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Fundamentals


Fundamentals


  • Stadler C, Gramatzki D, Le Rhun E, Hottinger AF, Hundsberger T, Roelcke U, Läubli H, Hofer S, Seystahl K, Wirsching HG, Weller M, Roth P. Glioblastoma in the oldest old: Clinical characteristics, therapy, and outcome in patients aged 80 years and older. Neurooncol Pract. 2023 Oct 20;11(2):132-141.
  • Cappe B, Vadi M, Sack E, Wacheul L, Verstraeten B, Dufour S, Franck J, Xie W, Impens F, Hendrix A, Lafontaine DLJ, Vandenabeele P, Riquet FB. Systematic compositional analysis of exosomal extracellular vesicles produced by cells undergoing apoptosis, necroptosis and ferroptosis.J Extracell Vesicles. 2023 Oct;12(10):e12365. https://doi.org/10.1002/jev2.12365

  • Ledoux L, Zirem Y, Renaud F, Duponchel L, Salzet M, Ogrinc N, Fournier I. Comparing MS imaging of lipids by WALDI and MALDI: two technologies for evaluating a common ground truth in MS imaging.Analyst. 2023 Oct 5;148(20):4982-4986.https://doi.org/10.1039/d3an01096a

  • Wisztorski M, Aboulouard S, Roussel L, Duhamel M, Saudemont P, Cardon T, Narducci F, Robin YM, Lemaire AS, Bertin D, Hajjaji N, Kobeissy F, Leblanc E, Fournier I, Salzet M. Fallopian tube lesions as potential precursors of early ovarian cancer: a comprehensive proteomic analysis. Cell Death Dis. 2023 Sep 30;14(9):644. https://doi.org/10.1038/s41419-023-06165-5

  • Diamantis D, Tsiailanis AD, Papaemmanouil C, Nika MC, Kanaki Z, Golic Grdadolnik S, Babic A, Tzakos EP, Fournier I, Salzet M, Kushwaha PP, Thomaidis NS, Rampias T, Shankar E, Karakurt S, Gupta S, Tzakos AG. Development of a novel apigenin prodrug programmed for alkaline-phosphatase instructed self-inhibition to combat cancer. J Biomol Struct Dyn. 2023 Aug 28:1-22. https://doi.org/10.1080/07391102.2023.2247083

  • Seddiki K, Precioso FE, Sanabria M, Salzet M, Fournier I, Droit A. Early Diagnosis: End-to-End CNN-LSTM Models for Mass Spectrometry Data Classification. Anal Chem. 2023 Aug 25. https://doi.org/10.1021/acs.analchem.3c00613.

  • Capuz A, Osien S, Cardon T, Karnoub MA, Aboulouard S, Raffo-Romero A, Duhamel M, Cizkova D, Trerotola M, Devos D, Kobeissy F, Van den Abelle F, Bonnefond A, Fournier I, Rodet F, Salzet M. Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome. Cell Death Dis. 2023 Aug 16;14(8):526. https://doi.org/10.1038/s41419-023-06037-y.

  • Ogrinc N, Chaillou P, Kruszewski A, Duriez C, Salzet M, Fournier I. Ambient Mass Spectrometry Imaging by Water-Assisted Laser Desorption/Ionization for Ex Vivo and in Vivo Applications. Methods Mol Biol. 2023;2688:83-94. https://doi.org/10.1007/978-1-0716-3319-9_8.

  • de Moura A, Vuagnat P, Renouf B, Pierga JY, Loirat D, Vaflard P, Lafayolle de la Bruyère C, Chaumard-Billotey N, Hajjaji N, Ladoire S, Dabakuyo S, Patsouris A, Frenel JS, Nicolai V, Alexandre M, Dohollou N, Grenier J, Bourien H, Bidard FC. Atezolizumab and paclitaxel as first line therapy in advanced triple-negative breast cancer patients included in the French early access program. Sci Rep. 2023 Aug 18;13(1):13427. https://doi.org/10.1038/s41598-023-40569-9.

  • Pasquier D, Bidaut L, Oprea-Lager DE, deSouza NM, Krug D, Collette L, Kunz W, Belkacemi Y, Bau MG, Caramella C, De Geus-Oei LF, De Caluwé A, Deroose C, Gheysens O, Herrmann K, Kindts I, Kontos M, Kümmel S, Linderholm B, Lopci E, Meattini I, Smeets A, Kaidar-Person O, Poortmans P, Tsoutsou P, Hajjaji N, Russell N, Senkus E, Talbot JN, Umutlu L, Vandecaveye V, Verhoeff JJC, van Oordt WMH, Zacho HD, Cardoso F, Fournier L, Van Duijnhoven F, Lecouvet FE. Designing clinical trials based on modern imaging and metastasis-directed treatments in patients with oligometastatic breast cancer: a consensus recommendation from the EORTC Imaging and Breast Cancer Groups. Lancet Oncol. 2023 Aug;24(8):e331-e343. https://doi.org/10.1016/S1470-2045(23)00286-3.

  • Hertler C, Felsberg J, Gramatzki D, Le Rhun E, Clarke J, Soffietti R, Wick W, Chinot O, Ducray F, Roth P, McDonald K, Hau P, Hottinger AF, Reijneveld J, Schnell O, Marosi C, Glantz M, Darlix A, Lombardi G, Krex D, Glas M, Reardon DA, van den Bent M, Lefranc F, Herrlinger U, Razis E, Carpentier AF, Phillips S, Rudà R, Wick A, Tabouret E, Meyronet D, Maurage CA, Rushing E, Rapkins R, Bumes E, Hegi M, Weyerbrock A, Aregawi D, Gonzalez-Gomez C, Pellerino A, Klein M, Preusser M, Bendszus M, Golfinopoulos V, von Deimling A, Gorlia T, Wen PY, Reifenberger G, Weller M. Long-term survival with IDH wildtype glioblastoma: first results from the ETERNITY Brain Tumor Funders' Collaborative Consortium (EORTC 1419). Eur J Cancer. 2023 Aug;189:112913. https://doi.org/10.1016/j.ejca.2023.05.002.

  • Hequet D, Hajjaji N, Charafe-Jauffret E, Boucrauta A, Dalenc F, Nicolai V, Lopez J, Tredan O, Deluche E, Fermeaux V, Tixier L, Cayre A, Menet E, Lerebours F, Rouzier R. Compliance to genomic test recommendations to guide adjuvant chemotherapy decision-making in the case of hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer, in real-life settings. Cancer Med. 2023 Jul 6. https://doi.org/10.1002/cam4.6315.

  • Lefebvre M, Duchatelet M, El Hajj H, De Courrèges A, Wallet J, Bellier C, Le Tinier F, Le Deley MC, Martinez Gomez C, Leblanc E, Narducci F, Hudry D.Stage I Clear Cell and Serous Uterine Carcinoma: What Is the Right Adjuvant Therapy? Curr Oncol. 2023 Jan 14;30(1):1174-1185. https://doi.org/110.3390/curroncol30010090.

  • Hudry D, Le Guellec S, Meignan S, Bécourt S, Pasquesoone C, El Hajj H, Martínez-Gómez C, Leblanc É, Narducci F, Ladoire S.Tumor-Infiltrating Lymphocytes (TILs) in Epithelial Ovarian Cancer: Heterogeneity, Prognostic Impact, and Relationship with Immune Checkpoints.Cancers (Basel). 2022 Oct 29;14(21):5332. https://doi.org/10.3390/cancers14215332.

  • Durand MA, Drouin A, Mouchard A, Durand L, Esnault C, Berthon P, Tallet A, Le Corre Y, Hainaut-Wierzbicka E, Blom A, Saiag P, Beneton N, Bens G, Nardin C, Aubin F, Dinulescu M, Collin C, Fromont-Hankard G, Cribier B, Laurent-Roussel S, Cokelaere K, Houben R, Schrama D, Peixoto P, Hervouet E, Bachiri K, Kantar D, Coyaud E, Guyétant S, Samimi M, Touzé A, Kervarrec T. Distinct Regulation of EZH2 and its Repressive H3K27me3 Mark in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma. J Invest Dermatol. 2023 Apr 8:S0022-202X(23)01973-5. https://doi.org/10.1016/j.jid.2023.02.038.

  • Berlanga P, Ndounga-Diakou LA, Aerts I, Corradini N, Ducassou S, Strullu M, de Carli E, André N, Entz-Werle N, Raimbault S, Roumy M, Renouard M, Gueguen G, Plantaz D, Reguerre Y, Cleirec M, Petit A, Puiseux C, Andry L, Klein S, Bodet D, Kanold J, Briandet C, Halfon-Domenech C, Nelken B, Piguet C, Saumet L, Chastagner P, Benadiba J, Millot F, Pluchart C, Schneider P, Thouvenin S, Gambart M, Serre J, Abbou S, Leruste A, Cayzac H, Gandemer V, Laghouati S, Vassal G. Measuring Safety and Outcomes for the Use of Compassionate and Off-Label Therapies for Children, Adolescents, and Young Adults With Cancer in the SACHA-France Study.JAMANetw Open. 2023 Jul 3;6(7):e2321568. https://doi.org/10.1001/jamanetworkopen.2023.21568.

  • Ogrinc N, Chaillou P, Kruszewski A, Duriez C, Salzet M, Fournier I. Ambient Mass Spectrometry Imaging by Water-Assisted Laser Desorption/Ionization for Ex Vivo and in Vivo Applications. Methods Mol Biol. 2023;2688:83-94. https://doi.org/10.1007/978-1-0716-3319-9_8

  • Garcia-Del Rio DF, Fournier I, Cardon T, Salzet M. Protocol to identify human subcellular alternative protein interactions using cross-linking mass spectrometry. STAR Protoc. 2023 Jun 28;4(3):102380.https://doi.org/10.1016/j.xpro.2023.102380

  • Capuz A, Osien S, Karnoub MA, Aboulouard S, Laurent E, Coyaud E, Raffo-Romero A, Duhamel M, Bonnefond A, Derhourhi M, Trerotola M, El Yazidi-Belkoura I, Devos D, Zilkova M, Kobeissy F, Vanden Abeele F, Fournier I, Cizkova D, Rodet F, Salzet M. Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion. Cell Death Dis. 2023 Apr 4;14(4):237.https://doi.org/10.1038/s41419-023-05737-9

  • Lewis M, Terré B, Knobel PA, Cheng T, Lu H, Attolini CS, Smak J, Coyaud E, Garcia-Cao I, Sharma S, Vineethakumari C, Querol J, Gil-Gómez G, Piergiovanni G, Costanzo V, Peiró S, Raught B, Zhao H, Salvatella X, Roy S, Mahjoub MR, Stracker TH. GEMC1 and MCIDAS interactions with SWI/SNF complexes regulate the multiciliated cell-specific transcriptional program. Cell Death Dis. 2023 Mar 17;14(3):201. https://doi.org/10.1038/s41419-023-05720-4

  • Durand MA, Drouin A, Mouchard A, Durand L, Esnault C, Berthon P, Tallet A, Le Corre Y, Hainaut-Wierzbicka E, Blom A, Saiag P, Beneton N, Bens G, Nardin C, Aubin F, Dinulescu M, Collin C, Fromont-Hankard G, Cribier B, Laurent-Roussel S, Cokelaere K, Houben R, Schrama D, Peixoto P, Hervouet E, Bachiri K, Kantar D, Coyaud E, Guyétant S, Samimi M, Touzé A, Kervarrec T. Distinct Regulation of EZH2 and its Repressive H3K27me3 Mark in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma. J Invest Dermatol. 2023 Apr 8:S0022-202X(23)01973-5. https://doi.org/10.1016/j.jid.2023.02.038

  • Gery Laurent, Franck Craynest, Maxime Thobois, and Nawale Hajjaji. Automatic Classification of Tumor Response From Radiology Reports With Rule-Based Natural Language Processing Integrated Into the Clinical Oncology Workflow. JCO Clinical Cancer Informatics, 2023, vol. 7, p. e2200139. https://doi.org/10.1200/cci.22.00139

  • Folon Lise , Baron Morgane ,Toussaint Bénédicte , Vaillant Emmanuel , Boissel Mathilde , Scherrer Victoria , Loiselle Hélène , Leloire Audrey , Badreddine Alaa , Balkau Beverley , Charpentier Guillaume , Franc Sylvia , Marre Michel , Aboulouard Soulaimane , Salzet Michel , Canouil Mickaël , Derhourhi Mehdi , Froguel Philippe , Bonnefond Amélie. Contribution of heterozygous PCSK1 variants to obesity and implications for precision medicine: a case-control study. The Lancet Diabetes & Endocrinology, 2023, vol. 11, no 3, p. 182-190. https://doi.org/10.1016/S2213-8587(22)00392-8

  • Diego Fernando Garcia-del Rio, Tristan Cardon, Sven Eyckerman, Isabelle Fournier, Amelie Bonnefond, Kris Gevaert, Michel Salzet. Employing non-targeted interactomics approach and subcellular fractionation to increase our understanding of the ghost proteome. iScience, 2023, p. 105943. https://doi.org/10.1016/j.isci.2023.105943

  • Antonella Raffo-Romero, Soulaimane Aboulouard, Emmanuel Bouchaert, Agata Rybicka, Dominique Tierny, Nawale Hajjaji, Isabelle Fournier, Michel Salzet & Marie Duhamel. Establishment and characterization of canine mammary tumoroids for translational research, BMC Biology volume 21, Article number: 23 (2023). https://doi.org/10.1186/s12915-023-01516-2

  • LEBLANC, Eric, NARDUCCI, Fabrice, FERRON, Gwenaël, MAILLIEZ, Audrey, CHARVOLIN, Jean-Yves, HAJJ, Houssein El, GUYON, Frédéric, FOURCHOTTE, Virginie, LAMBAUDIE, Eric, CROUZET, Agathe, FOUCHE, Yves, GOUY, Sébastien, COLLINET, Pierre, CAQUANT, Frédéric, POMEL, Christophe, GOLFIER, François, VAINI-COWEN, Véronique, FOURNIER, Isabelle, SALZET, Michel, TRESCH, Emmanuelle, PROBST, Alicia, LEMAIRE, Anne-Sophie, DELEY, Marie-Cécile Le and HUDRY, Delphine. Prophylactic Radical Fimbriectomy with Delayed Oophorectomy in Women with a High Risk of Developing an Ovarian Carcinoma: Results of a Prospective National Pilot Study. Cancers [online]. 10 February 2023. Vol. 15, no. 4, p. 1141. DOI 10.3390/cancers15041141. Available from: http://dx.doi.org/10.3390/cancers15041141

  • Andreas Bikfalvi, Cristine Alves da Costa, Tony Avril, Jean-Vianney Barnier, Luc Bauchet, Lucie Brisson, Pierre Francois Cartron, Hélène Castel, Eric Chevet, Hervé Chneiweiss, Anne Clavreul, Bruno Constantin, Valérie Coronas, Thomas Daubon, Monique Dontenwill, Francois Ducray, Natacha Enz-Werle, Dominique Figarella-Branger, Isabelle Fournier, Jean-Sébastien Frenel, Mathieu Gabut, Thierry Galli, Julie Gavard, Gilles Huberfeld, Jean-Philippe Hugnot, Ahmed Idbaih, Marie-Pierre Junier, Thomas Mathivet, Philippe Menei, David Meyronet, Céline Mirjolet, Fabrice Morin, Jean Mosser, Elisabeth Cohen-Jonathan Moyal, Véronique Rousseau, Michel Salzet, Marc Sanson, Giorgio Seano, Emeline Tabouret, Aurélie Tchoghandjian, Laurent Turchi, Francois M. Vallette, Somya Vats, Maité Verreault, Thierry Virolle
    Challenges in glioblastoma research: focus on the tumor microenvironment, Trends in Cancer, 2022. https://doi.org/10.1016/j.trecan.2022.09.005

