Cuvillier-Hot V, Leippe M, Boidin-Wichlacz C, Slomianny C, Macagno E, Salzet M, Tasiemski A, Microbial challenge promotes the regenerative process of the injured central nervous system of the medicinal leech by inducing the synthesis of antimicrobial peptides in neurons and microglia J Immunol. (2008) 181(2): 1083-95 Download PDF
  • Stauber J, Lemaire R, Franck J, Bonnel D, Croix D, Day R, Wisztorski M, Salzet M, Fournier I, MALDI Imaging of FFPE Tissues: Application to Model Animals of Parkinson Disease for Biomarker Hunting Prot Res J.. (2008) 7(3), 969-978 Download PDF
  • Wisztorski M, Croix D, Macagno E, Fournier I, Salzet M, Molecular MALDI Imaging: An Emerging Technology for Neuroscience Studies Dev. Neurobiol. (2008) 68(6), 845-858 Download PDF
  • Wisztorski M, Salzet M, Fournier I, Tissue Imaging Using MALDI Mass Spectrometry: The New Frontier of Histopathology Proteomics Expert Review Proteomics (2008) 5(3), 413-24 Download PDF

  • Dreisewerd K, Lemaire R, Pohlentz G, Wisztorski M, Berkenkamp S, Hillenkamp F, Salzet M, Fournier I, Molecular profiling of Matrix-coated and native tissue sections by UV- and IR-MALDI-O-TOF-MS Anal. Chem. (2007) 79(6), 2463-2471 Download PDF
  • Lemaire R, Desmons A, Tabet JC, Day R, Salzet M, Fournier I, Direct Analysis and MALDI Imaging of Formalin Fixed, Paraffin Embedded Tissue Sections J. Prot. Res. (2007) 6, 1295-1305 Download PDF
  • Lemaire R, Stauber J, Wisztorski M, Van Camp C, Desmons A, Deschamps M, Proess G, Rudlof I, Woods AS, Day R, Salzet M, Fournier I, TAG-MASS: Specific Molecular Imaging of Transcriptome and Proteome by Mass Spectrometry Based on Photocleavable Tag J. Prot. Res. (2007) 6, 2057-2067 Download PDF Download Supplementary Data
  • Lemaire R, Aït Menguellet S, Stauber J, Marchaudon V, Lucot JP, Collinet P, Farine MO, Vinatier D, Day R, Ducoroy P, Salzet M, Fournier I, Specific MALDI Imaging and Profiling for Biomarker Hunting and Validation: Fragment of the 11S Proteasome Activator Complex, Reg Alpha Fragment, Is a New Potential Ovary Cancer Biomarker J. Prot Res. (2007) 6 (11), 4127-4134 Download PDF
  • Tasiemski A, Schikorski D, Le Marrec-Croq F, Pontoire-Van Camp C, Boidin-Wichlacz C, Sautière PE, Hedistin: A novel antimicrobial peptide containing bromotryptophan constitutively expressed in the NK cells-like of the marine annelid, Nereis diversicolor Dev Comp Immunol. (2007) 31(8): 749-62 Download PDF
  • Toillon RA, Lagadec C, Page A, Chopin V, Sautière PE, Ricort JM, Lemoine J, Zhang M, Hondermarck H, Le Bourhis X, Proteomics demonstration that normal breast epithelial cells can induce apoptosis of breast cancer cells through insulin-like growth factor-binding protein-3 and maspin Mol Cell Proteomics. (2007) 6(7): 1239-47 Download PDF
  • Wisztorski M, Lemaire R, Stauber J, Aït-Menguellet S, Jardin-Mathé O, Day R, Salzet M, Fournier I, Imagerie MALDI: Une Nouvelle Technologie pour Découvrira et Valider de Nouveaux Biomarqueurs Médecine Sciences. (2007) 23(hors série N°1), 31-36 Download PDF