Fundamentals

  • Grellety T, Hajjaji N, Petit T, Bailleux C. Stratégies pour la prise en charge des cancers du sein métastatiques récepteurs hormonaux positifs hormonorésistants [Therapeutic strategies for the treatment of endocrine resistant hormone receptor positive advanced breast cancer]. Bull Cancer. 2023 Jan;110(1):69-87. French. doi: 10.1016/j.bulcan.2022.09.007. Epub 2022 Oct 25. PMID: 36307325. https://doi.org/10.1016/j.bulcan.2022.09.007
  • Hudry D, Bécourt S, Scambia G, Fagotti A. Primary or Interval Debulking Surgery in Advanced Ovarian Cancer: a Personalized Decision-a Literature Review. Curr Oncol Rep. 2022 Dec;24(12):1661-1668. doi: 10.1007/s11912-022-01318-9. Epub 2022 Aug 15. PMID: 35969358. https://doi.org/10.1007/s11912-022-01318-9
  • Hudry D, Le Guellec S, Meignan S, Bécourt S, Pasquesoone C, El Hajj H, Martínez-Gómez C, Leblanc É, Narducci F, Ladoire S. Tumor-Infiltrating Lymphocytes (TILs) in Epithelial Ovarian Cancer: Heterogeneity, Prognostic Impact, and Relationship with Immune Checkpoints. Cancers (Basel). 2022 Oct 29;14(21):5332. doi: 10.3390/cancers14215332. PMID: 36358750; PMCID: PMC9656626. https://doi.org/10.3390/cancers14215332
  • Lefebvre M, Duchatelet M, El Hajj H, De Courrèges A, Wallet J, Bellier C, Le Tinier F, Le Deley MC, Martinez Gomez C, Leblanc E, Narducci F, Hudry D. Stage I Clear Cell and Serous Uterine Carcinoma: What Is the Right Adjuvant Therapy? Curr Oncol. 2023 Jan 14;30(1):1174-1185. doi: 10.3390/curroncol30010090. PMID: 36661739; PMCID: PMC9858549. https://doi.org/10.3390/curroncol30010090
  • Hajjaji N, Lepoutre K, Lakhdar S, Bécourt S, Bellier C, Kaczmarek E, Broyelle A, Giscard S, Lartigau E. 16 Months Follow Up of Patients' Behavior and Mild COVID-19 Patterns in a Large Cohort of Cancer Patients During the Pandemic. Front Oncol. 2022 Jun 7;12:901426. doi: 10.3389/fonc.2022.901426. PMID: 35747798; PMCID: PMC9209649. https://doi.org/10.3389/fonc.2022.901426
  • Andre F, Filleron T, Kamal M, Mosele F, Arnedos M, Dalenc F, Sablin MP, Campone M, Bonnefoi H, Lefeuvre-Plesse C, Jacot W, Coussy F, Ferrero JM, Emile G, Mouret-Reynier MA, Thery JC, Isambert N, Mege A, Barthelemy P, You B, Hajjaji N, Lacroix L, Rouleau E, Tran-Dien A, Boyault S, Attignon V, Gestraud P, Servant N, Le Tourneau C, Cherif LL, Soubeyran I, Montemurro F, Morel A, Lusque A, Jimenez M, Jacquet A, Gonçalves A, Bachelot T, Bieche I. Genomics to select treatment for patients with metastatic breast cancer. Nature. 2022 Oct;610(7931):343-348. doi: 10.1038/s41586-022-05068-3. Epub 2022 Sep 7. PMID: 36071165. https://doi.org/10.1038/s41586-022-05068-3
  • Parisi MG, Baranzini N, Dara M, La Corte C, Vizioli J, Cammarata M. AIF-1 and RNASET2 are involved in the inflammatory response in the Mediterranean mussel Mytilus galloprovincialis following Vibrio infection Fish & Shellfish Immunology, 2022, vol. 127, p. 109-118. https://doi.org/10.1016/j.fsi.2022.06.010
  • Robert Siddaway, Laura Canty, Sanja Pajovic, Scott Milos, Etienne Coyaud, Stefanie-Grace Sbergio, Arun Kumaran Vadivel Anguraj, Evan Lubanszky, Hwa Young Yun, Alessia Portante, Sheyenne Carette, Cunjie Zhang, Michael F. Moran, Brian Raught, Eric I. Campos & Cynthia Hawkins Oncohistone interactome profiling uncovers contrasting oncogenic mechanisms and identifies potential therapeutic targets in high grade glioma Acta Neuropathologica, 2022, vol. 144, no 5, p. 1027-1048. https://doi.org/10.1007/s00401-022-02489-2
  • Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins The in vivo Interaction Landscape of Histones H3.1 and H3.3. Molecular & Cellular Proteomics, 2022, vol. 21, no 10. https://doi.org/10.1016/j.mcpro.2022.100411
  • Duhamel M, Drelich L, Wisztorski M, Aboulouard S, Gimeno JP, Ogrinc N, Devos P, Cardon T, Weller M, Escande F, Zairi F, Maurage CA, Le Rhun É, Fournier I, Salzet M. Spatial analysis of the glioblastoma proteome reveals specific molecular signatures and markers of survival. Nat Commun. 2022 Nov 4;13(1):6665. https://doi.org/10.1038/s41467-022-34208-6
  • Tarbouriech, Nicolas, Florian Chenavier, Junna Kawasaki, Kamel Bachiri, Jean-Marie Bourhis, Pierre Legrand, Lily L. Freslon, Estelle M. N. Laurent, Elsa Suberbielle, Rob W. H. Ruigrok, Keizo Tomonaga, Daniel Gonzalez-Dunia, Masayuki Horie, Etienne Coyaud, and Thibaut Crépin. 2022. "Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing" Viruses 14, no. 11: 2358. https://doi.org/10.3390/v14112358
  • Lukas Leiendecker, Tobias Neumann, Pauline S. Jung, Shona M. Cronin, Thomas L. Steinacker, Alexander Schleiffer, Michael Schutzbier, Karl Mechtler, Thibault Kervarrec, Estelle Laurent, Kamel Bachiri, Etienne Coyaud, Rajmohan Murali, Klaus J. Busam, Babak Itzinger-Monshi, Reinhard Kirnbauer, Lorenzo Cerroni, Eduardo Calonje, Arno Rutten, Frank Stubenrauch, Klaus G. Griewank, Thomas Wiesner, Anna C. Obenauf; Human papillomavirus 42 drives digital papillary adenocarcinoma and elicits a germ-cell like program conserved in HPV-positive cancers. Cancer Discov 2022; https://doi.org/10.1158/2159-8290.CD-22-0489
  • Florence Oberkampf, Maya Gutierrez, Olfa Trabelsi Grati, Émilie Le Rhun, Olivier Trédan, Isabelle Turbiez, Amir Kadi, Coraline Dubot, Sophie Taillibert, Sophie Vacher, Claire Bonneau, Phase II study of intrathecal administration of trastuzumab in patients with HER2-positive breast cancer with leptomeningeal metastasis, Neuro-Oncology, 2022;, noac180, https://doi.org/10.1093/neuonc/noac180
  • Matthias Preusser, Antonio Silvani, Emilie Le Rhun, Riccardo Soffietti, Giuseppe Lombardi, Juan Manuel Sepulveda, Petter Brandal, Lucy Brazil, Alice Bonneville-Levard, Veronique Lorgis, Elodie Vauleon, Jacoline Bromberg, Sara Erridge, Alison Cameron, Florence Lefranc, Paul M Clement, Sarah Dumont, Marc Sanson, Charlotte Bronnimann, Carmen Balaná, Niklas Thon, Joanne Lewis, Maximilian J Mair, Philipp Sievers, Julia Furtner, Josef Pichler, Jordi Bruna, Francois Ducray, Jaap C Reijneveld, Christian Mawrin, Martin Bendszus, Christine Marosi, Vassilis Golfinopoulos, Corneel Coens, Thierry Gorlia, Michael Weller, Felix Sahm, Wolfgang Wick, Trabectedin for recurrent WHO grade 2 or 3 meningioma: A randomized phase II study of the EORTC Brain Tumor Group (EORTC-1320-BTG), Neuro-Oncology, Volume 24, Issue 5, May 2022, Pages 755–767, https://doi.org/10.1093/neuonc/noab243
  • Capuz A, Karnoub MA, Osien S, Rose M, Mériaux C, Fournier I, Devos D, Vanden Abeele F, Rodet F, Cizkova D, Salzet M The Antibody Dependant Neurite Outgrowth Modulation Response (ADNM) involvement in Spinal Cord Injury Front. Immunol. doi: 10.3389/fimmu.2022.882830
  • Guerra E, Relli V, Ceci M, Tripaldi R, Simeone P, Aloisi AL, Pantalone L, La Sorda R, Lattanzio R, Sacchetti A, Havas K, Guarnieri S, Vergara D, Fournier I, Salzet M, Tinari N, Piantelli M, Trerotola M, Alberti S Trop-2, Na +/K + ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion Oncogene. 2022 Feb 7. doi: 10.1038/s41388-022-02220-1
  • Hajjaji N, Aboulouard S, Cardon T, Bertin D, Robin YM, Fournier I, Salzet M Path to Clonal Theranostics in Luminal Breast Cancers Front Oncol. 2022 Jan 13;11:802177
  • Jeromel L, Ogrinc N,Siketic Z, Vavpetic P, Rupink Z, Bucar K, Jencic B, Kelemen M, Vencelj M, Vogel-Mikus K, Kovac J, Heeren RMA, Flinkers B, Pelicon P Molecular imaging of humain hair with MeV-SIMS: A case study of cocaine detection and distribution in the hair of a cocaine user Published: March 25, 2022 https://doi.org/10.1371/journal.pone.0263338
  • Ogrinc N, Attencourt C, Colin E, Boudahi A, Tebbakha R, Salzet M, Testelin S, Dakpé S, Fournier I Mass Spectrometry-Based Differentiation of Oral Tongue Squamous Cell Carcinoma and Nontumor Regions With the SpiderMass Technology  Original Resaerch Front Oral Health, 03 March 2022 https://doi.org/10.3389/froh.2022.827360
  • Ogrinc N, Schneider S, Bourmaud A, Gengler N, Salzet M, Fournier I Direct In Vivo Analysis of CBD- and THC-Acid Cannabinoids and Classification of Cannabis Cultivars Using SpiderMass Metabolites 2022, 12(6), 480; https://doi.org/10.3390/metabo12060480
  • Malaker M, Quanico, J, Raffo-Romero, A, Kobeissy, F, Aboulouard, S, Tierny, D, Salzet, M On-tissue spatially resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic landscape Cell chemical biology, 29(1), 30-42
  • Robin YM, Ogrinc N, Salzet M, Fournier I Diagnostic moléculaire des sarcomes en temps réel par la technologie SpiderMass Innovations & Thérapeutiques en Oncologie, 8(1), 42-48
  • Rose M, Duhamel, M, Aboulouard, S, Kobeissy, F, Tierny, D, Fournier, I, Salzet M Therapeutic anti-glioma effect of the combined action of PCSK inhibitor with the anti-tumoral factors secreted by Poly (I: C)-stimulated macrophages Cancer gene therapy, 29(1), 22-36
  • Le Rhun E, Devos, P, Winklhofer S, Lmalen H, Brandsma D, Kumthekar P, Weller M Prospective validation of a new imaging scorecard to assess leptomeningeal metastasis: a joint EORTC BTG and RANO effor Neuro Oncol. 2022 Feb 14:noac043
  • Minniti G, Le Rhun E Should radiotherapy be considered for the initial treatment of brain metastases ? Lancet Oncol. 2022 Feb;23(2):205-206
  • Preusser M, Silvani A, Le Rhun E, Soffietti R, Lombardi G, Sepulveda JM, Brandal P, Brazil L, Bonneville-Levard A, Lorgis V, Vauleon E, Bromberg J, Erridge S, Cameron A, Lefranc F, Clement PM, Dumont S, Sanson M, Bronnimann C, Balaná C, Thon N, Lewis J, Mair MJ, Sievers P, Furtner J, Pichler J, Bruna J, Ducray F, Reijneveld JC, Mawrin C, Bendszus M, Marosi C, Golfinopoulos V, Coens C, Gorlia T, Weller M, Sahm F, Wick W Trabectedin for recurrent WHO grade 2 or 3 meningioma: A randomized phase II study of the EORTC Brain Tumor Group (EORTC-1320-BTG) Neuro Oncol. 2022 May 4;24(5):755-767. doi: 10.1093/neuonc/noab243

Proceeding of Congress

  • Pirini F, Rossi T, Aboulouard S, Fosso B, Puccetti M, Ravaioli Sara,Tumedei MM, Cortesi M, Zanoni M, Magnani Luca, Martinelli G, Salzet M, Bravaccini S A multi-omics approach to study the host-microbiota interaction in breast cancer tissue Cancer Res 82 (4_Supplement): P5-06-04

Fundamentals

  • Kraus F, El Hajj H, Le Deley MC, Aissaoui O, Gachon B, Chevalier A, Abdeddaim C, Lemaire AS, Ben Haj Amor M, Sylla D, Leblanc E, Narducci F, Hudry D. A New Paradigm in Managing Advanced Ovarian Cancer: Differentiating Patients Requiring Neoadjuvant Treatment from Primary Cytoreduction. Cancers (Basel). 2021 Sep 30;13(19):4925. doi: 10.3390/cancers13194925. PMID: 34638409; PMCID: PMC8508489.https://doi.org/10.3390/cancers13194925
  • Aboulouard S, Wisztorski M, Duhamel M, Saudemont P, Cardon T, Narducci F, Lemaire AS, Kobeissy F, Leblanc E, Fournier I, Salzet M In-depth proteomics analysis of sentinel lymph nodes from individuals with endometrial cancer Cell Rep Med Jun 15;2(6):100318 Download PDF
  • Alfaro JA, Bohländer P, Dai M, Filius M, Howard CJ, van Kooten XF, Ohayon S, Pomorski A, Schmid S, Aksimentiev A, Anslyn EV, Bedran G, Cao C, Chinappi M, Coyaud E, Dekker C, Dittmar G, Drachman N, Eelkema R, Goodlett D, Hentz S, Kalathiya U, Kelleher NL, Kelly RT, Kelman Z, Kim SH, Kuster B, Rodriguez-Larrea D, Lindsay S, Maglia G, Marcotte EM, Marino JP, Masselon C, Mayer M, Samaras P, Sarthak K, Sepiashvili L, Stein D, Wanunu M, Wilhelm M, Yin P, Meller A, Joo C The emerging landscape of single-molecule protein sequencing technologies Nat Methods Jun;18(6):604-617. doi: 10.1038/s41592-021-01143-1
  • Bauzone M, Souidi M, Dessein AF, Wisztorski M, Vincent A, Gimeno JP, Monte D, Van Seuningen I, Gespach C, Huet G Cross-talk between YAP and RAR-RXR Drives Expression of Stemness Genes to Promote 5-FU Resistance and Self-Renewal in Colorectal Cancer Cells Mol Cancer Res. Apr;19(4):612-622 Download PDF
  • Brunet MA, Lucier JF, Levesque M, Leblanc S, Jacques JF, Al-Saedi HRH, Guilloy N, Grenier F, Avino M, Fournier I, Salzet M, Ouangraoua A, Scott MS, Boisvert FM, Roucou X OpenProt 2021: deeper functional annotation of the coding potential of eukaryotic genomes Nucleic Acids Res. 2021 Jan 8;49(D1):D380-D388. doi: 10.1093/nar/gkaa1036 Download PDF
  • Cardon T, Fournier I, Salzet M Unveiling a ghost proteome in the glioblastoma non-coding RNAs Frontiers in Cell and Developmental Biology Signaling (doi: 10.3389/fcell.2021.703583)
  • Chicano-Galvez E, Salzet M, Fournier I MALDI Mass Spectrometry Imaging and Spatially-resolved Proteomics MALDI Mass Spectrometry Imaging, 234-261
  • Colin F, Schauer K, Hamiche A, Martineau P, Borg JP, Bednar J, Bertolin G, Camoin L, Collette Y, Dimitrov S, Fournier I, Hyenne V, Mendoza-Parra MA, Morelli X, Rondé P, Sumara I, Tramier M, Schultz P, Goetz JG The NANOTUMOR consortium - towards the Tumor Cell Atlas doi.org/10.1111/boc.202000135 Download PDF
  • Damato M, Cardon T, Wisztorski M, Fournier I, Pieragostino D, Cicalini I, Salzet M, Vergara D, Maffia M Protein Kinase C Activation Drives a Differentiation Program in an Oligodendroglial Precursor Model through the Modulation of Specific Biological Networks Int. J. Mol. Sci. 22(10), 5245 Download PDF
  • Drelich L, Aboulouard S, Franck J, Salzet M, Fournier I, Wisztorski M Toward High Spatially Resolved Proteomics Using Expansion Microscopy Anal Chem Sep 14;93(36):12195-12203
  • Faure MC, Khoueiry R, Quanico J, Acloque H, Guerquin MJ, Bertoldo MJ, Chevaleyre C, Ramé C, Fournier I, Salzet M, Dupont J, Froment P In Utero Exposure to Metformin Reduces the Fertility of Male Offspring in Adulthood. Front Endocrinol (Lausanne). 2021 Oct 18;12:750145
  • Go CD, Knight JDR, Rajasekharan A, Rathod B, Hesketh GG, Abe KT, Youn JY, Samavarchi-Tehrani P, Zhang H, Zhu LY, Popiel E, Lambert JP, Coyaud É, Cheung SWT, Rajendran D, Wong CJ, Antonicka H, Pelletier L, Palazzo AF, Shoubridge EA, Raught B, Gingras AC A proximity-dependent biotinylation map of a human cell Nature Jun 2 doi: 10.1038/s41586-021-03592-2 Download PDF 1 and PDF 2
  • Hajjaji N, Aboulouard S, Cardon T, Bertin D, Robin YM, Fournier I, Salzet M Path to clonal theranostics in luminal breast cancers Frontiers in Oncology (DOI; 10.3389/fonc.2021.802177)
  • Hirtz C, Mannaa AM, Moulis E, Pible O, O'Flynn R, Armengaud J, Jouffret V, Lemaistre C, Dominici G, Yahiaoui Martinez A, Dunyach Remy C, Tiers L, Lavigne JP, Tramini P, Goldsmith MC, Lehmann S, Deville de Périère D, Vialeret J Deciphering Black Extrinsic Tooth Stain Composition in Children using metaproteomics Doi.org/10.1021/acsomega.1c04770 ACS Omega Download PDF
  • Kalathiya U, Padariya M, Faktor J, Coyaud E, Alfaro JA, Fahraeus R, Hupp TR, Goodlett DR Interfaces with Structure Dynamics of the Workhorses fromCells Revealed through Cross-Linking MassSpectrometry (CLMS) Biomolecules 2021 Mar 4;11(3):382 Download PDF
  • Malaker SA, Quanico J, Raffo Romero A, Bertozzi CR, Fournier I, Salzet M On-tissue spatially resolved glycoproteomics guided by N-glycan imaging reveal global dysregulation of canine glioma glycoproteomic lanscape Cell Chem. Biol Doi.org/10.1016/j.chembiol.2021.05.007
  • Mallah K, Zibara K, Kerbaj C, Eid A, Khoshman N, Ousseily Z, Kobeissy A, Cardon T, Cizkova D, Kobeissy F, Fournier I, Salzet M. Neurotrauma investigation through spatial omics guided by mass spectrometry imaging: Target identification and clinical applications Mass Spectrom Rev Jul 29. doi: 10.1002/mas.21719
  • Nekoua MP, Bertin A, Sane F, Gimeno JP, Fournier I, Salzet M, Engelmann I, Alidjinou EK, Hober D Persistence of Coxsackievirus B4 in PancreaticβCells DisturbsInsulin Maturation, Pattern of Cellular Proteins, and DNA Methylation Microorganisms 9(6), 112 Download PDF
  • Ogrinc N, Saudemont P, Takats Z, Salzet M, Fournier I Cancer Surgery 2.0: Guidance by Real-Time Molecular Technologies Trends Mol Med Jun;27(6):602-615. doi: 10.1016/j.molmed.2021.04.001 Download PDF
  • Ogrinc N, Caux PD, Robin YM, Bouchaert E, Fatou B, Ziskind M, Focsa C, Bertin D, Tierny D, Takats Z, Salzet M, Fournier I Direct Water-Assisted Laser Desorption/Ionization Mass Spectrometry Lipidomic Analysis and Classification of Formalin-Fixed Paraffin-Embedded Sarcoma Tissues without Dewaxing Clin Chem Sep 29:hvab160 doi: 10.1093/clinchem/hvab160
  • Ogrinc N, Caux PD, Robin YM, Bouchaert E, Fatou B, Ziskind M, Focsa C, Bertin D, Takats Z, Salzet M, Fournier I Direct Water-Assisted Laser Desorption/Ionization Mass Spectrometry Lipidomic Analysis and Classification of Formalin-Fixed Paraffin-Embedded Sarcoma Tissues without Dewaxing Clinical chemistry 67 (11), 1513-1523
  • Ogrinc N, Kruszewski A, Chaillou P, Saudemont P, Lagadec C, Salzet M, Duriez C, Fournier I Robot-Assisted SpiderMass for In Vivo Real-Time Topography Mass Spectrometry Imaging Analytical chemistry 93 (43), 14383-14391
  • Rose M, Duhamel M, Rodet F, Salzet M The Role of Proprotein Convertases in the Regulation of the Function of Immune Cells in the Oncoimmune Response Front Immunol Apr 29;12:667850 doi: 10.3389/fimmu.2021.667850 Download PDF
  • Rose M, Cardon T, Aboulouard S, Hajjaji N, Kobeissy F, Duhamel M, Fournier I, Salzet M Surfaceome Proteomic of Glioblastoma Revealed Potential Targets for Immunotherapy Front Immunol Sep 27;12:746168 Download PDF
  • Touboul D, Fournier I Chemobiologie : Apport des outils de chémobiologie à l’imagerie par spectrométrie de masse L'actualité chimique Download PDF

Proceeding of Congress

In Press

  • Ogrinc N, Kruszewski A, Chaillou P, Saudemont P, Lagadec C, Salzet M, Duriez C, Fournier I Robot-Assisted SpiderMass for in vivo Real-Time Topography Mass Spectrometry Imaging Anal. Chem

Under revision

  • Hirtz C, Mannaa A, Moulis E, Pible O, R O’Flynn, Armengaud J, Jouffret V, Lemaistre C, Dominici G, Yahiaoui Martinez A, Remy C, Tiers L, Lavigne JP, Tramini P, Goldsmith MC, Lehmann S, Deville de Périère D, Vialaret J A meta-proteomics approach for the analysis of Black Extrinsic Tooth Stains in Children ACS Omega
  • Mannaa A, Way L, Hernychova L, Ruidong L, Hupp T, Vojtesek B The Nutlin-3 Responsive Proteome Increases As a Function Of Cell Density. Frontiers in Oncology, section Molecular and Cellular Oncology
  • Rocha H, Ferreira R, Manadas B, Francisco A, Guedes S, Mannaa A, Valiaret J, Hirtz C, Vitorino R Dried matrix spots applied to proteomics and metabolomics Proteomics Clinical Applications
  • Zaqout S, Mannaa A, Klein O, Klose J, Elsabagh A, Ferih K,Kramer N, Ravindran E, Kaindl AM Proteome changes in autosomal recessive primary microcephaly Proteomics (Wiley&Sons)

Clinicals

Fundamentals

  • Blateau P, Coyaud E, Laurent E, Béganton B, Ducros V, Chauchard G, Vendrell J.A, Solassol J TERT Promoter Mutation as an Independent Prognostic Marker for Poor Prognosis MAPK Inhibitors-Treated Melanoma Cancers Basel Aug 9;12(8):2224 Download PDF
  • Bujňáková D, Čuvalová A, Čížek M, Humenik F, Salzet M, Čížková D Canine Bone Marrow Mesenchymal Stem Cell Conditioned Media Affect Bacterial Growth, Biofilm-Associated Staphylococcus aureus and AHL-Dependent Quorum Sensing Microorganisms Sep 26;8(10):E1478. doi: 10.3390/microorganisms8101478 PMID: 32993120 Download PDF
  • Cardon T, Fournier I, Salzet M SARS-Cov-2 Interactome with Human Ghost Proteome: A Neglected World Encompassing a Wealth of Biological Data Microorganisms. 2020 Dec 19;8(12):2036. doi: 10.3390/microorganisms8122036 Download PDF
  • Cardon T, Fournier I, Salzet M Shedding Light on the Ghost Proteome Trends Biochem Sci. 2020 Nov 24:S0968-0004(20)30265-6. doi: 10.1016/j.tibs.2020.10.003
  • Cardon T, Ozcan B, Aboulouard S, Kobeissy F, Duhamel M, Rodet F, Fournier I, Salzet M Epigenetic Studies Revealed a Ghost Proteome in PC1/3 KD Macrophages under Antitumoral Resistance Induced by IL-10 ACS Omega Download PDF
  • Cardon T, Herve F, Delcourt V, Roucou X, Salzet M, Franck J, Fournier I Optimized Sample Preparation Workflow for Improved Identification of Ghost Proteins Anal Chem Jan 7;92(1):1122-1129 Download PDF
  • Cardon T, Franck J, Damato M, Maffia M, Vergara D, Fournier I, Salzet M Alternative Proteins are Functional Regulators in Cell Reprogramming by PKA Activation Nucleic Acid Research Apr 23:gkaa277 Download PDF
  • Connaughton DM, Dai R, Owen DJ, Marquez J, Mann N, Graham-Paquin AL, Nakayama M, Coyaud E, Laurent E, St-Germain JR, Snijders Blok L, Vino A, Kla¨mbt V, Deutsch K, Wu CHW, Kolvenbach CM, Kause F, Ottlewski I, Schneider R, Kitzler TM, Majmundar AJ, Buerger F, Onuchic-Whitford AC, Youying M, Kolb A, Salmanullah D, Chen E, van der Ven AT, Rao J, Ityel H, Seltzsam S, Rieke JM, Chen J, Vivante A, Hwang DY, Kohl S, Dworschak GC Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations Am J Hum Genet Oct 1;107(4):727-742 Download PDF
  • Dae-Kyum K, J. Knapp J, Kuang D, Chawla A, Cassonnet P, Lee H, Sheykhkarimli D, Samavarchi-Tehrani P, Abdouni H, Rayhan A, Li R, Pogoutse O, Coyaud E, van der Werf S, Demeret C, Gingras AC, Taipale M, Raught B, Jacob Y, Roth FP A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions G3 (Bethesda) Sep 2;10(9):3399-3402 Download PDF
  • Gonnet J, Poncelet L, Meriaux C, Gonçalves E, Weiss L, Tchitchek N, Pedruzzi E, Soria A, Boccara D, Vogt A, Bonduelle O, Hamm G, Ait-Belkacem R, Stauber J, Fournier I, Wisztorski M, Combadiere B Mechanisms of innate events during skin reaction following intradermal injection of seasonal influenza vaccine J Proteomics Jan 25:103670 Download PDF
  • Gross-Amat O, Guillen M, Gimeno JP, Salzet M, Lebonvallet N, Misery L, Auxenfans C, Nataf S Molecular Mapping of Hydrogen Sulfide Targets in Normal Human Keratinocytes Int J Mol Sci. 2020 Jun 30;21(13):4648. doi: 10.3390/ijms211346 Download PDF
  • Lemaire Q, Duhamel M, Raffo Romero A, Salzet M, Lefebvre C Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment Journal of visualized experiments JoVE Jun 2;(160) Download PDF
  • Murgoci AN*, Duhamel M*, Raffo-Romero A, Mallah K, Aboulouard S, Lefebvre C, Kobeissy F, Fournier I, Zilkova M, Maderova D, Cizek M, Cizkova D, Salzet M Location of neonatal microglia drives smallextracellular vesicles content and biologicalfunctions in vitro Journal of Extracellular Vesicles Feb 18;9(1):1727637 Download PDF
  • Murgoci AN*, Cardon T , Soulaimane S, Duhamel M*, Fournier I, Cizkova D, Salzet M Reference and Ghost proteins identification in Rat C6 glioma extracellular vesicles using Tryspin/lys C digestion followed by amicon filtration and Shot gun proteomic ISciences May 22;23(5):101045 Download PDF
  • Rose M*, Duhamel M*, Aboulouard S, Kobeissy F, Le Rhun E, Desmons A, Tierny D, Fournier I, Rodet F, Salzet M The role of a proprotein convertases inhibitor in reactivation of tumor associated macrophages and inhibition of glioma growth Molecular Therapeutic Oncolytics0 Mar 31;17:31-46 IScience Download PDF
  • Seddiki K, Saudemont P, Precioso F, Ogrinc N, Wisztorski M, Salzet M, Fournier I, Droit A Cumulative learning enables convolutional neural network representations for small mass spectrometry data classification Nat Commun. 2020 Nov 5;11(1):5595
  • Vergara D, Ravaioli S, Fonzi E, Adamo L, Damato M, Bravaccini S, Pirini F, Gaballo A, Barbano R, Pasculli B, Franck J, Fournier I, Salzet M, Maffia M Carbonic Anhydrase XII Expression Is Modulated during Epithelial Mesenchymal Transition and Regulated through Protein Kinase C Signaling Int J Mol Sci Jan 22;21(3):715 Download PDF
  • Vergara D, Verri T, Damato M, Trerotola M, Simeone P, Franck J, Fournier I, Salzet M, Maffia M A hidden human proteome signature characterizes the epithelial mesenchymal transition program Curr Pharm Des 26(3):372-375

Proceeding of Congress

  • Hajjaji N, Aboulouard S, Robin YM, Bertin D, Bonneterre J, Fournier I, Salzet M Functional proteomic characterization of early luminal breast cancers with discordant genomic and clinical risk estimates Cancer Research 80 (4 Supplement), P4-07-08-P4-07-08
  • Hajjaji N, Abbouchi M, Nguyen LA, Charles S, Leclercq S, Bertin D, Robin YM, Fournier I, Salzet M A novel proteomic mass spectrometry-based approach to reveal functionally heterogeneous tumor clones in breast cancer metastases and identify clone-specific drug targets Journal of Clinical Oncology 38 (15_suppl), e13063-e13063
  • Leblanc E, Narducci F, Hudry D, Mailliez A, Lemaire AS, Tresch-Bruneel E, Salzet M, Pomel C, Caquant F, Houvenaeghel G, Charvolin JY, Crouzet A, Guyon F, Fouche Y, Ferron G, Gouy S, Vaini-Cowen V, Fourchotte V, Golfier F, Collinet P Results of a prospective phase II national study : Prophylactic radical fimbriectomy (NCT01608074), in women with a documented high risk of breast/ovarian cancer Final pathological results and outcomes Journal of Clinical Oncology 38 (15_suppl), 1594-1594

Clinicals

  • Bonne NX, Hanson JN, Gauvrit F, Risoud M, Vincent C Long-term evaluation of sound localisation in single-sided deaf adults fitted with a BAHA device Clin Otolaryngol Nov;44(6):898-904 Download PDF
  • Bonne NX, Risoud M, Hoa M, Lemesre PE, Aboukais R, Le Rhun E, Dubrulle F, Baroncini M, Lejeune JP, Vincent C Hearing Response Following Internal Auditory Canal Decompression in Neurofibromatosis Type 2 Neurosurgery Sep 1;85(3):E560-E567
  • Clemens E, Van Den Heuvel-Eibrink MM, Mulder RL, Kremer LCM, Hudson MM, Skinner R, Constine LS, Bass JK, Kuehni CE, Langer T, Van Dalen EC, Bardi E, Bonne NX, Brock PR, Brooks B, Carleton B, Caron E, Chang KW, Johnston K, Knight K, Nathan PC, Orgel E, Prasad PK, Rottenberg J, Scheinemann K, de Vries ACH, Walwyn T, Weiss A, Am Zehnhoff-Dinnesen A, Cohn RJ, Landier W International Guideline Harmonization Group ototoxicity group. Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium Lancet Oncol Jan;20(1):e29-e41 Download PDF
  • Dufour C, Perbet R, Leblond P, Vasseur R, Stechly L, Pierache A, Reyns N, Touzet G, Le Rhun E, Vinchon M, Maurage CA, Escande F, Renaud F Identification of prognostic markers in diffuse midline gliomas H3K27M-mutant Brain Pathol Jan;30(1):179-190 Download PDF
  • Galldiks N, Kocher M, Ceccon G, Werner JM, Brunn A, Deckert M, Pope WB, Soffietti R, Le Rhun E, Weller M, Tonn JC, Fink GR, Langen KJ Imaging challenges of immunotherapy and targeted therapy in patients with brain metastases: response, progression, and pseudoprogression Neuro Oncol Jan 11;22(1):17-30 Download PDF
  • Hajjaji N, Robin YM, Bonneterre J Should a Multigene Signature be Used in all Luminal Early Breast Cancers Front Oncol Jun 4;9:454 Download PDF
  • Le Rhun E, Seoane J, Salzet M, Soffietti R, Weller M Liquid biopsies for diagnosing and monitoring primary tumors of the central nervous system Cancer Lett Jun 28;480:24-28 Download PDF
  • Le Rhun E, Wallet J, Mailliez A, Le Deley MC, Rodrigues I, Boulanger T, Lorgis V, Barrière J, Robin YM, Weller M, Bonneterre J Intrathecal liposomal cytarabine plus systemic therapy versus systemic chemotherapy alone for newly diagnosed leptomeningeal metastasis from breast cancer Neuro Oncol Apr 15;22(4):524-538 Download PDF
  • Le Rhun E, Weller M, Niclou SP, Short S, Piil K, Boele F, Rudà R, Theodorou M, Brandsma D, van den Bent M, Dirven L Gender issues from the perspective of health-care professionals in Neuro-oncology: an EANO and EORTC Brain Tumor Group survey Neurooncol Pract Mar;7(2):249-259
  • Le Rhun E, Weller M, Le Deley MC DEPOSEIN-how meaningful was the benefit from intrathecal chemotherapy ? Neuro Oncol. 2020 Nov 26;22(11):1710-1711
  • Le Rhun E, Devos P, Weller J, Seystahl K, Mo F, Compter A, Berghoff AS, Jongen JLM, Wolpert F, Rudà R, Brandsma D, van den Bent M, Preusser M, Herrlinger U, Weller M Prognostic validation and clinical implications of the EANO ESMO classification of leptomeningeal metastasis from solid tumors Neuro Oncol. Dec 23:noaa298
  • Lombardi G, Idbaih A, Le Rhun E, Preusser M, Zagonel V, French P A New Landscape for Systemic Pharmacotherapy of Recurrent Glioblastoma ? Cancers (Basel) Dec 15;12(12):3775 Download PDF
  • Marx M, Mosnier I, Vincent C, Bonne NX, Bakhos D, Lescanne E, Flament J, Bernardeschi D, Sterkers O, Fraysse B, Lepage B, Godey B, Schmerber S, Uziel A, Mondain M, Venail F, Deguine O Treatment choice in single-sided deafness and asymmetric hearing loss. A prospective, multicentre cohort study on 155 patients Clin Otolaryngol Nov 24. doi: 10.1111/coa.13672
  • Pace A, Koekkoek JAF, van den Bent MJ, Bulbeck HJ, Fleming J, Grant R, Golla H, Henriksson R, Kerrigan S, Marosi C, Oberg I, Oberndorfer S, Oliver K, Pasman HRW, Le Rhun E, Rooney AG, Rudà R, Veronese S, Walbert T, Weller M, Wick W, Taphoorn MJB, Dirven L Determining medical decision-making capacity in brain tumor patients: why and how ? Neurooncol Pract Jul 16;7(6):599-612
  • Penel N, Lebellec L, Blay JY, Robin YM Overview of « druggable » alterations by histological subtypes of sarcomas and connective tissue intermediate malignancies Crit Rev Oncol Hematol Jun;150:102960. doi: 10.1016/j.critrevonc.2020.102960 Download PDF
  • Risoud M, Tardivel M, Lemesre PE, Bonne NX, Vincent C Optimised immunofluorescence method on cleared intact Mongolian gerbil cochlea Eur Ann Otorhinolaryngol Head Neck Dis Feb 18 Download PDF
  • Risoud M, Hanson JN, Gauvrit F, Renard C, Bonne NX, Vincent C Azimuthal sound source localization of various sound stimuli under different conditions Eur Ann Otorhinolaryngol Head Neck Dis Jan;137(1):21-29 Download PDF
  • Risoud M, Bonne NX, Vincent C Anaplastic lymphoma and silicone in cochlear implants: Let's reassure Eur Ann Otorhinolaryngol Head Neck Dis Oct;136(5):339 Download PDF
  • Roth P, Pace A, Le Rhun E, Weller M, Ay C, Cohen-Jonathan Moyal E, Coomans M, Giusti R, Jordan K, Nishikawa R, Winkler F, Hong JT, Ruda R, Villà S, Taphoorn MJB, Wick W Executive Board Neurological and vascular complications of primary and secondary brain tumours: EANO-ESMO Clinical Practice Guidelines for prophylaxis, diagnosis, treatment and follow-up Ann Oncol.Feb;32(2):171-182
  • Von Achenbach C, Le Rhun E, Sahm F, Wang SS, Sievers P, Neidert MC, Rushing EJ, Lawhon T, Schneider H, von Deimling A, Weller M Sensitivity of human meningioma cells to the cyclin-dependent kinase inhibitor, TG02 Transl Oncol Dec;13(12):100852
  • Weller M, Le Rhun E How did lomustine become standard of care in recurrent glioblastoma ? Cancer Treat Rev May 4;87:102029 Download PDF
  • Wen PY, Weller M, Lee EQ, Alexander BA, Barnholtz-Sloan JS, Barthel FP, Batchelor TT, Bindra RS, Chang SM, Chiocca EA, Cloughesy TF, DeGroot JF, Galanis E, Gilbert MR, Hegi ME, Horbinski C, Huang RY, Lassman AB, Le Rhun E, Lim M, Mehta MP, Mellinghoff IK, Minniti G, Nathanson D, Platten M, Preusser M, Roth P, Sanson M, Schiff D, Short SC, Taphoorn MJB, Tonn JC, Tsang J, Verhaak RGW, von Deimling A, Wick W, Zadeh G, Reardon DA, Aldape KD, van den Bent MJ Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions Neuro Oncol Apr 24:noaa106
  • Wolpert F, Lareida A, Terziev R, Grossenbacher B, Neidert MC, Roth P, Poryazova R, Imbach LL, Le Rhun E, Weller M Risk factors for the development of epilepsy in patients with brain metastases Neuro Oncol May 15;22(5):718-728

Fundamentals

  • Arab T, Raffo-Romero A, Van Camp C, Le Marrec F, Aboulouard S, Slomianny C, Lacoste AS, Guigon I, Salzet M, Fournier I, Lefebvre C, Vizioli J, Sautière PE Proteomic characterization of leech microglia extracellular vesicles (EVs): comparison between differential ultracentrifugation and Optiprep™ density gradient isolation Journal of Extracellular Vesicles (2019) 8 (1), 1603048 Download PDF
  • Brunet MA, Brunelle M, Lucier JF, Delcourt V, Levesque M, Grenier F, Samandi S, Leblanc S, Aguilar JD, Dufour P, Jacques JF, Fournier I, Ouangraoua A, Scott MS, Boisvert FM, Roucou X OpenProt : a more comprehensive guide to explore eukaryotic coding potential and proteomes Nucleic Acids Res. 2019 Jan 8;47(D1):D403-D410 Download PDF
  • Cameron SJS, Bodai Z, Temelkuran B, Perdones-Montero A, Bolt F, Burke A, Alexander-Hardiman K, Salzet M, Fournier I, Rebec M, Takáts Z Utilisation of Ambient Laser Desorption Ionisation Mass spectrometry (ALDI-Ms) Improves Lipid-Based Microbial species Level Identification Sci Rep. 2019 Feb 28;9(1):3006 Download PDF
  • Cardon T, Salzet M, Franck J, Fournier I Nuclei of HeLa cells interactomes unravel a network of ghost proteins involved in proteins translation Biochim Biophys Acta Gen Subj. 2019 May 23. pii: S0304-4165(19)30130-8 Download PDF
  • Cizkova D, Murgoci AN, Cubinkova V, Humenik F, Mojzisova Z, Maloveska M, Cizek M, Fournier I, Salzet M Spinal Cord Injury : Animal Models, Imaging Tools and the Treatment Strategies Neurochemical Research doi.org/10.1007/s11064-019-02800-w Download PDF
  • Cizkova D, Cubinkova V, Zilkova M, Devaux S, Murgoci AN, Mojzisova Z, Salzet M Immune profile following acute spinal cord injury Eur. J. Immunol. 2019. 49 (Suppl. 4): 1–75
  • Fatou B, Salzet M, Fournier I Real time human micro-organisms biotyping based on Water-Assisted Laser Desorption/Ionization The EuroBiotech Journal 3 (2), 97-104 Download PDF and the supplementary
  • Fournier I, Salzet M Mass spectrometry-based intraoperative tumor diagnostics: a letter in reply Future Sci OA. 2019 Aug 1;5(7):FSO403 Donwload PDF
  • Geirsdottir L, David E, Keren-Shaul H, Weiner A, Bohlen SC, Neuber J, Balic A, Giladi A, Sheban F, Dutertre CA, Pfeifle C, Peri F, Raffo-Romero A, Vizioli J, Matiasek K, Scheiwe C, Meckel S, Mätz-Rensing K, van der Meer F, Thormodsson FR, Stadelmann C, Zilkha N, Kimchi T, Ginhoux F, Ulitsky I, Erny D, Amit I, Prinz M Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program Cell. 2019 Dec 12;179(7):1609-1622.e16. doi: 10.1016/j.cell.2019.11.010 Download PDF
  • Giudetti A, De Domenico S, Ragusa A, Lunetti P, Gaballo A, Franck J, Simeone P, Nicolardi G, De Nuccio F, Santino A, Capobianco L, Lanuti P, Fournier I, Salzet M, Maffia M, Vergara D A specific lipid metabolic profile is associated with the epithelial mesenchymal transition program. BBA - Molecular and Cell Biology of Lipids (2019) 1864 (3), 344-357 Download PDF
  • Humenik F, Cizkova D, Cikos S, Luptakova L, Madari A, Mudronova D, Kuricova M, Farbakova J, Spirkova A, Petrovova E, Cente M, Mojzisova Z, Aboulouard S, Murgoci AN, Fournier I, Salzet M Canine bone marrow derived mesenchymal stem cells : Genomics, Proteomics and Functional Analyses of Paracrine Factor Mol Cell Proteomics. 2019 Jul 8. pii: mcp.RA119.001507 Download PDF
  • Jencic B, Sepec L, Vavpetic P, Kelemen M, Rupnik Z, Vencelj M, Vogel-Mikus K, Ogrinc N, R.Ellis S, M.A.Heeren R, Pelicon P Stigmatic imaging of secondary ions in MeV-SIMS spectrometry by linear Time-of-Flight mass spectrometer and the TimePix detector ScienceDirect Download PDF
  • Lazzaro S, Ogrinc N, Lamont L, Vecchio G, Pappalardo G, M. A. Heeren R Ion mobility spectrometry combined with multivariate statisticalanalysis: revealing the effects of a drug candidate for Alzheimer’sdisease on Aβ1-40 peptide early assembly Analytical and Bioanalytical Chemistry (2019) 411:6353–6363 doi.org/10.1007/s00216-019-02030-7 Download PDF
  • Lemaire Q, Duhamel M, Raffo Romero A, Salzet M, Lefebvre C Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment J Vis Exp (Pending Publication) e60118 In-press
  • Lemaire Q, Raffo Romero A, Arab T, Van Camp C, Drago F, Forte S, Gimeno JP, Begard S, Colin M, Vizioli J, Sautière PE, Salzet M, Lefebvre C Isolation of microglia-derived extracellular vesicles : towards miRNA signatures and neuroprotection J Nanobiotechnology. 2019 Dec 4;17(1):119 Download PDF
  • Mallah K, Quanico J, Raffo-Romero A, Cardon T, Aboulouard S, Devos D, Kobeissy F, Zibara K, Salzet M, Fournier I Mapping spatiotemporal microproteomics landscape in experimental model of traumatic brain injury unveils a link to Parkinson's disease Mol Cell Proteomics 2019 Jun 16 pii: mcp.RA119.001604 Download PDF
  • Mallah K, Quanico J, Raffo-Romero A, Cardon T, Aboulouard S, Devos D, Kobeissy F, Zibara K, Salzet M, Fournier I MALDI MSI of Lipids in Experimental Model of Traumatic Brain Injury Detects Acylcarnitines as Injury Related Markers Anal Chem. 2019 Aug 14. doi: 10.1021/acs.analchem.9b02633 Download PDF
  • Maulouet T, Fatou B, Focsa C, Salzet M, Fournier I, Ziskind M Optimizing the substrate-mediated laser ablation of biological tissues : Quest for the best substrate material Surface Science (2019) 473, 486-492 Download PDF
  • Mulder IA, Ogrinc Potočnik N, Broos LAM, Prop A, Wermer MJH, Heeren RMA, Van Den Maagdenberg A Distinguishing core from penumbra by lipid profiles using Mass spectrometry Imaging in a transgenic mouse model of ischemic stroke Scientific Reports 9(1):1090 Download PDF
  • Ogrinc N, Saudemont P, Balog J, Robin YM, Gimeno JP, Pascal Q, Tierny D, Takats Z, Salzet M, Fournier I Water-assisted laser desorption/ionizationmass spectrometry for minimally invasive in vivoand real-time surface analysis using SpiderMass Nature Protocols doi.org/10.1038/s41596-019-0217-8 Download PDF
  • Raffo Romero A, Arab T, Van camp C, Lemaire Q, Wisztorski M, Franck J, Le Marrec-Croq F, Sautiere PE, Vizioli J, Salzet M, Lefebvre C ALK4/5-dependent TGF-b signaling contributes to the crosstalk between neurons and microglia following axonal lesion Sci. report 9(1):6896 Download PDF
  • Rodet F, Capuz A, Ozcan BA, Le Beillan R, Raffo-Romero A, Kobeissy F, Duhamel M, Salzet M PC1/3 KD Macrophages Exhibit Resistance to the Inhibitory Effect of IL-10 and a Higher TLR4 Activation Rate, Leading to an Anti-Tumoral Phenotype Cells 2019 Nov 22;8(12). pii: E1490. doi: 10.3390/cells8121490 Download PDF
  • Vergara D, Nigro A, Romano A, De Domenico S, Damato M, Franck J, Coricciati C, Wistorski M, Cardon T, Fournier I, Quattrini A, Salzet M, Furlan R, Maffia M Distinct Protein Expression Networks are Activated in Microglia Cells after Stimulation with IFN-γ and IL-4 Cells 2019 Jun 12;8(6). pii: E580 Download PDF

    (Processing of Congress)

  • Hajjaji N, Aboulouard S, Robin YM, Bertin D, Fournier I, Bonneterre J, Salzet M Proteomic profile of PAM50 intermediate risk early breast cancers Cancer Research 79,  4 P3-08-15-P3-08-15

  • Hajjaji N, Aboulouard S, Robin YM, Bertin D, Fournier I, Bonneterre J, Salzet M Proteomic tracking of breast cancer metastasis progression Cancer Research 79,  4 P3-08-19-P3-08-19

  • Hajjaji N, Aboulouard S, Robin YM, Bertin D, Fournier I, Bonneterre J, Salzet M Proteomic profile of high-risk luminal A early breast cancers Journal of Clinical Oncology 37 (15_suppl), 3077-3077