  • Wisztorski M, Lemaire R, Stauber J, Aït Menguellet S, Croix D, Jardin Mathé O, Day R, Salzet M, Fournier I, New developments in MALDI Imaging for Pathology Proteomics Studies Curr. Pharm. Design (2007) 13(32), 3317-3324 Download PDF

  • Bouchut A, Sautiere PE, Coustau C, Mitta G, Compatibility in the Biomphalaria glabrata/Echinostoma caproni model: Potential involvement of proteins from hemocytes revealed by a proteomic approach Acta Trop. (2006) 98(3):234-46 Download PDF
  • Lansac G, Dong W, Dubois CM, Ben Larbi N, Afonso C, Fournier I, Salzet M, Day R, Lipopolysaccharide Mediated Regulation of Neuroendocrine Associated Proprotein Convertases and NeuropeptidePrecursor Processing in the Rat Spleen J .Neuroimmunol. (2006) 171(1-2), 57-71 Download PDF
  • Lemaire R, Tabet JC, Ducoroy P, Hendra JB, Salzet M, Fournier I, Solid Ionic Matrices for Direct Tissue Analysis and MALDI Imaging Anal. Chem. (2006) 78, 809-819 Download PDF
  • Lemaire R, Wisztorski M, Desmons A, Tabet JC, Day R, Salzet M, Fournier I, MALDI-MS Direct Tissue Analysis of Proteins: Improving Signal Sensitivity Using Organic Treatments Anal. Chem. (2006) 78, 7145-7153 Download PDF
  • Salzet M, Tasiemski A, Cooper E, Innate immunity in lophotrochozoans: the annelids Curr Pharm Des. (2006) 12(24): 3043-50 Download PDF
  • Stauber J, Lemaire R, Wisztorski M, Aït-Menguellet S,Lucot JP, Vinatier D, Desmons A, Deschamps M, Proess G, Rudlof I, Salzet M, Fournier I, New Developments in MALDI Imaging Mass Spectrometry for Pathological Proteomics Studies, Introduction to a Novel Concept, the Specific MALDI Imaging Mol. Cell. Proteomics (2006) 5(10), S247-S247
  • Vergote D, Macagno ER, Salzet M, Sautière PE, Proteome modifications of the medicinal leech nervous system under bacterial challenge Proteomics. (2006) 6(17): 4817-25 Download PDF

  • Brogden KA, Guthmiller JM, Salzet M, Zasloff M, The nervous system and innate immunity: the neuropeptide connection Nat Immunol. (2005) 6(6): 558-64
  • Clynen E, Schoofs L, Salzet M, Trypsin and Chymotrypsin Inhibitors in Insects and Gut Leeches: an update Medical Chemistry Reviews (2005) 3: 197-206
  • Lemaire R, Lucot JP, Collinet P, Vinatier D, Tabet JC, Salzet M, Fournier I, New Developments in Direct Analysis by MALDI Mass Spectrometry for the Study of Ovarian Cancer Mol. Cel.. Proteomics (2005) 4(8), S306-S306
  • Levoye A, Mouillac B, Rivière G, Vieau D, Salzet M, Breton C, Cloning, expression and pharmacological characterization of a vasopressin-related receptor in an annelid, the leech Theromyzon tessulatum J Endocrinol. (2005) 184(1): 277-89 Download PDF
  • Salzet M, Neuropeptide-derived antimicrobial peptides from invertebrates for biomedical applications Curr Med Chem. (2005) 12(26): 3055-61 Download PDF
  • Vergote D, Bouchut A, Sautière PE, Roger E, Galinier R, Rognon A, Coustau C, Salzet M, Mitta G, Characterisation of proteins differentially present in the plasma of Biomphalaria glabrata susceptible or resistant to Echinostoma caproni Int J Parasitol. (2005) 35(2): 215-24 Download PDF

  • d’Anjou F, Bergeron LJ, Ben Larbi N, Fournier I, Salzet M, Perreault JP, Day R, Silencing of SPC2 Expression using an Engineered Delta Ribozyme in the Mouse Beta TC-3 Endocrine Cell Line J Biol Chem. (2004) 279(14),14232-14239 Download PDF