Clinicals

  • Belhadia M, Narducci F, Leblanc E, Borghesi Y, Boukerrou M, Hersant B How I do… to use indocyanine green to check the flap viability in vaginal reconstruction Gynecol Obstet Fertil Senol. 2019 Feb 25. pii: S2468-7189(19)30075-3 Download PDF
  • Bonne NX, Risoud M, Hoa M, Lemesre PE, Aboukais R, Le Rhun E, Dubrulle F, Baroncini M, Lejeune JP, Vincent C Hearing Response Following Internal Auditory Canal Decompression in Neurofibromatosis Type 2 Neurosurgery. 2019 Sep 1;85(3):E560-E567
  • Boire A, Brandsma D, Brastianos PK, Le Rhun E, Ahluwalia M, Junk L, Glantz M, Groves MD, Lee EQ, Lin N, Raizer J, Rudà R, Weller M, van den Bent MJ, Vogelbaum MA, Chang S, Wen PY, Soffietti R Liquid biopsy in Central Nervous System metastases: a RANO review and proposals for clinical applications Neuro Oncol. 2019 Jan 22. doi: 10.1093/neuonc/noz012 Download PDF
  • Clemens E, van den Heuvel-Eibrink MM, Mulder RL, Kremer LCM, Hudson MM, Skinner R, Constine LS, Bass JK, Kuehni CE, Langer T, van Dalen EC, Bardi E, Bonne NX, Brock PR, Brooks B, Carleton B, Caron E, Chang KW, Johnston K, Knight K, Nathan PC, Orgel E, Prasad PK, Rottenberg J, Scheinemann K, de Vries ACH, Walwyn T, Weiss A, Am Zehnhoff-Dinnesen A, Cohn RJ, Landier W Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium International Guideline Harmonization Group ototoxicity group. Lancet Oncol. 2019 Jan;20(1):e29-e41. doi: 10.1016/S1470-2045(18)30858-1 Download PDF
  • Galldiks N, Langen KJ, Albert NL, Chamberlain M, Soffietti R, Kim MM, Law I, Le Rhun E, Chang S, Schwarting J, Combs SE, Preusser M, Forsyth P, Pope W, Weller M, Tonn JC PET Imaging in Patients with Brain Metastasis - Report of the RANO/PET Group Neuro Oncol. 2019 Jan 5. doi: 10.1093/neuonc/noz003 Download PDF
  • Hajjaji N, Robin YM, Bonneterre J Should a Multigene Signature be Used in all Luminal Early Breast Cancers Front Oncol. 4;9:454. doi:10.3389/fonc.2019.00454. eCollection 2019. PubMed PMID: 31214499
  • Hudry D, Narducci F, Andrade C, Leblanc E Extra-peritoneal para-aortic lymphadenectomy by robot assisted laparoscopy (EPLRL) in 10 steps Gynecol Oncol Oct;155(1):170-171
  • Penel N, Robin YM, Blay JY Personalised management of alveolar soft part sarcoma: a promising phase 2 study Lancet Oncol Jun;20(6):750-752
  • Pivot X, Romieu G, Debled M, Pierga JY, Kerbrat P, Bachelot T, Lortholary A, Espié M, Fumoleau P, Serin D, Jacquin JP, Jouannaud C, Rios M, Abadie-Lacourtoisie S, Venat-Bouvet L, Cany L, Catala S, Khayat D, Gambotti L, Pauporté I, Faure-Mercier C, Paget-Bailly S, Henriques J, Grouin JM PHARE trial investigators 6 months versus 12 months of adjuvant trastuzumab in early breast  cancer (PHARE): final analysis of a multicentre, open-label, phase 3 randomised trial Lancet Jun 29;393(10191):2591-2598. doi:10.1016/S0140-6736(19)30653-1. PubMed PMID: 3117815
  • Lavoué V, Huchon C, Akladios C, Alfonsi P, Bakrin N, Ballester M, Bendifallah S, Bolze PA, Bonnet F, Bourgin C, Chabbert-Buffet N, Collinet P, Courbiere B, De la Motte Rouge T, Devouassoux-Shisheboran M, Falandry C, Ferron G, Fournier L, Gladieff L, Golfier F, Gouy S, Guyon F, Lambaudie E, Leary A, Lécuru F, Lefrère-Belda MA, Leblanc E, Lemoine A, Narducci F, Ouldamer L, Pautier P, Planchamp F, Pouget N, Ray-Coquard I, Rousset-Jablonski C, Sénéchal-Davin C, Touboul C, Thomassin-Naggara I, Uzan C, You B, Daraï E Part I drafted from the short text of the French Guidelines entitled "Initial management of patients with epithelial ovarian cancer" developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY and endorsed by INCa (Diagnosis management, surgery, perioperative care, and pathological analysis) Gynecol Obstet Fertil Senol. 2019 Feb;47(2):100-110 Download PDF
  • Lavoué V, Huchon C, Akladios C, Alfonsi P, Bakrin N, Ballester M, Bendifallah S, Bolze PA, Bonnet F, Bourgin C, Chabbert-Buffet N, Collinet P, Courbiere B, De la Motte Rouge T, Devouassoux-Shisheboran M, Falandry C, Ferron G, Fournier L, Gladieff L, Golfier F, Gouy S, Guyon F, Lambaudie E, Leary A, Lécuru F, Lefrère-Belda MA, Leblanc E, Lemoine A, Narducci F, Ouldamer L, Pautier P, Planchamp F, Pouget N, Ray-Coquard I, Rousset-Jablonski C, Sénéchal-Davin C, Touboul C, Thomassin-Naggara I, Uzan C, You B, Daraï E. Part II drafted from the short text of the French guidelines entitled "Initial management of patients with epithelial ovarian cancer" developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY and endorsed by INCa. (Systemic and intraperitoneal treatment, elderly, fertility preservation, follow-up) Gynecol Obstet Fertil Senol. 2019 Feb;47(2):111-119 Download PDF
  • Lavoué V, Huchon C, Akladios C, Alfonsi P, Bakrin N, Ballester M, Bendifallah S, Bolze PA, Bonnet F, Bourgin C, Chabbert-Buffet N, Collinet P, Courbiere B, De la Motte Rouge T, Devouassoux-Shisheboran M, Falandry C, Ferron G, Fournier L, Gladieff L, Golfier F, Gouy S, Guyon F, Lambaudie E, Leary A, Lecuru F, Lefrere-Belda MA, Leblanc E, Lemoine A, Narducci F, Ouldamer L, Pautier P, Planchamp F, Pouget N, Ray-Coquard I, Rousset-Jablonski C, Senechal-Davin C, Touboul C, Thomassin-Naggara I, Uzan C, You B, Daraï E Management of epithelial ovarian cancer. Short text drafted from the French joint recommendations of FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY and endorsed by INCa Bull Cancer. 2019 Apr;106(4):354-370 Download PDF
  • Lavoué V, Huchon C, Akladios C, Alfonsi P, Bakrin N, Ballester M, Bendifallah S, Bolze PA, Bonnet F, Bourgin C, Chabbert-Buffet N, Collinet P, Courbiere B, De la Motte Rouge T, Devouassoux-Shisheboran M, Falandry C, Ferron G, Fournier L, Gladieff L, Golfier F, Gouy S, Guyon F, Lambaudie E, Leary A, Lecuru F, Lefrere-Belda MA, Leblanc E, Lemoine A, Narducci F, Ouldamer L, Pautier P, Planchamp F, Pouget N, Ray-Coquard I, Rousset-Jablonski C, Senechal-Davin C, Touboul C, Thomassin-Naggara I, Uzan C, You B, Daraï E Management of epithelial cancer of the ovary, fallopian tube, and primary peritoneum. Short text of the French Clinical Practice Guidelines issued by FRANCOGYN, CNGOF, SFOG, and GINECO-ARCAGY, and endorsed by INCa Eur J Obstet Gynecol Reprod Biol. 2019 May;236:214-223 Download PDF
  • Lavoué V, Huchon C, Akladios C, Alfonsi P, Bakrin N, Ballester M, Bendifallah S, Bolze PA, Bonnet F, Bourgin C, Chabbert-Buffet N, Collinet P, Courbiere B, De la Motte Rouge T, Devouassoux-Shisheboran M, Falandry C, Ferron G, Fournier L, Gladieff L, Golfier F, Gouy S, Guyon F, Lambaudie E, Leary A, Lecuru F, Lefrere-Belda MA, Leblanc E, Lemoine A, Narducci F, Ouldamer L, Pautier P, Planchamp F, Pouget N, Ray-Coquard I, Rousset-Jablonski C, Senechal-Davin C, Touboul C, Thomassin-Naggara I, Uzan C, You B, Daraï E Management of epithelial cancer of the ovary, fallopian tube, and primary peritoneum. Long text of the Joint French Clinical Practice Guidelines issued by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY, endorsed by INCa (Part 1: Diagnostic exploration and staging, surgery, perioperative care, and pathology) J Gynecol Obstet Hum Reprod. 2019 Mar 30. pii: S2468-7847(19)30143-6 Download PDF
  • Lavoué V, Huchon C, Akladios C, Alfonsi P, Bakrin N, Ballester M, Bendifallah S, Bolze PA, Bonnet F, Bourgin C, Chabbert-Buffet N, Collinet P, Courbiere B, De la Motte Rouge T, Devouassoux-Shisheboran M, Falandry C, Ferron G, Fournier L, Gladieff L, Golfier F, Gouy S, Guyon F, Lambaudie E, Leary A, Lecuru F, Lefrere-Belda MA, Leblanc E, Lemoine A, Narducci F, Ouldamer L, Pautier P, Planchamp F, Pouget N, Ray-Coquard I, Rousset-Jablonski C, Senechal-Davin C, Touboul C, Thomassin-Naggara I, Uzan C, You B, Daraï E Management of epithelial cancer of the ovary, fallopian tube, primary peritoneum. Long text of the joint French clinical practice guidelines issued by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY, endorsed by INCa. (Part 2: systemic, intraperitoneal treatment, elderly patients, fertility preservation, follow-up) J Gynecol Obstet Hum Reprod. 2019 Mar 29. pii: S2468-7847(19)30144-8 Download PDF
  • Lemoine A, Lambaudie E, Bonnet F, Leblanc E, Alfonsi P Perioperative care of epithelial ovarian cancer: Article drafted from the French Guidelines in oncology entitled "Initial management of patients with epithelial ovarian cancer" developed by FRANCOGYN, CNGOF, SFOG, GINECO-ARCAGY under the aegis of CNGOF and endorsed by INCa Gynecol Obstet Fertil Senol. 2019 Feb;47(2):187-196 Download PDF
  • Le Rhun E, von Achenbach C, Lohmann B, Silginer M, Schneider H, Meetze K, Szabo E, Weller M Profound, durable and MGMT-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibitionInt J Cancer. 2019 Jul 1;145(1):242-253 Download PDF
  • Le Rhun E, Devos P, Boulanger T, Smits M, Brandsma D, Rudà R, Furtner J, Hempel JM, Postma TJ, Roth P, Snijders TJ, Winkler F, Winklhofer S, Castellano A, Hattingen E, Capellades J, Gorlia T, van den Bent M, Wen PY, Bendszus M, Weller M European Organisation for Research and Treatment of Cancer (EORTC) Brain Tumor Group (BTG) Central Nervous System (CNS) Metastases Committee and the EORTC BTG Imaging Committee. The RANO Leptomeningeal Metastasis Group proposal to assess response to treatment: lack of feasibility and clinical utility, and a revised proposal Neuro Oncol. 2019 Jan 23. doi: 10.1093/neuonc/noz024 Download PDF
  • Risoud M, Bonne NX, Vincent C Anaplastic lymphoma and silicone in cochlear implants: Let's reassure Eur Ann Otorhinolaryngol Head Neck Dis Oct;136(5):339. doi: 10.1016/j.anorl.2019.04.015 Download PDF
  • Seoane J, De Mattos-Arruda L, Le Rhun E, Bardelli A, Weller M Cerebrospinal fluid cell-free tumour DNA as a liquid biopsy for primary brain tumours and central nervous system metastases Ann Oncol. 2019 Feb 1;30(2):211-218 Download PDF
  • Ursu R, Thomas L, Psimaras D, Chinot O, Le Rhun E, Ricard D, Charissoux M, Cuzzubbo S, Sejalon F, Quillien V, Hoang-Xuan K, Ducray F, Portal JJ, Tibi A, Mandonnet E, Levy-Piedbois C, Vicaut E, Carpentier AF Angiotensin II receptor blockers, steroids and radiotherapy in glioblastoma-a randomised multicentre trial (ASTER trial) An ANOCEF study Eur J Cancer. 2019 Mar;109:129-136 doi.org/10.1016/j.ejca.2018.12.025 Download PDF
  • Weller M, Le Rhun E Immunotherapy for glioblastoma: quo vadis ? Nat Rev Clin Oncol. 2019 Mar 13. doi: 10.1038/s41571-019-0195-3 Download PDF

Fundamentals

  • Brunet MA, Brunelle M, Lucier JF, Delcourt V, Levesque M, Grenier F, Samandi S, Leblanc S, Aguilar JD, Dufour P, Jacques JF, Fournier I, Ouangraoua A, Scott MS, Boisvert FM, Roucou X OpenProt : a more comprehensive guide to explore eukaryotic coding potential and proteomes Nucleic Acids Res. 2018 Oct 9. doi: 10.1093/nar/gky936 Download PDF
  • Cizkova D, Cubinkova V, Smolek T, Murgoci AN, Danko J, Vdoviakova K, Humenik F, Cizek M, Quanico J, Fournier I, Salzet M Localized Intrathecal Delivery of Mesenchymal Stromal Cells Conditioned Medium Improves Functional Recovery in a Rat Model of Spinal Cord Injury. Int J Mol Sci. 15;19(3). pii: E870 Download PDF
  • Delcourt V, Franck J, Quanico J, Gimeno JP, Wisztorski M, Raffo Romero A, Kobeissy F, Roucou X, Salzet M, Fournier I Top-down microproteomics bridged to MALDI MS imaging reveals the molecular physiome of brain regions. Molecular & Cellular Protemics 2018 17(2):357-372 Download PDF
  • Delcourt V, Brunelle M, Roy AV, Jacques JF, Salzet M, Fournier I, Roucou X The protein coded by a short open reading frame, not by the annotated coding sequence is the main gene product of the dual-coding gene MIEF1 Mol Cell Proteomics. 2018 Sep 4. pii: mcp.RA118.000593 Download PDF
  • Delcourt V, Staskevicius A, Salzet M, Fournier I, Roucou X Small Proteins Encoded by Unannotated ORFs are Rising Stars of the Proteome, Confirming Shortcomings in Genome Annotations and Current Vision of an mRNA. Proteomics 2018, ;18(10):21700058 Download PDF
  • Delcourt V, Brunelle M, Roy AV, Jacques JF, Salzet M, Fournier I, Roucou X First evidence that a protein coded by a short ORF, not by the annotated CDS is the main gene product. Molecular and Cellular Proteomics Download PDF
  • Duhamel M, Rose M, Rodet F, Murgoci AN, Zografidou L, Régnier-Vigouroux A, Vanden Abeele F, Kobeissy F, Nataf S, Pays L, Wisztorski M, Fournier I, Salzet M Paclitaxel Treatment and Proprotein Convertase 1/3 (PC1/3) Knockdown in Macrophages is a Promising Antiglioma Strategy as Revealed by Proteomics and Cytotoxicity Studies. Molecular and Cellular Proteomics 2018 Jun;17(6):1126-1143 Download PDF
  • Giudetti AM, Salzet M, Cassano T Oxidative Stress in Aging Brain: Nutritional and Pharmacological Interventions for Neurodegenerative Disorders. Oxid Med Cell Longev. 11;2018:3416028 Download PDF
  • Fatou B, Saudemont P, Duhamel M, Ziskind M, Focsa C, Salzet M, Fournier I Real time and in vivo Pharmaceutical and Environmental studies with SpiderMass instrument J Biotechnol. 2018 Sep 10;281:61-66. doi: 10.1016/j.jbiotec.2018.06.339. Epub 2018 Jun 20 Download PDF
  • Fatou B, Quanico J, Ziskind M, Focsa C, Salzet M, Fournier I, Remote Atmospheric Pressure Infrared Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry of Proteins. Mol. Cell. Proteomics. doi: 10.1074/mcp TIR117 000582 Download PDF
  • Fournier I, Saudemont P, Quanico J, Fatou B, Minier K, Pottier M, Bouchaert E, Pascal Q, Focsa C, Ziskind M, Tierny D, Salzet M Can real time molecular analyses change the paradigm of dog sarcoma diagnosis and classification ? Journal of Biotechnology 280, S4 doi.org/10.1016/j.jbiotec.2018.06.315 Download PDF
  • Mallah K, Quanico J, Kobeissy F, Zibara K, Salzet M, Fournier I Temporally and spatially-resolved microproteomics and MALDI MSI lipidomic analysis for traumatic brain injury biomarker identification Journal of Biotechnology 280, S8 doi: 10.1016/j.jbiotec.2018.06.327 Download PDF
  • Mallah K, Quanico J, Trede D, Kobeissy F, Zibara K, Salzet M, Fournier I Lipid Changes Associated with Traumatic Brain Injury Revealed by 3D MALDI-MSI Anal Chem. 2018, 90(17):10568-10576. 74 Download PDF
  • Mondello S, Thelin EP, Shaw G, Salzet M, Visalli C, Cizkova D, Kobeissy F, Buki A, Extracellular vesicles: pathogenetic, diagnostic and therapeutic value in traumatic brain injury. Expert Rev Proteomics. 2018, 15(5):451-461 Download PDF
  • Murgoci AN, Cizkova D, Majerova P, Petovova E, Mevecky L, Fournier I, Salzet M Brain-Cortex Microglia-Derived Exosomes: Nanoparticles for Glioma Therapy Chem PhysChem 22;19(10):1205-1214 doi: 10.1002 cphc 201701198. Epub 2018 Feb 19 Download PDF
  • Quanico J, Hauberg-Lotte L, Devaux S, Laouby Z, Meriaux C, Raffo-Romero A, Rose M, Westerheide L, Vehmeyer J, Rodet F, Maass P, Cizkova D, Zilka N, Cubinkova V, Fournier I Salzet M 3D MALDI mass spectrometry imaging reveals specific localization of long-chain acylcarnitines within a 10-day time window of spinal cord injury Sci Rep. 2018 Oct 31;8(1):16083 Download PDF
  • Raffo-Romero A, Arab T, Issa S. Al-Amri, Le Marrec-Croq F, Van Camp C, Lemaire Q, Salzet M, Vizioli J, Sautiere PE, Lefebvre C Medicinal Leech CNS as a Model for Exosome Studies in the Crosstalk between Microglia and Neurons International Journal of Molecular Sciences Download PDF
  • Salzet M, Quanico J, Cizkova D, Karnoub MA, Laouby Z, Mériaux C Shedding new light on spinal cord injury Journal of Biotechnology 280, S4 Download PDF
  • Saponaro C, Sergio S, Coluccia A, De Luca M, La Regina G, Mologni L, Famiglini V, Naccarato V, Bonetti D, Gautier C, Gianni S, Vergara D, Salzet M, Fournier I, Bucci C, Silvestri R, Gambacorti, Passerini C, Maffia M, Coluccia A A novel PDZ1-domain ligand antagonist of NHERF1 overcomes the resistance to oncogenic ß-Catenin targeting in colorectal cancer cells β-catenin knockdown promotes NHERF1-mediated survival of colorectal cancer cells: implications for a double-targeted therapy. Oncogene Download PDF
  • Saudemont P, Quanico J, Fatou B, Tierny D, Pascal Q, Minier K, Pottier M, Focsa C, Takats Z, Ziskind M, Salzet M, Fournier I Real-time molecular diagnosis and margin definition of tumors based on a novel laser-based mass spectrometry technology Cancer Cell 2018, 34(5):840-851 Download PDF
  • Simeone P, Trerotola M, Franck J, Tristan C, Marchisio M, Fournier I, Salzet M, Maffia M, Vergara D The multiverse nature of epithelial to mesenchymal transition Semin Cancer Biol. 2018 Nov 16. pii: S1044-579X(18)30086-5. doi: 10.1016/j.semcancer.2018.11.004 Download PDF
  • Théry C, Witwer K.W, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM et al Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018 Nov 23;7(1):1535750 Download PDF
  • Vergara D, Romano A, Stanca E, La Pesa V, Aloisi L, De Domenico S, Franck J, Cicalini I, Giudetti A, Storelli E, Pieragostino D, Fournier I, Sannino A, Salzet M, Cerri F, Quattrini A, Maffia M Proteomic expression profile of injured rat peripheral nerves revealed biological networks and processes J Cell Physiol. 233(8):6207-6223 Download PDF

Clinicals

  • Bonneau C, Paintaud G, Dubot C, Desvignes C, Le Rhun E, Trédant O, Dieras V, Taillibert S, Tresca P, Turbiez I, Li J, Passot C, Mefti F, Fourme E, Gutierrez M Phase I feasibility study for intrathecal administration of trastuzumab in patients with HER2 positive breast carcinomatous meningitis. Eur J Cancer 95:75-84 Download PDF
  • Dirven L, Armstrong TS, Blakeley JO, Brown PD, Grant R, Jalali R, Leeper H, Mendoza T, Nayak L, Reijneveld JC, Le Rhun E, Walbert T, Weller M, Wen PY, Taphoorn MJB Working plan for the use of patient-reported outcome measures in adults with brain tumours: a Response Assessment in Neuro-Oncology (RANO) initiative Lancet Oncol 19(3):e173-e180 Download PDF
  • Gauvain C, Vauléon E, Chouaid C, Le Rhun E, Jabot L, Scherpereel A, Vinas F, Cortot AB, Monnet I Intracerebral efficacy and tolerance of nivolumab in non-small-cell lung cancer patients with brain metastases Lung Cancer. 2018 Feb;116:62-66. doi: 10.1016/j.lungcan.2017.12.008 Download PDF
  • Girard E, Lacour A, Abi Rached H, Ramdane N, Templier C, Dziwniel V, Desmedt E, Le Rhun E, Mortier L Occurrence of vismodegib-induced cramps (muscular spasms) in the treatment of basal cell carcinoma: A prospective study in 30 patients Am Acad Dermatol. 2018 Jun;78(6):1213-1216.e2 Download PDF
  • Huang RY, Unadkat P, Linda Bi W, George E, Preusser M, McCracken DJ, Keen JR, Read WL, Olson JJ, Seystahl K, Le Rhun E, Roelcke U, Koeppen S, Furtner J, Weller M, Raizer JJ, Schiff D, Wen PY Response Assessment of Meningioma: 1D, 2D and Volumetric Criteria for Treatment Response and Tumor Progression Neuro Oncol. 2018 Aug 2. doi: 10.1093/neuonc/noy 126 Download PDF
  • Le Rhun E, Gorlia T. Farewell to monomodality treatment in patients with WHO lower grade glioma ? Eur J Cancer. 2018 Jan;88:109-114 Download PDF
  • Le Rhun E, Genbrugge E, Stupp R, Chinot OL, Nabors LB, Cloughesy T, Reardon DA, Wick W, Gorlia T, Weller M Associations of anticoagulant use with outcome in newly diagnosed glioblastoma.Eur J Cancer. 2018 Sep;101:95-104 Download PDF
  • Leroy HA, Delmaire C, Le Rhun E, Drumez E, Lejeune JP, Reyns N High-field intraoperative MRI in glioma surgery: A prospective study with volumetric analysis of extent of resection and functional outcome Neurochirurgie. 2018 Jun;64(3):155-160. doi: 10.1016/j.neuchi.2018.02.003 Download PDF
  • Lefranc F, Le Rhun E, Kiss R, Weller M Glioblastoma quo vadis: Will migration and invasiveness reemerge as therapeutic targets ? Cancer Treat Rev. 2018 Jul;68:145-154 Download PDF
  • Girard E, Lacour A, Abi Rached H, Ramdane N, Templier C, Dziwniel V, Desmedt E, Le Rhun E, Mortier L Occurrence of vismodegib-induced cramps (muscular spasms) in the treatment of basal cell carcinoma: A prospective study in 30 patients Am Acad Dermatol. 2018 Jun;78(6):1213-1216.e2 Download PDF
  • Reyes-Botero G, Cartalat-Carel S, Chinot OL, Barrie M, Taillandier L, Beauchesne P, Catry-Thomas I, Barrière J, Guillamo JS, Fabbro M, Frappaz D, Benouaich-Amiel A, Le Rhun E, Campello C, Tennevet I, Ghiringhelli F, Tanguy ML, Mokhtari K, Honnorat J, Delattre JY Temozolomide Plus Bevacizumab in Elderly Patients with Newly Diagnosed Glioblastoma and Poor Performance Status: An ANOCEF Phase II Trial (ATAG) Oncologist. 2018 May;23(5):524-e44 Download PDF
  • Samouëlian V, Mechtouf N, Leblanc E, Cardin GB, Lhotellier V, Querleu D, Révillion F, Rodier F Sensitive molecular detection of small nodal metastasis in uterine cervical cancer using HPV16-E6/CK19/MUC1 cancer biomarkers Oncotarget Apr 24;9(31):21641-21654 Download PDF
  • Valiente M, Ahluwalia MS, Boire A, Brastianos PK, Goldberg SB, Lee EQ, Le Rhun E, Preusser M, Winkler F, Soffietti R The Evolving Landscape of Brain Metastasis Trends Cancer 2018 Mar;4(3):176-196
  • Wolpert F, Weller M, A.S. Berghoff AS, E. Rushing E, L.M. Füreder LM, Petyt G, Leske H, Andratschke N, Regli L, Neidert MC, Stupp R, Stahel R, Dummer R,  Frauenfelder T, Roth P, Reyns N, Kaufmann PA Preusser M, Le Rhun E. Diagnostic value of 18F-fluordesoxyglucose positron emission tomography (FDG)-PET/CT for patients with brain metastasis from unknown primary site. Eur J Cancer ;96:64-72 Download PDF

Fundamentals

  • Delcourt V, Staskevicius A, Salzet M, Fournier I, Roucou XSmall proteins encoded by unannotated ORFs are rising stars of the proteome, confirming shortcomings in genome annotations and current vision of an mRNA Proteomics. 2017 Jun 19. doi: 10.1002/pmic.201700058 Download PDF
  • Delcourt V, Franck J, Leblanc E, Narducci F, Robin YM, Gimeno JP, Quanico J, Wisztorski M, Kobeissy F, Jacques JF, Roucou X, Salzet M, Fournier I Combined Mass Spectrometry Imaging and Top-down Microproteomics Reveals Evidence of a Hidden Proteome in Ovarian Cancer EBioMedicine. 2017 Jun 3. pii: S2352-3964(17)30229-3. doi: 10.1016/j.ebiom.2017.06.001 Download PDF
  • Devaux S, Cizkova D, Mallah K, Karnoub MA, Laouby Z, Kobeissy F, Blasko J, Nataf S, Pays L, Meriaux C, Fournier I, Salzet M RhoA inhibitor treatment at acute phase of spinal cord injury may induce neurite outgrowth and synaptogenesis Mol Cell Proteomics. 2017 Jun 28. pii: mcp.M116.064881. doi: 10.1074/mcp.M116.064881 Download PDF
  • Diologent L, Bolbach G, Focsa C, Ziskind M, Fournier I Laser induced post-desolvation of MALDI clusters International Journal of Mass Spectrometry 416 (2017) 29–36 Download PDF
  • Drago F, Lombardi M, Prada I, Gabrielli M, Joshi P, Cojoc D, Franck J, Fournier I, Vizioli J, Verderio C, ATP Modifies the Proteome of Extracellular Vesicles Released by Microglia and Influences Their Action on Astrocytes Front Pharmacol. 2017 Dec 13;8:910. doi: 10.3389/fphar.2017.00910 Download PDF
  • Le Rhun E, Duhamel M, Wisztorski M, Gimeno JP, Zairi F, Escande D, Reyns N, Kobeissy F, Maurage CA, Salzet M, Fournier I Evaluation of Non-Supervised MALDI Mass Spectrometry Imaging Combined to MicroProteomics for Glioma Grade III Classification Biochim Biophys Acta. 2017 Jul;1865(7):875-890. doi: 10.1016 j bbapap 2016.11.012. Epub 2016 Nov 24 Download PDF
  • Quanico J, Franck J, Wisztorski M, Salzet M, Fournier I Integrated Mass Spectrometry Imaging and Omics Workflows on the Same Tissue Section Using Parafilm-Assisted Microdissection Biochim Biophys Acta. 2017 Jul;1861(7):1702-1714. doi: 10.1016/j.bbagen.2017.03.006. Epub 2017 Mar 11 Download PDF
  • Quanico J, Franck J, Wisztorski M, Salzet M, Fournier I Combined MALDI Mass Spectrometry Imaging and Parafilm-Assisted Microdissection-Based LC-MS/MS Workflows in the Study of the Brain Methods Mol Biol. 2017;1598:269-283. doi: 10.1007/978-1-4939-6952-4_13 Link article
  • Quanico J, Franck J, Wisztorski M, Salzet M, Fournier I Progress and potential of imaging mass spectrometry applied to biomarker discovery Methods Mol Biol. 2017;1598:21-43. doi: 10.1007/978-1-4939-6952-4_2 Link article
  • Quanico J, Gimeno JP, Nadal-Wollbold F, Casas C, Alvares-Georges S, Redoules D, Schmitt AM, Fournier I, Salzet M Proteomic and transcriptomic investigation of acne vulgaris microcystic and papular lesions: Insights in the understanding of its pathophysiology Biochim Biophys Acta. 2017 Mar;1861(3):652-663. doi: 10.1016/j.bbagen.2016.10.021. Epub 2016 Oct 24 Download PDF
  • Quanico J, Franck J, Cardon T, Leblanc E, Wisztorski M, Salzet M, Fournier I NanoLC-MS coupling of liquid microjunction microextraction for on-tissue proteomic analysis Biochim Biophys Acta. 2017 Jul;1865(7):891-900. doi: 10.1016/j.bbapap.2016.11.002. Epub 2016 Nov 9 Download PDF
  • Rizzello A, Franck J, Pellegrino M, De Nuccio F, Simeone P, Fiore G, Di Tommaso S, Malvasi A, Tinelli A, Fournier I, Salzet M, Maffia M, Vergara D A proteomic analysis of human uterine myoma Current Protein and Peptide Science 18, 167-174
  • Samandi S, V Roy A, Delcourt V, Lucier JF, Gagnon J, C Beaudoin M, Vanderperre B, Breton MA, Jacques JF, Brunelle M, Motard J, Gagnon-Arsenault I, Fournier I, Ouangraoua A, J Hunting F, A Cohen A, R Landry C, S Scott M, Roucou X Deep transcriptome annotation suggests that small and large proteins encoded in the same genes often cooperate BioRXIV, 2017, doi: 10.1101/142992
  • Tasiemski A, Salzet M Neuro-immune lessons from an annelid : The medicinal leech Dev Comp Immunol. 2017 Jan;66:33-42. doi: 10.1016/j.dci.2016.06.026. Epub 2016 Jul 2 Download PDF
  • Trerotola M, Relli V, Tripaldi R, Sacchetti A, Havas K, Simeone P, Guerra E, Aloisi AL, La Sorda R, Lattanzio R, Vergara D, Fournier I, Salzet M, Piantelliand M, Alberti S Trop-2 activates a dormant Na+/K+-ATPase/PKCα/CD9/ezrin signaling axis to override the basal growth program of cancer cells Cancer Res July 2 2017 77 (13 Supplement) 367-367; DOI:10.1158/1538-7445.AM2017-367
  • Vergara D, Stanca E, Guerra F, Priore P, Gaballo A, Franck J, Simeone P, Trerotola M, De Domenico S, Fournier I, Bucci C, Salzet M, Giudetti AM, Maffia M β-catenin knockdown affects mitochondrial biogenesis and lipid metabolism in breast cancer cells Fontiers in Physiology ;8:544. doi: 10.3389 Download PDF
  • Wisztorski M, Quanico J, Franck J, Fatou B, Salzet M, Fournier I Droplet-based liquid extraction for spatially-resolved microproteomics analysis of tissue sections Methods in molecular biology, pp. 49-63 Link article

Clinicals

  • Assaker R, Ritter-Lang K, Vardon D, Litrico S, Fuentes S, Putzier M, Franke J, Jarzem P, Guigui P, Nakach G, Le Huec JC Maverick total disc replacement in a real-world patient population: a prospective, multicentre, observational study European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 26, 1417 Download PDF
  • Azais H, Ghesquiere L, Petitnicolas C, Borghesi Y, Tresch-Bruneel E, Cordoba A, Narducci F, Bresson L, Leblanc E Pretherapeutic staging of locally advanced cervical cancer: Inframesenteric paraaortic lymphadenectomy accuracy to detect paraaortic metastases in comparison with infrarenal paraaortic lymphadenectomy Gynecologic oncology 147, 340-344 Download PDF
  • Baeesa S, Maghrab Y, Msadd, AK, Assaker R Quality of Spine Surgery Research from the Arab Countries: A Systematic Review and Bibliometric Analysis BioMed research international 7560236 Download PDF
  • Barca A, Vacca F, Vizioli J, Drago F, Vetrugno C, Verri T, Pagliara P Molecular and expression analysis of the Allograft inflammatory factor1 (AIF-1) in the coelomocytes of the common sea urchin Paracentrotus lividus Download PDF
  • Chamberlain M, Junck L, Brandsma D, Soffietti R, Rudà R, Raizer J, Boogerd W, Taillibert S, Groves MD, Le Rhun E, Walker J, van den Bent M, Wen PY, Jaeckle KA Leptomeningeal metastases: a RANO proposal for response criteria. Neuro Oncol. 2017 Apr 1;19(4):484-492. doi: 10.1093/neuonc/now183 Download PDF
  • Chiannilkulchai N, Pautier P, Genestie C, Bats AS, Vacher-Lavenu MC, Devouassoux-Shisheboran M, Treilleux I, Floquet A, Croce S, Ferron G, Mery E, Pomel C, Penault-Llorca F, Lefeuvre-Plesse C, Henno S, Leblanc E, Lemaire AS, Averous G, Kurtz JE, Ray-Coquard I Networking for ovarian rare tumors: a significant breakthrough improving disease management. Annals of oncology : official journal of the European Society for Medical Oncology 28, 1274-1279 Download PDF
  • Darmon I, Morisse MC, Coutte A, Blonski M, Le Rhun E, Taillandier L, Roufai DB, Desenclos C, Trudel S, Faivre JC, Blanchard N, Chauffert B, Boone M Temozolomide and Bevacizumab Induction before Chemoradiotherapy in Patients with Bulky Glioblastoma and/or with Severe Neurological Impairment Journal of Cancer 8, 1417-1 Download PDF
  • Furet E, El Bouchtaoui M, Feugeas JP, Miquel C, Leboeuf C, Beytout C, Bertheau P, Le Rhun E, Bonneterre J, Janin A, Bousquet G Increased risk of brain metastases in women with breast cancer and p16 expression in metastatic lymph-nodes. Oncotarget 8, 37332-37341 Download PDF
  • Galldiks N, Albert NL, Sommerauer M, Grosu AL, Ganswindt U, Law I, Preusser M, Le Rhun E, Vogelbaum MA, Zadeh G, Dhermain F, Weller M, Langen KJ, Tonn JC PET Imaging in Patients with Meningioma - Report of the RANO/PET Group. Neuro-oncology Download PDF
  • Kakkos A, Bresson L, Hudry D, Cousin S, Lervat C, Bogart E, Meurant JP, El Bedoui S, Decanter G, Hannebicque K, Regis C, Hamdani A, Penel N, Tresch-Bruneel E, Narducci F Complication-related removal of totally implantable venous access port systems: Does the interval between placement and first use and the neutropenia-inducing potential of chemotherapy regimens influence their incidence? A four-year prospective study of 4045 patients. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 43, 689-695 Download PDF
  • Kuchcinski G, Le Rhun E, Cortot AB, Drumez E, Duhal R, Lalisse M, Dumont J, Lopes R, Pruvo JP, Leclerc X, Delmaire C Dynamic contrast-enhanced MR imaging pharmacokinetic parameters as predictors of treatment response of brain metastases in patients with lung cancer. European radiology 27, 3733-3743 Download PDF
  • Le Rhun E, Bertrand N, Dumont A, Tresch E, Le Deley MC, Mailliez A, Preusser M, Weller M, Revillion F, Bonneterre J Identification of single nucleotide polymorphisms of the PI3K-AKT-mTOR pathway as a risk factor of central nervous system metastasis in metastatic breast cancer. European journal of cancer 87:189-198 Download PDF
  • Le Rhun E, Ruda R, Devos P, Hoang-Xuan K, Brandsma D, Perez Segura P, Soffietti R, Weller M Diagnosis and treatment patterns for patients with leptomeningeal metastasis from solid tumors across Europe Journal of neuro-oncology 133, 419-427 Download PDF
  • Le Rhun E, Taillibert S, Chamberlain MC Neoplastic Meningitis Due to Lung, Breast, and Melanoma Metastases Cancer control : journal of the Moffitt Cancer Center 24, 22-32 Download PDF
  • Le Rhun E, Weller M, Brandsma D, Van den Bent M, de Azambuja E, Henriksson R, Boulanger T, Peters S, Watts C, Wick W, Wesseling P, Ruda R, Preusser M, Board EE Committee EG, EANO-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up of patients with leptomeningeal metastasis from solid tumours Annals of oncology : official journal of the European Society for Medical Oncology 28, iv84-iv99 Download PDF
  • Makki M, Ayoub G, Abdul-Hameed H, Zairi F, Mansoor B, Nait-Abdelaziz M, Ouederni M Mullins effect in polyethylene and its dependency on crystal content: A network alteration model Journal of the mechanical behavior of biomedical materials 75, 442-454 Download PDF
  • Nicolas GN, Assaker R, Saliba C, Osman DR, Koury E, Farhat MA, Azar RR, Khoury G Foreign Body Ingestion Causing Recurrent Diverticulitis The American journal of case reports 18, 1123-1125 Download PDF
  • Pace A, Dirven L, Koekkoek JAF, Golla H, Fleming J, Ruda R, Marosi C, Le Rhun E, Grant R, Oliver K, Oberg I, Bulbeck HJ, Rooney AG, Henriksson R, Pasman HRW, Oberndorfer S, Weller M Taphoorn MJB, European Association of Neuro-Oncology palliative care task, f European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma. The Lancet. Oncology 18, e330-e340 Download PDF
  • Paldor I, Abbadi S, Bonne N, Ye X, Rodriguez FJ, Rowshanshad D, Itzoe M, Vigilar V, Giovannini M, Brem H, Blakeley JO, Tyler BM The efficacy of lapatinib and nilotinib in combination with radiation therapy in a model of NF2 associated peripheral schwannoma Journal of neuro-oncology 135, 47-56 Download PDF
  • Petitnicolas C, Azais H, Ghesquiere L, Tresch-Bruneel E, Cordoba A, Narducci F, Bresson L, Leblanc E Morbidity of Staging Inframesenteric Paraaortic Lymphadenectomy in Locally Advanced Cervical Cancer Compared With Infrarenal Lymphadenectomy International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 27, 575-580 Download PDF
  • Reich M, Girard E, Le Rhun E Breast leptomeningeal metastasis recurrence presenting as a manic episode Palliat Support Care. 2017 Apr;15(2):272-275. doi: 10.1017/S1478951516000456. Epub 2016 Jun 27
  • Remon J, Le Rhun E, Besse B, Leptomeningeal carcinomatosis in non-small cell lung cancer patients: A continuing challenge in the personalized treatment era Cancer treatment reviews 53, 128-137 Download PDF
  • Soffietti R, Abacioglu, U, Baumert B, Combs SE, Kinhult S, Kros JM, Marosi C, Metellus P, Radbruch A, Villa Freixa SS, Brada M, Carapella CM, Preusser M, Le Rhun E, Ruda R, Tonn JC, Weber DC, Weller M Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO) Neuro-oncology 19, 162-174 Download PDF
  • Tallet AV, Dhermain F, Le Rhun E, Noel G, Kirova YM Combined irradiation and targeted therapy or immune checkpoint blockade in brain metastases: toxicities and efficacy Annals of oncology : official journal of the European Society for Medical Oncology Download PDF
  • Weller M, van den Bent M, Tonn JC, Stupp R, Preusser M, Cohen-Jonathan-Moyal E, Henriksson R, Le Rhun E, Balana C, Chinot O, Bendszus M, Reijneveld JC, Dhermain F, French P, Marosi C, Watts C, Oberg I, Pilkington G, Baumert BG, Taphoorn MJB, Hegi M, Westphal M, Reifenberger G, Soffietti R, Wick W European Association for Neuro-Oncology Task Force on, G. (2017) Evidence-based management of adult patients with diffuse glioma - Authors’ reply The Lancet Oncology 18, e430-e431 Download PDF
  • Weller M, van den Bent M, Tonn JC, Stupp R, Preusser M, Cohen-Jonathan-Moyal E Henriksson R, Le Rhun E, Balana C, Chinot O, Bendszus M, Reijneveld JC, Dhermain F, French P, Marosi C, Watts C, Oberg I, Pilkington G, Baumert BG, Taphoorn MJB, Hegi M, Westphal M Reifenberger G, Soffietti R, Wick W EANO guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas Lancet Oncol. 2017 Jun;18(6):e315-e329. doi: 10.1016/S1470-2045(17)30194-8. Epub 2017 May 5 Download PDF
  • Wick W, Gorlia T, Bendszus M, Taphoorn M, Sahm F, Harting I, Brandes AA, Taal W, Domont J, Idbaih A, Campone M, Clement PM, Stupp R, Fabbro M, Le Rhun E, Dubois F, Weller M, von Deimling A, Golfinopoulos V, Bromberg JC, Platten M, Klein M, van den Bent MJ Lomustine and Bevacizumab in Progressive Glioblastoma The New England journal of medicine 377, 1954-1963 Download PDF
  • Zairi F, Nzokou A, Sunna T, Obaid S, Weil AG, Bojanowski M, Shedid D Minimally invasive costotransversectomy for the resection of large thoracic dumbbell tumors Br J Neurosurg. 2017 Apr;31(2):179-183. doi: 10.1080/02688697.2016.1233317. Epub 2016 Sep 20 Download PDF
  • Zairi F, Aboukais R, LE Rhun E, Marinho P, Maurage CA, Lejeune JP Close follow-up after discontinuation of cyproterone acetate : a possible option to defer surgery in patients with voluminous intracranial meningioma J Neurosurg Sci. 2017 Feb;61(1):98-101 Link article