  • Deloffre L, Sautiere PE, Huybrechts R, Hens K, Vieau D, Salzet M, Angiotensin-converting enzyme inhibition studies by natural leech inhibitors by capillary electrophoresis and competition assay Eur J Biochem. (2004) 271(11): 2101-6 Download PDF
  • Giménez-Bonafé P, Soler FM, Buesa C, Sautière PE, Ausió J, Kouach M, Kasinsky HE, Chiva M, Chromatin organization during spermiogenesis in Octopus vulgaris. II: DNA-interacting proteins Mol Reprod Dev. (2004) 68(2): 232-9 Download PDF
  • Lefebvre C, Cocquerelle C, Vandenbulcke F, Hot D, Huot L, Lemoine Y, Salzet M, Transcriptomic analysis in the leech Theromyzon tessulatum: involvement of cystatin B in innate immunity Biochem J. (2004) 380(Pt 3): 617-25 Download PDF
  • Rivière G, Michaud A, Deloffre L, Vandenbulcke F, Levoye A, Breton C, Corvol P, Salzet M, Vieau D, Characterization of the first non-insect invertebrate functional angiotensin-converting enzyme (ACE): leech TtACE resembles the N-domain of mammalian ACE Biochem J. (2004) 382(Pt 2): 565-73 Download PDF
  • Stefano GB, Salamon E, Magazine HI, Salzet M, Knauf C, Prevot V, Cyclic nitric oxide release by human, rat and invertebrate tissues: examples of physiological implications in Biomedical Significance of Nitric Oxide Med. Sci. Monitor
  • Tasiemski A, Vandenbulcke F, Mitta G, Lemoine J, Lefebvre C, Sautière PE, Salzet M, Molecular characterization of two novel antibacterial peptides inducible upon bacterial challenge in an annelid, the leech Theromyzon tessulatum J Biol Chem.( 2004) 279(30): 30973-82 Download PDF
  • Vergote D, Sautière PE, Vandenbulcke F, Vieau D, Mitta G, Macagno ER, Salzet M, Up-regulation of neurohemerythrin expression in the central nervous system of the medicinal leech, Hirudo medicinalis, following septic injury J Biol Chem. (2004) 279(42): 43828-37 Download PDF

  • Deloffre L, Salzet B, Vieau D, Andries JC, Salzet M, Antibacterial properties of hemerythrin of the sand worm Nereis diversicolor Neuro Endocrinol Lett. (2003) 24(1-2): 39-45 Download PDF
  • Fournier I, Day R, Salzet M, Direct analysis of neuropeptides by in situ MALDI-TOF mass spectrometry in the rat brain Neuroendocrinol. Lett (2003) 24, 9-14 Download PDF
  • Lefebvre C, Salzet M, Annelid neuroimmune system Curr Pharm Des. 2003; 9(2): 149-58 Download PDF
  • Salzet M, Stefano G, Chromacin-like peptide in leeches Neuro Endocrinol Lett. (2003) 24(3-4): 227-32 Download PDF
  • Salzet M, Day R, Endocrine markers of cellular immunity: defining the endocrine phenotype J Soc Biol. (2003) 197(2): 97-101
  • Salzet M, Day R, Endocrine markers of cellular immunity: defining the endocrine phenotype J.Soc Biol. (2003)197(2): 97-101
  • Sergeant N, Wattez A, Galván-valencia M, Ghestem A, David JP, Lemoine J, Sautiére PE, Dachary J, Mazat JP, Michalski JC, Velours J, Mena-López R, Delacourte A, Association of ATP synthase alpha-chain with neurofibrillary degeneration in Alzheimer’s disease Neuroscience. (2003) 117(2):293-303 Download PDF