Fundamentals


  • Devaux S, Cizkova D, Qunaico J, Franck J, Ntaf S, Pays L, Hauberg-Lotte L, Mass P, Hobart J.H, Kobeissy F, Merieux, C, Wisztorski M, Slovinska L, Blaska J, Cifankova V, Fournier I, Salzet M, Proteomic analysis of the spatio-temporal based molecular kinetics of acute spinal cord injury identifies a time- and segment-specific window for effective tissue repair Mol Cell Proteomics. 2016 Aug;15(8):2641-70. doi: 10.1074/mcp.M115.057794. Epub 2016 Jun 1 Download PDF
  • Duhamel M, Rodet F, Murgoci AN, Desjardins R, Gagnon H, Wisztorski M, Fournier I, Day R, Salzet M, The proprotein convertase PC1/3 regulates TLR9 trafficking and the associated signaling pathways Sci Rep. 2016 Jan 18;6:19360. doi: 10.1038/srep1936 Download PDF
  • Duhamel M, Rodet F, Murgoci A.N, Wisztorski M, Day R, Fournier I, Salzet M, Proprotein convertase 1/3 inhibited macrophages: a novel therapeutic based on drone macrophages Eupa Open Proteomic 2016, 11: 20-22 Download PDF
  • Fatou B, Saudemont P, Leblanc E, Vinatier D, Mesdag V, Wiztorski M, Focsa C, Salzet M, Ziskind M, Fournier I, SPIDERMASS: A Novel in vivo Real-Time Mass Spectrometry Based Instrument of Low Invasiveness for Guided Surgery Applications Sci Rep. 6:25919(2016) Download PDF
  • Mouilleron H, Delcourt V, Roucou X, Death of a dogma: eukaryotic mRNAs can code for more than one protein Nucleic Acids Res. 2016 Jan 8;44(1):14-23. doi: 10.1093/nar/gkv1218. Epub 2015 Nov 17 Download PDF
  • Quanico J, Franck J, Salzet M, Fournier I, On-tissue Direct Monitoring of Global Hydrogen/Deuterium Exchange by MALDI Mass Spectrometry: Tissue Deuterium Exchange Mass Spectrometry (TDXMS) Mol Cell Proteomics 2016 Oct;15(10):3321-3330. Epub 2016 Aug 10 Download PDF
  • Tissot T, Arnal A, Jacqueline C, Poulin R, Lefèvre T, Mery F, Renaud F, Roche B, Massol F, Salzet M, Ewald P, Tasiemski A, Ujvari B, Thomas F, Host manipulation by cancer cells: Expectations, facts, and therapeutic implications Bioessays 2016 Mar;38(3):276-85. doi: 10.1002/bies.201500163. Epub 2016 Feb 5 Download PDF
  • Ujvari B, Beckmann C, Biro PA, Arnal A, Tasiemski A, Massol F, Salzet M, Mery F, Boidin-Wichlacz C, Misse D, Renaud F, Vittecoq M, Tissot T, Roche B, Poulin R, Thomas F, Cancer and life-history traits: lessons from host-parasite interactions Parasitology. 2016 Apr;143(5):533-41. doi: 10.1017/S0031182016000147. Epub 2016 Feb 18 Download PDF
  • Ujvari B, Beckmann C, Arnal A, Tasiemski A, Massol F, Salzet M, Mery F, Biodin-Wichlacz C, Renaud F, Vittecoq M, Tissot T, Roche B, Poulin R, Thomas F, Cancer and life-history traits: lessons from host-parasite interactions ? Parasitology. 2016 Apr;143(5):533-41. doi: 10.1017/S0031182016000147 Download PDF
  • Vergara D, Simeone P, Frank J, Trerotola M, Tinelli A, Fournier I, Gaballo A, Saverio A, Salzet M, Maffia MD, Translating epithelial mesenchymal transition markers into the clinic: novel insights from proteomics Eupa Open Proteomic 2016, Download PDF
  • Wisztorski M, Desmons A, Quanico J, Fatou B, Gimeno JP, Franck J, Salzet M, Fournier I, Spatially-resolved protein surface microsampling from tissue sections using liquid extraction surface analysis Proteomics. 2016 Jun;16(11-12):1622-32. doi: 10.1002/pmic.201500508. Epub 2016 Apr 13 Download PDF

Clinicals

  • Aboukais R, Zairi F, Lejeune JP, Le Rhun E, Vermandel M, Blond S, Devos P, Reyns N, Response J Neurosurg 2016 Feb;124(2):584-5
  • Andrade C, Narducci F, Bresson L, Leblanc E, Boari flap ureteroneocystostomy in an oncological patient Gynecol Oncol. 2016 Oct;143(1):193. doi: 10.1016/j.ygyno.2016.07.115. PubMed PMID: 27486132 Download PDF
  • Bresson L, Allard-Duclercq C, Narducci F, Tresch E, Lesoin A, Ahmeidi A, Leblanc E, Single-port or Classic Laparoscopy Compared With Laparotomy to Assess the Peritoneal Cancer Index in Primary Advanced Epithelial Ovarian Cancer J Minim Invasive Gynecol. 2016 Jul-Aug;23(5):825-32. doi:10.1016/j.jmig.2016.03.025. PubMed PMID: 27068278
  • Frappaz D, Sunyach MP, Le Rhun E, Blonski M, Laurence V, Bonneville Levard A, Loiseau H, Meyronnet D, Callies A, Laigle-Donadey F, Faure Conter C ; au nom de l’ANOCEF, GO-AJA, de la SFCE... Adolescent and young adultes (AYAS) brain tumor national web conference. On behalf of ANOCEF, GO-AJA and SFCE societies. Bull Cancer. 2016 Nov 17. pii: S0007-4551(16)30277-6 Download PDF
  • Furtner J, Schöpf V, Seystahl K, Le Rhun E, Rudà R, Roelcke U, Koeppen S, Berghoff AS, Marosi C, Clement P, Faedi M, Watts C, Wick W, Soffietti R, Weller M, Preusser M, Kinetics of tumor size and peritumoral brain edema before, during, and after systemic therapy in recurrent WHO grade II or III meningioma Neuro Oncol. 2016 Mar;18(3):401-7 Download PDF
  • Hohnen R, Rahnama’i MS, van Gink M, van Koeveringe GA, Meriaux C, Ex vivo modulation of muscarinically induced contractions by PGE2 and an EP1 receptor antagonist in the guinea pig urinary Bladder. 2016; 3 (1) : e25
  • Kepenekian V, Elias D, Passot G, Mery E, Goere D, Delroeux D, Quenet F, Ferron G, Pezet D, Guilloit JM, Meeus P, Pocard M, Bereder JM, Abboud K, Arvieux C, Brigand C, Marchal F, Classe JM, Lorimier G, De Chaisemartin C, Guyon F, Mariani P, Ortega-Deballon P, Isaac S, Maurice C, Gilly FN, Glehen O, French Network for Rare Peritoneal Malignancies (RENAPE) Diffuse malignant peritoneal mesothelioma: Evaluation of systemic chemotherapy with comprehensive treatment through the RENAPE Database: Multi-Institutional Retrospective Study Eur J Cancer. 2016 Sep;65:69-79. doi:10.1016/j.ejca.2016.06.002 PubMed PMID:27472649 Download PDF
  • Lacorre A, Merlot B, Garabedian C, Narducci F, Chereau E, Resbeut M, Minsat M, Leblanc E, Houvenaeghel G, Lambaudie E, Early stage cervical cancer : Brachytherapy followed by type a hysterectomy versus type B radical hysterectomy alone, a retrospective evaluation Eur J Surg Oncol. 2016 Mar;42(3):376-82. doi:10.1016/j.ejso.2015.12.003. PubMed PMID: 26725307 Download PDF
  • Leblanc E, Narducci F, Bresson L, Hudry D, Fluorescence-assisted sentinel (SND) and pelvic node dissections by single-port transvaginal laparoscopic surgery, for the management of an endometrial carcinoma (EC) in an elderly obese patient Gynecol Oncol. 2016 Dec;143(3):686-687 doi:10.1016/j.ygyno.2016.10.010. PubMed PMID: 27745919 Download PDF
  • Leblanc E, Katdare N, Narducci F, Bresson L, Gouy S, Morice P, Ferron G, Querleu D, Martinez A, Should Systematic Infrarenal Para-aortic Dissection Be the Rule in the Pretherapeutic Staging of Primary or Recurrent Locally Advanced Cervix Cancer Patients With a Negative Preoperative Para-aortic PET Imaging ? Int J Gynecol Cancer. 2016 Jan;26(1):169-75. doi: 10.1097/IGC.0000000000000588 PubMed PMID: 26569062 Download PDF
  • Le Rhun E., Taillibert S., Chamberlain MC, Current Management of Adult Diffuse Infiltrative Low Grade Gliomas Curr Neurol Neurosci Rep. 2016 Feb;16(2):15. doi: 10.1007/s11910-015-0615-4 Download PDF
  • Le Rhun E, Galanis E, Leptominingeal metastases of solid cancer Curr Opin Neurol 2016 Dec;29(6):797-805 PMID:27661208 DOI:10.1097/WCO.0000000000000393 Download PDF
  • Le Rhun E, Dhermain F, Vogin G, Reyns N, Metellus P, Radionecrosis after stereotactic radiotherapy for brain metastases Expert Rev Neurother. 2016 Aug;16(8):903-14. doi: 10.1080/14737175.2016.1184572. Epub 2016 May 17
  • Le Rhun E, Taillibert S, Chamberlain MC, Systemic therapy for recurrent meningiom Expert Rev Neurother. 2016 Aug;16(8):889-901. doi: 10.1080/14737175.2016.1184087. Epub 2016 May 19
  • Le Rhun E, Perry JP, Vascular complications in glioma patients Handb Clin Neurol. 2016;134:251-66. doi: 10.1016/B978-0-12-802997-8.00015-3
  • Martinez A, Ngo C, Leblanc E, Gouy S, Luyckx M, Darai E, Classe JM, Guyon F, Pomel C, Ferron G, Filleron T, Querleu D, Surgical Complexity Impact on Survival After Complete Cytoreductive Surgery for Advanced Ovarian Cancer Ann Surg Oncol. 2016 Aug;23(8):2515-21. doi: 10.1245/s10434-015-5069-z. PubMed PMID: 27008588 Download PDF
  • Meghelli L, Narducci F, Mariette C, Piessen G, Vanseymortier M, Leblanc E, Collinet P, Duhamel A, Penel N, Reporting adverse events in cancer surgery randomized trials: A systematic review of published trials in oesophago-gastric and gynecological cancer patients Crit Rev Oncol Hematol. 2016 Aug;104:108-14.doi: 10.1016/j.critrevonc.2016.05.017. Review. PubMed PMID: 27323658 Download PDF
  • Nayama M, Collinet P, Salzet M, Vinatier D, Immunological aspects of ovarian cancer: Therapeutic perspectives J Gynecol Obstet Biol Reprod (Paris) (2016) Jun 16. pii: S0368-2315(16)30037-0 Download PDF
  • Taillibert S, Le Rhun E, Chamberlain MC, Chemotherapy-Related Neurotoxicity Curr Neurol Neurosci Rep. 2016 Sep;16(9):81. doi: 10.1007/s11910-016-0686-x Download PDF
  • Rizzello A, Franck J, Pellegrino M, De Nuccio F, Simeone P, Fiore G, Di Tommaso S, Malvasi A, Tinelli A, Fournier I, Salzet M, Maffia M, Vergara D, A proteomic analysis of human uterine myoma Curr Protein Pept Sci. 2016;18(2):167-174. doi: 10.2174/1389203717666160322150603
  • Simon N, Vasseur M, Chauffert B, Taillandier L, Le Rhun E, Systemic therapies administration for adult patients in neuro-oncology : The standards of the Association of the neuro-oncologists of French expression (ANOCEF) Bull Cancer. 2016 Apr;103(4):400-1. doi: 10.1016/j.bulcan.2016.01.011. Epub 2016 Feb 10 Download PDF
  • Vidal F, Guerby P, Luyckx M, Haddad P, Stoeckle E, Morice P, Leblanc E, Lecuru F, Daraï E, Classe JM, Pomel C, Filleron T, Ferron G, Querleu D, Rafii A, Are Early Relapses in Advanced-Stage Ovarian Cancer Doomed to a Poor Prognosis ? PLoS One. 2016 Jan 28;11(1):e0147787 doi:10.1371/journal.pone.0147787 PubMed PMID:26820579; PubMed Central PMCID: PMC4731146 Download PDF
  • Zairi F, Karnoub MA, Vieillard MH, Bouras A, Marinho P, Allaoui M, Devos P, Assaker R, Evaluation of the relevance of surgery in a retrospective case series of patients who underwent the surgical treatment of a symptomatic spine metastasis from lung cancer Eur Spine J. 2016 Dec;25(12):4052-4059. Epub 2016 Jan 28 Download PDF

Fundamentals

  • Cizkova D, Slovinska L, Grulova I, Nagyova M, Salzet M, Cikos S, Kryukov O, Cohen S, J. Tissue Eng. Reg. Med. 2015, 9: 918–929 The influence of sustained dual factor presentation on the expansion and differentiation of neural progenitors in affinity-binding alginate scaffolds Tissue Eng Regen Med. 2015 Aug;9(8):918-29. doi: 10.1002/term.1797. Epub 2013 Aug 16 Download PDF
  • Demeyer M, Wisztorski M, Decroo C, De Winter J, Caulier G, Hennebert E, Eeckhaut I, Fournier I, Flammang P, Gerbaux P, Inter- and intra-organ spatial distributions of sea star saponins by MALDI imaging Anal Bioanal Chem. 2015 Nov;407(29):8813-24. doi: 10.1007/s00216-015-9044-0. Epub 2015 Sep 28 Download PDF
  • Duhamel M, Rodet F, Delhem N, Vanden Abeele F, Kobeissy F, Nataf S, Pays L, Desjardins R, Gagnon H,Wisztorski M, Fournier I, Day R, Salzet M, Molecular Consequences of Proprotein Convertase 1/3 (PC1/3) Inhibition in Macrophages for Application to Cancer Immunotherapy: A Proteomic Study Mol Cell Proteomics. 2015 Nov;14(11):2857-77. doi: 10.1074/mcp.M115.052480. Epub 2015 Sep 1 Download PDF
  • Fatou B, Wisztorski M, Focsa C, Salzet M, Ziskind M, Fournier I, Substrate-Mediated Laser Ablation under Ambient Conditions for Spatially-Resolved Tissue Proteomics Sci Rep. 2015 Dec 17;5:18135. doi: 10.1038/srep18135 Download PDF
  • Grulova I, Slovinska L, Blaško J, Devaux S, Wisztorski M, Salzet M, Fournier I, Kryukov O, Cohen S, Cizkova D, Delivery of Alginate Scaffold Releasing Two Trophic Factors for Spinal Cord Injury Repair Sci Rep. 2015 Sep 8;5:13702. doi: 10.1038/srep13702 Download PDF
  • Ho Kim J, Franck J, Kang T, Heinsen H, Ravid R, Ferrer I, Hee Cheon M, Lee JY, Shin Yoo J, Steinbusch HW, Salzet M, Fournier I, Mok Park Y, Proteome-wide characterization of signalling interactions in the hippocampal CA4/DG subfield of patients with Alzheimer’s disease Sci Rep. 2015 Jun 10;5:11138. doi: 10.1038/srep11138 Download PDF
  • Kopp C, Wisztorski M, Revel J, Mehiri M, Dani V, Capron L, Carette D, Fournier I, Massi L, Mouajjah D, Pagnotta S, Priouzeau F, Salzet M, Meibom A, Sabourault C, NanoSIMS and MALDI-MS Imaging techniques to study cnidarian dinoflagellate symbiosis Zoology (Jena). 2015 Apr;118(2):125-31. doi: 10.1016/j.zool.2014.06.006. Epub 2014 Oct 5 Download PDF
  • Quanico J, Franck J, Gimeno J.P, Sabbagh R, Salzet M, Day R, Fournier I, Parafilm-Assisted Microdissection: A Sampling Method for Mass Spectrometry-Based Identification of Differentially Expressed Prostate Cancer Protein Biomarkers Chem Commun (Camb). 2015 Mar 18;51(22):4564-7. doi: 10.1039/c4cc08331h Download PDF
  • Rodet F., Tasiemski A., Boidin-Wichlacz C., Vuillaume C., Slomianny C., Salzet M, Hm-MyD88 and Hm-SARM: Two key regulators of the neuroimmune system and neural repair in the medicinal leech Sci Rep. 2015 Apr 16;5:9624. doi: 10.1038/srep09624 Download PDF
  • Schorn T, Drago F, Tettamanti G, Valvassori R, de Eguileor M, Vizioli J, Grimaldi A, Homolog of allograft inflammatory factor-1 induces macrophage migration during innate immune response in leech Cell Tissue Res. 2015 Mar;359(3):853-64. doi: 10.1007/s00441-014-2058-7. Epub 2014 Dec 2 Download PDF
  • Slovinska L., Szekiova E., Blasko J., Devaux S., Salzet M., Cizkova D, Comparison of dynamic behavior and maturation of neural multipotent cells derived from different spinal cord developmental stages: an in vitro study Acta Neurobiol Exp (Wars) 2015, 75(1):107-14 Download PDF
  • Tasiemski A, Massol F, Cuvillier-Hot V, Boidin-Wichlacz C, Roger E, Rodet F, Fournier I, Thomas F, Salzet M, Reciprocal immune benefit based on complementary production of antibiotics by the leech Hirudo verbana and its gut symbiont Aeromonas veronii Sci Rep. 2015 Dec 4;5:17498. doi: 10.1038/srep17498 Download PDF

Clinicals

  • Aboukais R, Assaker R, Karnoub MA, Zairi F, Delayed Hypersensitivity Reaction ; An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement Case Rep Orthop. 2015;2015:416548. doi: 10.1155/2015/416548. Epub 2015 Aug 9 Download PDF
  • Aboukais R, Zairi F, Le Rhun E, Lejeune JP, Devos P, Reyns N, Radiation-associated grade 2 meningiomas: A nine patient-series and review of the literature Clin Neurol Neurosurg. 2015 Sep;136:10-4. doi: 10.1016/j.clineuro.2015.05.022. Epub 2015 May 27 Download PDF
  • Aboukais R, Zairi F, Lejeune JP, Le Rhun E, Vermandel M, Blond S, Devos P, Reyns N, Grade 2 meningioma and radiosurgery J Neurosurg. 2015 May;122(5):1157-62 Download PDF
  • Allaoui M, Assaker R, Grelat M, Marinho P, Quidet M, Zairi F, Assessment of the surgeon radiation exposure during a minimally invasive TLIF : Comparison between fluoroscopy and O-arm system Neurochirurgie. 2015 Aug;61(4):255-9. doi: 10.1016/j.neuchi.2015.04.002. Epub 2015 Jun 10 Download PDF
  • Arsène E, Bleu G, Merlot B, Boulanger L, Vinatier D, Kerdraon O, Collinet P, Implications of a two-step procedure in surgical management of patients with early-stage endometrioid endometrial cancer J Gynecol Oncol. 2015 Apr;26(2):125-33. doi: 10.3802/jgo.2015.26.2.125 Download PDF
  • Assaker R, Vieillard MH, Zairi F, Spine metastases : are minimally invasive surgical techniques living up to the hype ? CNS Oncol. 2015;4(4):257-64. doi: 10.2217/cns.15.15. Epub 2015 Jun 22 Download PDF
  • Assaker R, Ritter-Lang K, Vardon D, Litrico S, Fuentes S, Putzier M, Franke J, Jarzem P, Guigui P, Nakach G, Le Huec JC, Maverick total disc replacement in a real-world patient population: a prospective, multicentre, observational study Eur Spine J. 2015 Sep;24(9):2047-55. doi: 10.1007/s00586-015-3918-x. Epub 2015 Jun 7 Download PDF
  • Bleu G, Arsène E, Merlot B, Kerdraon O, Bigot J, Boulanger L, Dedet B, Vinatier D, Collinet P, How to improve the preoperative staging of presumed early-stage endometrioid endometrial cancer ? Eur J Gynaecol Oncol. 2015;36(6):698-702
  • Cordoba A, Nickers P, Tresch E, Castelain B, Leblanc E, Narducci F, Le Tinier F, Lesoin A, Lacornerie T, Lartigau E, Safety of adjuvant intensity-modulated postoperative radiation therapy in endometrial cancer: Clinical data and dosimetric parameters according to the International Commission on Radiation Units (ICRU) 83 report. Rep Pract Oncol Radiother. 2015 Sep-Oct;20(5):385-92. doi: 10.1016/j.rpor.2015.06.002. PubMed PMID: 26549997; PubMed Central PMCID: PMC4597088 Download PDF
  • Cortés J, Dieras V, Ro J, Barriere J, Bachelot T, Hurvitz S, Le Rhun E, Espié M, Kim SB, Schneeweiss A, Sohn JH, Nabholtz JM, Kellokumpu-Lehtinen PL, Taguchi J, Piacentini F, Ciruelos E, Bono P, Ould-Kaci M, Roux F, Joensuu H, Afatinib alone or afatinib plus vinorelbine versus investigator’s choice of treatment for HER2-positive breast cancer with progressive brain metastases after trastuzumab, lapatinib, or both (LUX-Breast 3): a randomised, open-label, multicentre, phase 2 trial Lancet Oncol. 2015, 16(16):1700-10 Download PDF
  • Dansin E, Carnot A, Servent V, Daussay D, Robin YM, Surmei-Pintilie E, Lauridant G, Descarpentries C, Révillion F, Delattre C, EGFR-Mutated Breast Metastasis of Lung Adenocarcinoma: A Case Report Case Rep Oncol. 2015 Mar 14;8(1):164-8. doi: 10.1159/000381014. eCollection 2015 Jan-Apr Download PDF
  • Daraï E, Dubernard G, Bats AS, Heitz D, Mathevet P, Marret H, Querleu D, Golfier F, Leblanc E, Rouzier R, Ballester M, Sentinel node biopsy for the management of early stage endometrial cancer: long-term results of the SENTI-ENDO study Gynecol Oncol. 2015 Jan;136(1):54-9. doi: 10.1016/j.ygyno.2014.09.011. Epub 2014 Oct 22 Download PDF
  • Delmaire C, Savatovsky J, Boulanger T, Dhermain F, Le Rhun E, Météllus P, Gerber S, Carsin-Nicole B, Petyt G, Brain metastases imaging Cancer Radiother. 2015 Feb;19(1):16-9. doi: 10.1016/j.canrad.2014.11.008. Epub 2015 Jan 31 Download PDF
  • Demeyer M, Wisztorski M, Decroo C, De Winter J, Caulier G, Hennebert E, Eeckhaut I, Fournier I, Flammang P, Gerbaux P, Inter and intra organ spatial distributions of sea star saponins by MALDI imaging Anal Bioanal Chem. 2015 Nov;407(29):8813-24. doi: 10.1007/s00216-015-9044-0. Epub 2015 Sep 28 Download PDF
  • Franké O, Narducci F, Chereau-Ewald E, Orsoni M, Jauffret C, Leblanc E, Houvenaeghel G, Lambaudie E, Role of a Double Docking to Improve Lymph Node Dissection: When Robotically Assisted Laparoscopy for Para-aortic Lymphadenectomy Is Associated to a Pelvic Procedure Int J Gynecol Cancer. 201525(2): 331-6
  • Garabedian C, Merlot B, Bresson L, Tresch E, Narducci F, Leblanc E, Minimally Invasive Surgical Management of Early-Stage Cervical Cancer: An Analysis of the Risk Factors of Surgical Complications and of Oncologic Outcomes Int J Gynecol Cancer. 2015 May;25(4):714-21. doi: 10.1097/IGC.0000000000000390
  • Grelat M, Zairi F, Quidet M, Marinho P, Allaoui M, Assaker R, Assessment of the surgeon radiation exposure during a minimally invasive TLIF: Comparison between fluoroscopy and O-arm system Neurochirurgie. 2015 Aug;61(4):255-9. doi: 10.1016/j.neuchi.2015.04.002. Epub 2015 Jun 10 Download PDF
  • Hanssens S, Rubod C, Kerdraon O, Vinatier D, Lucot JP, Duhamel A, Collinet P, Pelvic endometriosis in women under 25: a specific management ? Minerva Med. 2015 Jun;106(3):123-31. Epub 2014 Oct 6
  • Karnoub MA, Zairi F, Aboukais R, Assaker R, Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement Case Rep Orthop. 2015;2015:416548. doi: 10.1155/2015/416548. Epub 2015 Aug 9 Download PDF
  • Le Rhun E, Chamberlain MC, Zairi F, Delmaire C, Idbaih A, Renaud F, Maurage CA, Grégoire V, Patterns of response to crizotinib in recurrent glioblastoma according to ALK and MET molecular profile in two patients CNS Oncol. 2015;4(6):381-6. doi: 10.2217/cns.15.30. Epub 2015 Oct 26 Download PDF
  • Le Rhun E, Delbeuck X, Lefeuvre-Plesse C, Kramar A, Skrobala E, Pasquier F, Bonneterre J, A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy Breast Cancer Res Treat. 2015 Aug;152(3):569-80. doi: 10.1007/s10549-015-3493-1. Epub 2015 Jul 11 Download PDF
  • Le Rhun E, Taillibert S, Chamberlain MC, Anaplastic glioma: current treatment and management Expert Rev Neurother. 2015 Jun;15(6):601-20. doi: 10.1586/14737175.2015.1042455. Epub 2015 May 2 Download PDF
  • Le Rhun E, Taillibert S, Chamberlain MC, The future of high-grade glioma: Where we are and where are we going Surg Neurol Int. 2015 Feb 13;6(Suppl 1):S9-S44. doi: 10.4103/2152-7806.151331. eCollection 2015 Download PDF
  • Le Rhun E, Taillibert S, Boulanger T, Zairi F, Bonneterre J, Chamberlain MC, Prolonged Response and Restoration of Functional Independence with Bevacizumab plus Vinorelbine as Third-Line Treatment for Breast Cancer-Related Leptomeningeal Metastases Case Rep Oncol. 2015 Feb 12;8(1):72-7. doi: 10.1159/000375293. eCollection 2015 Jan-Apr Download PDF
  • Le Rhun E, Dhermain F, Noël G, Reyns N, Carpentier A, Mandonnet E, Taillibert S, Metellus P, ANOCEF l’Association des neuro-oncologues d’expression française. ANOCEF guidelines for the management of brain metastases Cancer Radiother. 2015 Feb;19(1):66-71. doi: 10.1016/j.canrad.2014.11.006. Epub 2015 Feb 7 Download PDF
  • Le Rhun E, Mateus C, Mortier L, Dhermain F, Guillot B, Grob JJ, Lebbe C, Thomas M, Jouary T, Leccia MT, Robert C, Systemic treatment of melanoma brain metastases Cancer Radiother. 2015 Feb;19(1):48-54 Download PDF
  • Le Rhun É, Taillibert S, Blonski M, Jouniaux Delbez N, Delgadillo D, Taillia H, Auquier P, Belin C, Bonnetain F, Varin D, Tallet A, Taillandier L, Supportive care, cognition and quality of life in brain metastases Cancer Radiother. 2015 Feb;19(1):55-60. doi: 10.1016/j.canrad.2014.11.003. Epub 2015 Jan 29 Download PDF
  • Lévy C, Allouache D, Lacroix J, Dugué AE, Supiot S, Campone M, Mahe M, Kichou S, Leheurteur M, Hanzen C, Dieras V, Kirova Y, Campana F, Le Rhun E, Gras L, Bachelot T, Sunyach MP, Hrab I, Geffrelot J, Gunzer K, Constans JM, Grellard JM, Clarisse B, Paoletti X, REBECA: a phase I study of bevacizumab and whole-brain radiation therapy for the treatment of brain metastasis from solid tumours Ann Oncol. 2015 Nov;26(11):2359. doi: 10.1093/annonc/mdv386 Download PDF
  • Ligier K, Maynou C, Leroy X, Robin YM, Martin P, Clisant S, Richard F, Penel N, Improvement of the initial management of sarcomas after the dissemination of evidence-based guidelines depends on the primary sarcoma location : a population-based study BMC Cancer. 2015 Apr 2;15:218. doi: 10.1186/s12885-015-1225- Download PDF
  • Metellus P, Bialecki E, Le Rhun E, Dhermain F, Neurosurgical and radiosurgical decision making in brain metastasis patients in the area of targeted therapies ? Chin Clin Oncol. 2015 Jun;4(2):19. doi: 10.3978/j.issn.2304-3865.2015.06.02 Download PDF
  • Métellus P, Tallet A, Dhermain F, Reyns N, Carpentier A, Spano JP, Azria D, Noël G, Barlési F, Taillibert S, Le Rhun É, Global brain metastases management strategy: a multidisciplinary-based approach Cancer Radiother. 2015 Feb;19(1):61-5. doi: 10.1016/j.canrad.2014.11.009. Epub 2015 Jan 31 Download PDF
  • Sakji-Dupré L, Le Rhun E, Templier C, Desmedt E, Blanchet B, Mortier L, Cerebrospinal fluid concentrations of vemurafenib in patients treated for brain metastatic BRAF-V600 mutated melanoma Melanoma Res. 2015 Aug;25(4):302-5. doi: 10.1097/CMR.0000000000000162 Download PDF
  • Taillibert S, Le Rhun E, Chamberlain MC, Tumor treating fields: a new standard treatment for glioblastoma ? Curr Opin Neurol. 2015 Dec;28(6):659-64. doi: 10.1097/WCO.0000000000000250 Download PDF
  • Taillibert S, Le Rhun É, Epidemiology of brain metastases Cancer Radiother. 2015 Feb;19(1):3-9. doi: 10.1016/j.canrad.2014.11.001. Epub 2015 Jan 27 Download PDF
  • Taillibert S, Taillandier L, Le Rhun E, Venous thrombosis in patients with high-grade glioma Curr Opin Oncol. 2015 Nov;27(6):516-21. doi: 10.1097/CCO.0000000000000226 Download PDF
  • Taillibert S, Conforti R, Bonneterre J, Bachelot T, Le Rhun E, Bernard-Marty C, Systemic treatment of brain metastases from breast cancer Cancer Radiother. 2015 Feb;19(1):36-42. doi: 10.1016/j.canrad.2014.12.003. Epub 2015 Feb 7 Download PDF
  • Taillandier L, Le Rhun É, Métellus P, Mornex F, Mazeron JJ, Editorial Cancer Radiother. 2015 Feb;19(1):1-2. doi: 10.1016/j.canrad.2014.11.005. Epub 2015 Feb 7 Download PDF
  • Tu Q, Wu X, Le Rhun E, Blonski M, Wittwer B, Taillandier L, De Carvalho Bittencourt M, Faure GC, CellSearch(®) technology applied to the detection and quantification of tumor cells in CSF of patients with lung cancer leptomeningeal metastasis Lung Cancer. 2015 Nov;90(2):352-7. doi: 10.1016/j.lungcan.2015.09.008. Epub 2015 Sep 14 Download PDF
  • Turpin A, Sharif A, Stoven L, Blond S, Maurage CA, Le Rhun E, The stem cell niche in glioblastoma: from fundamental aspects to targeted therapies Bull Cancer. 2015 Jan;102(1):24-33. doi: 10.1016/j.bulcan.2014.07.001. Epub 2015 Jan 6 Download PDF
  • Ursu R, Taillibert S, Banissi C, Vicaut E, Bailon O, Le Rhun E, Guillamo JS, Psimaras D, Tibi A, Sacko A, Marantidou A, Belin C, Carpentier AF, Immunotherapy with CpG-ODN in neoplastic meningitis: A phase I trial Cancer Sci. 2015 Sep;106(9):1212-8. doi: 10.1111/cas.12724. Epub 2015 Jul 29 Download PDF
  • Zairi F, Vieillard MH, Assaker R, Spine metastases: are minimally invasive surgical techniques living up to the hype ? CNS Oncol. 2015;4(4):257-64. doi: 10.2217/cns.15.15. Epub 2015 Jun 22 Download PDF
  • Zairi F, Le Rhun E, Bertrand N, Boulanger T, Taillibert S, Aboukais R, Assaker R, Chamberlain MC, Complications related to the use of an intraventricular access device for the treatment of leptomeningeal metastases from solid tumor: a single centre experience in 112 patients J Neurooncol. 2015 Sep;124(2):317-23. doi: 10.1007/s11060-015-1842-x. Epub 2015 Jun 13 Download PDF

Fundamentals

  • Arafah K, Longuespée R, Desmons A, Kerdraon O, Fournier I, Salzet M
    Lipidomics for Clinical Diagnosis: Dye Assisted Laser Desorption/Ionisation (DALDI) method for lipids detection in MALDI mass spectrometry imaging OMICS 2014, 18(8): 487-98 Download PDF
  • Cizkova D, Devaux S, Le Marrec-Croq F, Franck J, Slovinska L, Blasko J, Rosocha J, Spakova T, Lefebvre C, Fournier I, Salzet M.
    Modulation properties of factors released by bone marrow stromal cells on activated microglia: an in vitro study Sci Rep. 2014 Dec 19;4:7514. doi: 10.1038/srep07514 Download PDF
  • Cizkova D, Le Marrec-Croq F, Franck J, Slovinska L, Grulova I, Devaux S, Lefebvre C, Fournier I, Salzet M
    Alterations of protein composition along the rostro-caudal axis after spinal cord injury: proteomic, in vitro and in vivo analyses Front Cell Neurosci. 2014 Apr 17;8:105. doi: 10.3389/fncel.2014.00105. eCollection 2014 Download PDF Download Supplementary data
  • Diologent L, Franck J, Wisztorski M, Treizebre A, Focsa C, Fournier I, Ziskind M
    On the Origin of Increased Sensitivity and Mass Resolution Using Silicon Masks in MALDI Anal Chem. 2014 Feb 4;86(3):1404-13. doi: 10.1021/ac401329r. Epub 2014 Jan 22 Download PDF
  • Drago F, Sautière PE, Le Marrec-Croq F, Accorsi A, Van Camp C, Salzet M, Lefebvre C, Vizioli J
    Microglia of medicinal leech (Hirudo medicinalis) express a specific activation marker homologous to Vertebrate Ionized calcium-Binding Adapter molecule 1 (Iba1/alias Aif-1) Dev Neurobiol. 2014 Oct;74(10):987-1001. doi: 10.1002/dneu.22179. Epub 2014 Apr 22 Download PDF
  • Le Marrec-Croq F, Bocquet-Garçon A, Vizioli J, Van Camp C, Drago F, Franck J, Wisztorski M, Salzet M, Sautiere PE, Lefebvre C
    Calreticulin contributes to C1q-dependent recruitment of microglia in the leech Hirudo medicinalis Med Sci Monit. 2014 Apr 19;20:644-53. doi: 10.12659/MSM.890091 Download PDF
  • Longuespée R, Tastet C, Desmons A, Kerdraon O, Day R, Fournier I, Salzet M
    HFIP extraction followed by 2D CTAB-SDS PAGE separation: A new methodology for protein identification from tissue sections after MALDI mass spectrometry profiling for personalized medicine research OMICS. 2014 Jun;18(6):374-84. doi: 10.1089/omi.2013.0176. Epub 2014 May 19 Download PDF
  • Longuespée R, Couture, F, Levesque C, Kwiakowska, Desjardins R, Gagnon S, Vergara D, Maffia M, Fournier I, Salzet M, Day R
    Implications of proprotein convertases in ovarian cancer cell proliferation and tumor progression: insights for PACE4 as a therapeutic target Transl Oncol. 2014 May 9. pii: S1936-5233(14)00043-6. doi: 10.1016/j.tranon.2014.04.008 Download PDF
  • Longuespé R, Boyon C, Desmons A, Leblanc E, Farré I, Vinatier D, Day R, Fournier I, Salzet M
    Spectroimmunohistochemistry: a novel form of MALDI mass spectrometry imaging coupled to immunohistochemistry for tracking antibodies OMICS. 2014 Feb;18(2):132-41. doi: 10.1089/omi.2013.0075. Epub 2013 Dec 19 Download PDF
  • Mériaux C, Franck J, Park DB, Quanico J, Kim YH, Chung CK, Park YM, Steinbusch H, Salzet M, Fournier I
    Human temporal lobe epilepsy analyses by tissue proteomics Hippocampus. 2014 Jun;24(6):628-42. doi: 10.1002/hipo.22246. Epub 2014 Feb 28 Download PDF

Clinicals

  • Aboukais R, Zairi F, Reyns N, Le Rhun E, Touzet G, Blond S, Lejeune JP
    Surgery followed by radiosurgery: a deliberate valuable strategy in the treatment of intracranial meningioma Clin Neurol Neurosurg. 2014 Sep;124:123-6. doi: 10.1016/j.clineuro.2014.06.035. Epub 2014 Jul 6 Download PDF
  • Boyon C, Monsarrat N, Clouqueur E, Deruelle P
    Cervical ripening: is there an advantage for a double-balloon device in labor induction ? Gynecol Obstet Fertil. 2014 Oct;42(10):674-80. doi: 10.1016/j.gyobfe.2014.07.035. Epub 2014 Sep 22 Download PDF
  • Chamberlain M, Soffietti R, Raizer J, Rudà R, Brandsma D, Boogerd W, Taillibert S, Groves MD, Le Rhun E, Junck L, van den Bent M, Wen PY, Jaeckle KA
    Leptomeningeal metastasis: a Response Assessment in Neuro-Oncology critical review of endpoints and response criteria of published randomized clinical trials Neuro Oncol. 2014 Sep;16(9):1176-85. doi: 10.1093/neuonc/nou089. Epub 2014 May 27 Download PDF
  • Italiano A1, Le Cesne A, Mendiboure J, Blay JY, Piperno-Neumann S, Chevreau C, Delcambre C, Penel N, Terrier P, Ranchere-Vince D, Lae M, Le Guellec S, Michels JJ, Robin YM, Bellera C, Bonvalot S.
    Prognostic factors and impact of adjuvant treatments on local and metastatic relapse of soft-tissue sarcoma patients in the competing risks setting Cancer. 2014 Nov 1;120(21):3361-9. doi: 10.1002/cncr.28885. Epub 2014 Jul 10 Download PDF
  • Le Guellec S, Chibon F, Ouali M, Perot G, Decouvelaere AV, Robin YM, Larousserie F, Terrier P, Coindre JM, Neuville A
    Are peripheral purely undifferentiated pleomorphic sarcomas with MDM2 amplification dedifferentiated liposarcomas ? Am J Surg Pathol. 2014 Mar;38(3):293-304. doi: 10.1097/PAS.0000000000000131 Download PDF
  • Leblanc E, Vennin P, Narducci F, Merlot B, Bresson L, Farré I, Salzet M, Bertrand O, Maillez A, Adenis C, Prophylactic Adnexectomy in Women at Hereditary Risk for Ovarian Carcinomas: towards New Tracks ? Oncologie (2014) 16: 438-444 Download PDF
  • Mesdag V, Salzet M, Vinatier D.
    Trophoblast: Conductor of the maternal immune tolerance J Gynecol Obstet Biol Reprod (Paris). 2014 Nov;43(9):657-70. doi: 10.1016/j.jgyn.2014.06.008. Epub 2014 Jul 22 Download PDF
  • Taillibert S, Le Rhun E, Chamberlain MC, Intracranial cystic lesions: a review Curr Neurol Neurosci Rep. 2014 Sep;14(9):481. doi: 10.1007/s11910-014-0481-5 Download PDF
  • Toulmonde M1, Le Cesne A, Mendiboure J, Blay JY, Piperno-Neumann S, Chevreau C, Delcambre C, Penel N, Terrier P, Ranchère-Vince D, Lae M, Le Guellec S, Michels JJ, Robin YM, Bellera C, Italiano A, Long-term recurrence of soft tissue sarcomas: prognostic factors and implications for prolonged follow-up Cancer. 2014 Oct 1;120(19):3003-6. doi: 10.1002/cncr.28836. Epub 2014 Jun 18 Download PDF
  • Zairi F, Ouammou Y, Le Rhun E, Aboukais R, Blond S, Vermandel M, Deken V, Devos P, Reyns N, Relevance of gamma knife radiosurgery alone for the treatment of non-small cell lung cancer brain metastases Clin Neurol Neurosurg. 2014 Oct;125:87-93. doi: 10.1016/j.clineuro.2014.07.030. Epub 2014 Jul 27 Download PDF

  • Arafah K, Croix D, Vizioli J, Desmons A, Fournier I, Salzet M, Involvement of Nitric oxide through encannabinoids release in microglia activation during the course of CNS regeneration in the medicinal leech Glia. 2013 Apr;61(4):636-49. doi: 10.1002/glia.22462. Epub 2013 Jan 28 Download PDF
  • Bonnel D, Franck J, Mériaux C, Salzet M, Fournier I, Ionic matrices pre-spotted MALDI plates for patients markers following, drugs titration and MALDI MSI Anal Biochem. 2013 Mar 1;434(1):187-98. doi: 10.1016/j.ab.2012.10.035. Epub 2012 Nov 7 Download PDF
  • Franck J, Quanico J, Wisztorski M, Day R, Salzet M, Fournier I, Quantification Based Mass Spectrometry Imaging of Proteins by Parafilm Assisted Microdissection Anal Chem. 2013 Sep 3;85(17):8127-34. doi: 10.1021/ac4009397. Epub 2013 Aug 12 Download PDF
  • Gagnon H, Refaie S, Gagnon S, Desjardins R, Salzet M, Day R, Proprotein convertase 1/3 (PC1/3) in the rat alveolar macrophage cell line NR8383: localization,trafficking and effects on cytokine secretion PLoS One. 2013 Apr 24;8(4):e61557. doi: 10.1371/journal.pone.0061557. Print 2013 Download PDF
  • Hanssen S, Collinet P, Leblanc E, Salzet M, Vinatier D, Immunological analogies between ovarian cancer and pregnancy J Gynecol Obstet Biol Reprod (Paris). 2013 May;42(3):217-26. doi: 10.1016/j.jgyn.2012.10.007. Epub 2012 Nov 22 Download PDF
  • Le Marrec-Croq F, Drago F, Vizioli J, Sautière PE, Lefebvre C, The leech nervous system: A valuable model to study the microglia involvement in regenerative processes Clin Dev Immunol. 2013;2013:274019. doi: 10.1155/2013/274019. Epub 2013 Jun 26 Download PDF
  • Lonsguespée R, Boyon C, Kerdraon O, Ighodaro A, Desmons A, Vinatier D, Fournier I, Day R, Salzet M, Ovarian Cancer Patient Case Studies By Maldi Mass Spectrometry Profiling: A molecular study of endometrioid and serous carcinoma origins Proteomic Clinical Applications 2013,7(5-6): 337-54 Download PDF
  • Quanico J, Franck J, Dauly C, Strupat K, Dupuy J, Day R, Salzet M, Fournier I, Wisztorski M, Development of Liquid Microjunction Extraction Strategy for Improving Protein Identification from Tissue Sections J Proteomics. 2013 Feb 21;79:200-18. doi: 10.1016/j.jprot.2012.11.025. Epub 2013 Jan 2 Download PDF Download Supplementary data
  • Vanderperre B, Lucier JF, Tremblay G, Motard J, Vanderperre S, Wisztorski M, Salzet M, Boisvert FM, Roucou X, Direct detection of alternative open reading frames translation products in human significantly expands the proteome PLosOne 2013, 8(8):e70698 Download PDF
  • Vergara D, Simeonec P, Del Bocciod P, Totob C, Pieragostinod D, Tinellie A, Aciernoa R, Albertic S, Salzet M, Giannellig G, Sacchettad P, Maffia M, Comparative proteome profiling of breast tumor cell lines by gel electrophoresis and mass spectrometry reveals an epithelial mesenchymal transition associated protein signature Mol Biosyst. 2013 Jun;9(6):1127-38. doi: 10.1039/c2mb25401h Download PDF
  • Wisztorski M, Fatou B, Franck J, Desmons A, Farré I, Leblanc E, Fournier I, Salzet M, Microproteomics by Liquid Extraction Surface Analysis: Application to FFPE tissue to study the Fimbria region of tubo-ovarian cance Proteomics Clin Appl. 2013 Apr;7(3-4):234-40. doi: 10.1002/prca.201200070. Epub 2013 Mar 6 Download PDF