  • Srour N, Lebel A, McMahon S, Fournier I, Fugere M, Day R, Dubois CM, TACE/ADAM-17 Maturation and Activation of Sheddase Activity Require Proprotein Convertase Activity FEBS Lett. (2003) 554, 275-283 Download PDF

  • Day R, Salzet M, The neuroendocrine phenotype, cellular plasticity, and the search for genetic switches: redefining the diffuse neuroendocrine system Neuro Endocrinol Lett. (2002) 23(5-6): 447-51 Download PDF
  • Gimenez-Bonafé P, Ribes E, Sautière P, Gonzalez A, Kasinsky H, Kouach M, Sautière PE, Ausió J, Chiva M, Chromatin condensation, cysteine-rich protamine, and establishment of disulphide interprotamine bonds during spermiogenesis of Eledone cirrhosa (Cephalopoda) Eur J Cell Biol. (2002) 81(6): 341-9 Download PDF
  • Matias I, Pochard P, Orlando P, Salzet M, Pestel J, Di Marzo V, Presence and regulation of the endocannabinoid system in human dendritic cells Eur J Biochem. (2002) 269(15): 3771-8 Download PDF
  • Salzet M, Stefano GB, Cannabinoid system in invertebrates Prostaglandins, Leukotrienes & Essential Fatty Acids (2002) 66: 353-361
  • Salzet M, Verger-Bocquet M, Cellular localization of a chromogranin B-like derived peptides in leeches Neuro Endocrinol Lett. (2002) 23(3): 209-12 Download PDF
  • Salzet M, Antimicrobial peptides are signaling molecules Trends Immunol. (2002) 23(6): 283-4 Download PDF
  • Salzet M, Stefano GB, The endocannabinoid system in invertebrates Prostaglandins Leukot Essent Fatty Acids. (2002) 66(2-3): 353-61 Download PDF
  • Salzet M, Neuroimmunology of Opioids : from Invertebrates to human Neuroendocrinol Lett. (2002) 22: 451-457
  • Salzet M, Immune cells express endocrine markers Neuroendocrinol. Lett. (2002) 23: 8-9
  • Salzet M, Immune modulation by non-classical opioid families throughout animal Placebo (2002) 3(1): 12-25 kingdom
  • Salzet M, Leech thrombin inhibitors Curr Pharm Des. (2002) 8(7): 493-503 Download PDF
  • Salzet M, Immune cells express endocrine markers Neuro Endocrinol Lett. (2002) 23(1): 8-9 Download PDF
  • Schoofs L, Clynen E, Salzet M, Trypsin and chymotrypsin inhibitors in insects and gut leeches Curr Pharm Des. (2002) 8(7): 483-91 Download PDF
  • Stefano GB, Salzet M, Magazine HI, Cyclic nitric oxide release by human granulocytes, and invertebrate ganglia and immunocytes: nano-technological enhancement of amperometric nitric oxide determination Med Sci Monit. (2002) 8(6): BR199-204 Download PDF
  • Stefano GB, Magazine HI, Salzet M, Cyclic nitric oxide release by human granulocytes, and invertebrate gangliaand immunocytes: nano-technological enhancement of amperometric nitric oxide determination Med Sci Monit (2002) 8(6): 199-204
  • Tasiemski A, Hammad H, Vandenbulcke F, Breton C, Bilfinger TJ, Pestel J, Salzet M, Presence of chromogranin-derived antimicrobial peptides in plasma during coronary artery bypass surgery and evidence of an immune origin of these peptides Blood. (2002) 100(2): 553-9 Download PDF
  • Vizioli J, Salzet M, Antimicrobial peptides versus parasitic infections ? Trends Parasitol. (2002) 18(11): 475-6 Download PDF
  • Vizioli J, Salzet M, Antimicrobial peptides from animals: focus on invertebrates Trends Pharmacol Sci. (2002) 23(11): 494-6 Download PDF