  • Boidin-Wichlacz C, Vergote D, Slomianny C, Jouy N, Salzet M, Tasiemski A, Morphological and functional characterization of leech circulating blood cells: role in immunity and neural repair Cell Mol Life Sci. 2012 May;69(10):1717-31. doi: 10.1007/s00018-011-0897-x. Epub 2011 Dec 11 Download PDF
  • Brignole-Baudouin F, Desbenoit N, Hamm G, Liang H, Both JP, Brunelle A, Fournier I, Guerineau V, Legouffe R, Stauber J, Touboul D, Wisztorski M, Salzet M, Laprevote O, Baudouin C, A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits PLoS One. 2012;7(11):e50180. doi: 10.1371/journal.pone.0050180. Epub 2012 Nov 27 Download PDF
  • Gagnon H, Franck J, Wisztorski M, Day R, Fournier I, Salzet M, Targeted mass spectrometry imaging: specific targeting mass spectrometry imaging technologies from history to perspective Prog Histochem Cytochem. 2012; 47(3): 133-74 Download PDF
  • Jung S, Sönnichsen FD, Hung CW, Tholey A, Boidin-Wichlacz C, Haeusgen W, Gelhaus C, Desel C, Podschun R, Waetzig V, Tasiemski A, Leippe M, Grötzinger J, Macin family of antimicrobial proteins combines antimicrobial and nerve repair activities J Biol Chem. 2012 Apr 20;287(17):14246-58. doi: 10.1074/jbc.M111.336495. Epub 2012 Mar 6 Download PDF
  • Longuespée R, Boyon C, Desmons A, Vinatier D, Leblanc E, Farré I, Wisztorski M, Ly K, D’Anjou F, Day R, Fournier I, Salzet M, Ovarian cancer molecular pathology Cancer Metastasis Rev. 2012 Dec;31(3-4):713-32. doi: 10.1007/s10555-012-9383-7 Download PDF
  • Longuespée R, Boyon C, Castellier C, Jacquet A, Desmons A, Kerdraon O, Vinatier D, Fournier I, Day R, Salzet M, The C-terminal fragment of the immunoproteasome PA28S (Reg alpha) as an early diagnosis and tumor-relapse biomarker: evidence from mass spectrometry profiling Histochem Cell Biol. 2012 Jul;138(1):141-54. doi: 10.1007/s00418-012-0953-0. Epub 2012 Apr 25 Download PDF
  • Ray-Coquard I, Chauvin F, Leblanc E, Caux C, Hoarau H, Bonnetain F, Christophe V, Sastre-Garau X, Lazennec G, Poulain L, Haie-Meder C, Pujade-Lauraine E, Salzet M, Deutsch E, Devouassoux M, Penault Llorca F, Lecuru F, Taieb S, Arveux P, Theillet C, Joly F, PAIR-gynaecology: multi/interdisciplinary for gynecologic cancer research. Problems needed to be resolved Bull Cancer. 2012 Apr 1;99(4):479-98. doi: 10.1684/bdc.2012.1558
  • Refaie S, Gagnon S, Gagnon H, Desjardins R, D’Anjou F, D’Orléans-Juste P, Zhu X, Steiner DF, Seidah NG, Lazure C, Salzet M, Day R, Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion J Biol Chem. 2012 Apr 27;287(18):14703-17. doi: 10.1074/jbc.M111.323220. Epub 2012 Mar 6 Download PDF
  • Tahtouh M, Garçon-Bocquet A, Croq F, Vizioli J, Sautière PE, Van Camp C, Salzet M, Nagnan-le Meillour P, Pestel J, Lefebvre C, Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis J Neuroinflammation. 2012 Feb 22;9:37. doi: 10.1186/1742-2094-9-37 Download PDF
  • Vergara D, Simeone P, Toraldo D, Del Boccio P, Vergaro V, Leporatti S, Pieragostino D, Tinelli A, De Domenico S, Alberti S, Urbani A, Salzet M, Santino A, Maffia M, Resveratrol downregulates Akt/GSK and ERK signalling pathways in OVCAR-3 ovarian cancer cells Mol Biosyst. 2012 Apr;8(4):1078-87. doi: 10.1039/c2mb05486h. Epub 2012 Jan 10 Download PDF

  • Bonnel D, Longuespee R, Franck J, Roudbaraki M, Gosset P, Day R, Salzet M, Fournier I, Multivariate analyses for biomarkers hunting and validation through on-tissue bottom-up or in-source decay in MALDI-MSI: application to prostate cancer Anal Bioanal Chem. 2011 Jul;401(1):149-65. doi: 10.1007/s00216-011-5020-5. Epub 2011 Apr 26 Download PDF
  • Bruand J, Alexandrov T, Sistla S, Wisztorski M, Meriaux C, Becker M, Salzet M, Fournier I, Macagno E, Bafna V, AMASS: algorithm for MSI analysis by semi-supervised segmentation J Proteome Res. 2011 Oct 7;10(10):4734-43. doi: 10.1021/pr2005378. Epub 2011 Aug 25 Download PDF
  • Bruand J, Sistla S, Mériaux C, Dorrestein PC, Gaasterland T, Ghassemian M, Wisztorski M, Fournier I, Salzet M, Macagno E, Bafna V, Automated querying and identification of novel peptides using MALDI mass spectrometric imaging J Proteome Res. 2011 Apr 1;10(4):1915-28. doi: 10.1021/pr101159e. Epub 2011 Mar 15 Download PDF
  • Cuvillier-Hot V, Boidin-Wichlacz C, Slomianny C, Salzet M, Tasiemski A, Characterization and immune function of two intracellular sensors, HmTLR1 and HmNLR, in the injured CNS of an invertebrate Dev Comp Immunol. 2011 Feb;35(2):214-26. doi: 10.1016/j.dci.2010.09.011. Epub 2010 Oct 29 Download PDF
  • D’Anjou F, Routhier S, Perreault JP, Latil A, Bonnel D, Fournier I, Salzet M, Day R, Molecular Validation of PACE4 as a Target in Prostate Cancer Transl Oncol. 2011 Jun;4(3):157-72. Epub 2011 Jun 1 Download PDF
  • Grimaldi A, Banfi S, Vizioli J, Tettamanti G, Noonan DM, de Eguileor M, Cytokine loaded biopolymers as a novel strategy to study stem cells during wound-healing processes Macromol Biosci. 2011 Aug 11;11(8):1008-19. doi: 10.1002/mabi.201000452. Epub 2011 Mar 11 Download PDF
  • Meriaux C, Arafah K, Tasiemski A, Wisztorski M, Bruand J, Boidin-Wichlacz C, Desmons A, Debois D, Laprévote O, Brunelle A, Gaasterland T, Macagno E, Fournier I, Salzet M, Multiple changes in peptide and lipid expression associated with regeneration in the nervous system of the medicinal leech PLoS One. 2011 Apr 22;6(4):e18359. doi: 10.1371/journal.pone.0018359 Download PDF
  • Van Dyck S, Caulier G, Todesco M, Gerbaux P, Fournier I, Wisztorski M, Flammang P, The triterpene glycosides of Holothuria forskali: usefulness and efficiency as a chemical defense mechanism against predatory fish J Exp Biol. 2011 Apr 15;214(Pt 8):1347-56. doi: 10.1242/jeb.050930 Download PDF
  • Vidal-Dupiol J, Ladrière O, Destoumieux-Garzón D, Sautière PE, Meistertzheim AL, Tambutté E, Tambutté S, Duval D, Fouré L, Adjeroud M, Mitta G, Innate immune responses of a scleractinian coral to vibriosis J Biol Chem. 2011 Jun 24;286(25):22688-98. doi: 10.1074/jbc.M110.216358. Epub 2011 May 2 Download PDF

  • Croq F, Vizioli J, Tuzova M, Tahtouh M, Sautiere PE, Van Camp C, Salzet M, Cruikshank WW, Pestel J, Lefebvre C, A homologous form of human interleukin 16 is implicated in microglia recruitment following nervous system injury in leech Hirudo medicinalis Glia. 2010 Nov 1;58(14):1649-62. doi: 10.1002/glia.21036 Download PDF
  • van Dyck S, Flammang P, Meriaux C, Bonnel D, Salzet M, Fournier I, Wisztorski M, Localization of secondary metabolites in marine invertebrates: contribution of MALDI MSI for the study of saponins in Cuvierian tubules of H. forskali PLoS One. 2010 Nov 10;5(11):e13923. doi: 10.1371/journal.pone.0013923 Download PDF
  • El Ayed M, Bonnel D, Longuespée R, Castelier C, Franck J, Vergara D, Desmons A, Tasiemski A, Kenani A, Vinatier D, Day R, Fournier I, Salzet M, MALDI imaging mass spectrometry in ovarian cancer for tracking, identifying, and validating biomarkers Med Sci Monit. 2010 Aug;16(8):BR233-45 Download PDF
  • Franck J, Longuespée R, Wisztorski M, Van Remoortere A, Van Zeijl R, Deelder A, Salzet M, McDonnell L, Fournier I, MALDI mass spectrometry imaging of proteins exceeding 30,000 daltons Med Sci Monit. 2010 Sep;16(9):BR293-9 Download PDF
  • Franck J, Ayed ME, Wisztorski M, Salzet M, Fournier I, On tissue protein identification improvement by N-terminal peptide derivatization Methods Mol Biol. 2010;656:323-38. doi: 10.1007/978-1-60761-746-4_19 Download PDF
  • Macagno ER, Gaasterland T, Edsall L, Bafna V, Soares MB, Scheetz T, Casavant T, Da Silva C, Wincker P, Tasiemski A, Salzet M, Construction of a medicinal leech transcriptome database and its application to the identification of leech homologs of neural and innate immune genes BMC Genomics. 2010 Jun 25;11:407. doi: 10.1186/1471-2164-11-407 Download PDF
  • Meriaux C, Franck J, Wisztorski M, Salzet M, Fournier I, Liquid ionic matrixes for MALDI mass spectrometry imaging of lipids J Proteomics. 2010 Apr 18;73(6):1204-18. doi: 10.1016/j.jprot.2010.02.010. Epub 2010 Feb 24 Download PDF Download Supplementray Data
  • van Remoortere A, van Zeijl RJ, van den Oever N, Franck J, Longuespée R, Wisztorski M, Salzet M, Deelder AM, Fournier I, McDonnell LA, MALDI imaging and profiling MS of higher mass proteins from tissue J Am Soc Mass Spectrom. 2010 Nov;21(11):1922-9. doi: 10.1016/j.jasms.2010.07.011. Epub 2010 Aug 4 Download PDF
  • Sethi J, Zhao B, Cuvillier-Hot V, Boidin-Wichlacz C, Salzet M, Macagno ER, Baker MW, The receptor protein tyrosine phosphatase HmLAR1 is up-regulated in the CNS of the adult medicinal leech following injury and is required for neuronal sprouting and regeneration Mol Cell Neurosci. 2010 Dec;45(4):430-8. doi: 10.1016/j.mcn.2010.08.002. Epub 2010 Aug 12 Download PDF
  • Stauber J, Ayed ME, Wisztorski M, Salzet M, Fournier I, Specific MALDI-MSI: Tag-Mass Methods Mol Biol. 2010;656:339-61. doi: 10.1007/978-1-60761-746-4_20 Download PDF
  • Stauber J, MacAleese L, Franck J, Claude E, Snel M, Kaletas BK, Wiel IM, Wisztorski M, Fournier I, Heeren RM, On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry J Am Soc Mass Spectrom. 2010 Mar;21(3):338-47. doi: 10.1016/j.jasms.2009.09.016. Epub 2009 Sep 29 Download PDF
  • Tasiemski A, Salzet M, Leech immunity: from brain to peripheral responses Adv Exp Med Biol. 2010;708:80-104 Download PDF
  • Vergara D, Merlot B, Lucot JP, Collinet P, Vinatier D, Fournier I, Salzet M, Epithelial-mesenchymal transition in ovarian cancer Cancer Lett. 2010 May 1;291(1):59-66. doi: 10.1016/j.canlet.2009.09.017. Epub 2009 Oct 31 Download PDF
  • Wisztorski M, Franck J, Salzet M, Fournier I, MALDI direct analysis and imaging of frozen versus FFPE tissues: what strategy for which sample ? Methods Mol Biol. 2010;656:303-22. doi: 10.1007/978-1-60761-746-4_18 Download PDF

  • Abbas A, Dargent T, Croix D, Salzet M, Bocquet B, Ex-vivo detection of neural events using THz BioMEMS Med Sci Monit. 2009 Sep;15(9):MT121-5 Download PDF
  • Djidja MC, Francese S, Loadman PM, Sutton CW, Scriven P, Claude E, Snel MF, Franck J, Salzet M, Clench MR, Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections Proteomics. 2009 May;9(10):2750-63. doi: 10.1002/pmic.200800624 Download PDF
  • Franck J, Arafah K, Elayed M, Bonnel D, Vergara D, Jacquet A, Vinatier D, Wisztorski M, Day R, Fournier I, Salzet M, MALDI imaging mass spectrometry: state of the art technology in clinical proteomics Mol Cell Proteomics. 2009 Sep;8(9):2023-33. doi: 10.1074/mcp.R800016-MCP200. Epub 2009 May 18 Download PDF
  • Franck J, Arafah K, Barnes A, Wisztorski M, Salzet M, Fournier I, Improving tissue preparation for matrix-assisted laser desorption ionization mass spectrometry imaging. Part 1: using microspotting Anal Chem. 2009 Oct 1;81(19):8193-202. doi: 10.1021/ac901328p Download PDF Download Supplementary Data
  • Franck J, El Ayed M, Wisztorski M, Salzet M, Fournier I, On-tissue N-terminal peptide derivatizations for enhancing protein identification in MALDI mass spectrometric imaging strategies Anal Chem. 2009 Oct 15;81(20):8305-17. doi: 10.1021/ac901043n Download PDF Download Supplementary Data
  • Galinier R Roger E, Sautiere PE, Aumelas A, Banaigs B, Mitta G, Halocyntin and papillosin, two new antimicrobial peptides isolated from hemocytes of the solitary tunicate, Halocynthia papillosa J Pept Sci. 2009 Jan;15(1):48-55. doi: 10.1002/psc.1101 Download PDF
  • Stauber J, El Ayed M, Wisztorski M, Day R, Fournier I, Salzet M, Polymerase chain reaction and immunoassay—matrix assisted laser desorption mass spectrometry using tag-mass technology: new tools to break down quantification limits and multiplexes Anal Chem. 2009 Nov 15;81(22):9512-21. doi: 10.1021/ac901416s Download PDF
  • Schikorski D, Cuvillier-Hot V, Boidin-Wichlacz C, Slomianny C, Salzet M, Tasiemski A, Deciphering the immune function and regulation by a TLR of the cytokine EMAPII in the lesioned central nervous system using a leech model J Immunol. 2009 Dec 1;183(11):7119-28. doi: 10.4049/jimmunol.0900538. Epub 2009 Nov 16 Download PDF
  • Tahtouh M, Croq F, Vizioli J, Sautiere PE, Van Camp C, Salzet M, Daha MR, Pestel J, Lefebvre C, Evidence for a novel chemotactic C1q domain-containing factor in the leech nerve cord Mol Immunol. 2009 Feb;46(4):523-31. doi: 10.1016/j.molimm.2008.07.026. Epub 2008 Oct 25 Download PDF
  • Tahtouh M, Croq F, Lefebvre C, Pestel J, Is complement good, bad, or both? New functions of the complement factors associated with inflammation mechanisms in the central nervous system Eur Cytokine Netw. 2009 Sep;20(3):95-100. doi: 10.1684/ecn.2009.0157 Download PDF

  • Fournier I, Franck J, Wisztorski M, Macagno E, Salzet M, MALDI imaging: a Review of the Current Status of the Technology Neurosci. Imaging (2008) 3(1), 19-32
  • Jardin-Mathé O, Bonnel D, Franck J, Wisztorski M, Macagno E, Fournier E, Salzet M, MITICS: Applications to Biomarkers found in FFPE Tissues from 6-OHDA treated Rats Journal of Proteomics (2008), 71(3), 332-345 Download PDF
  • Lefebvre C, Vandenbulcke F, Bocquet B, Tasiemski A, Desmons A, Verstraete M, Salzet M, Cocquerelle C, Cathepsin L and cystatin B gene expression discriminates immune coelomic cells in the leech Theromyzon tessulatum Dev Comp Immunol. (2008) 32(7): 95-807 Download PDF
  • Salome N, Tasiemski A, Dutriez I, Wigger A, Landgraf R, Viltart O, Immune challenge induces differential corticosterone and interleukin-6 responsiveness in rats bred for extremes in anxiety-related behavio Neuroscience. (2008),151(4): 1112-8 Download PDF
  • Schikorski D, Cuvillier-Hot V, Leippe M, Boidin-Wichlacz C, Slomianny C, Macagno E, Salzet M, Tasiemski A, Microbial challenge promotes the regenerative process of the injured central nervous system of the medicinal leech by inducing the synthesis of antimicrobial peptides in neurons and microglia J Immunol. (2008) 181(2): 1083-95 Download PDF
  • Stauber J, Lemaire R, Franck J, Bonnel D, Croix D, Day R, Wisztorski M, Salzet M, Fournier I, MALDI Imaging of FFPE Tissues: Application to Model Animals of Parkinson Disease for Biomarker Hunting Prot Res J.. (2008) 7(3), 969-978 Download PDF
  • Wisztorski M, Croix D, Macagno E, Fournier I, Salzet M, Molecular MALDI Imaging: An Emerging Technology for Neuroscience Studies Dev. Neurobiol. (2008) 68(6), 845-858 Download PDF
  • Wisztorski M, Salzet M, Fournier I, Tissue Imaging Using MALDI Mass Spectrometry: The New Frontier of Histopathology Proteomics Expert Review Proteomics (2008) 5(3), 413-24 Download PDF

  • Dreisewerd K, Lemaire R, Pohlentz G, Wisztorski M, Berkenkamp S, Hillenkamp F, Salzet M, Fournier I, Molecular profiling of Matrix-coated and native tissue sections by UV- and IR-MALDI-O-TOF-MS Anal. Chem. (2007) 79(6), 2463-2471 Download PDF
  • Lemaire R, Desmons A, Tabet JC, Day R, Salzet M, Fournier I, Direct Analysis and MALDI Imaging of Formalin Fixed, Paraffin Embedded Tissue Sections J. Prot. Res. (2007) 6, 1295-1305 Download PDF
  • Lemaire R, Stauber J, Wisztorski M, Van Camp C, Desmons A, Deschamps M, Proess G, Rudlof I, Woods AS, Day R, Salzet M, Fournier I, TAG-MASS: Specific Molecular Imaging of Transcriptome and Proteome by Mass Spectrometry Based on Photocleavable Tag J. Prot. Res. (2007) 6, 2057-2067 Download PDF Download Supplementary Data
  • Lemaire R, Aït Menguellet S, Stauber J, Marchaudon V, Lucot JP, Collinet P, Farine MO, Vinatier D, Day R, Ducoroy P, Salzet M, Fournier I, Specific MALDI Imaging and Profiling for Biomarker Hunting and Validation: Fragment of the 11S Proteasome Activator Complex, Reg Alpha Fragment, Is a New Potential Ovary Cancer Biomarker J. Prot Res. (2007) 6 (11), 4127-4134 Download PDF
  • Tasiemski A, Schikorski D, Le Marrec-Croq F, Pontoire-Van Camp C, Boidin-Wichlacz C, Sautière PE, Hedistin: A novel antimicrobial peptide containing bromotryptophan constitutively expressed in the NK cells-like of the marine annelid, Nereis diversicolor Dev Comp Immunol. (2007) 31(8): 749-62 Download PDF
  • Toillon RA, Lagadec C, Page A, Chopin V, Sautière PE, Ricort JM, Lemoine J, Zhang M, Hondermarck H, Le Bourhis X, Proteomics demonstration that normal breast epithelial cells can induce apoptosis of breast cancer cells through insulin-like growth factor-binding protein-3 and maspin Mol Cell Proteomics. (2007) 6(7): 1239-47 Download PDF
  • Wisztorski M, Lemaire R, Stauber J, Aït-Menguellet S, Jardin-Mathé O, Day R, Salzet M, Fournier I, Imagerie MALDI: Une Nouvelle Technologie pour Découvrira et Valider de Nouveaux Biomarqueurs Médecine Sciences. (2007) 23(hors série N°1), 31-36 Download PDF
  • Wisztorski M, Lemaire R, Stauber J, Aït Menguellet S, Croix D, Jardin Mathé O, Day R, Salzet M, Fournier I, New developments in MALDI Imaging for Pathology Proteomics Studies Curr. Pharm. Design (2007) 13(32), 3317-3324 Download PDF

  • Bouchut A, Sautiere PE, Coustau C, Mitta G, Compatibility in the Biomphalaria glabrata/Echinostoma caproni model: Potential involvement of proteins from hemocytes revealed by a proteomic approach Acta Trop. (2006) 98(3):234-46 Download PDF
  • Lansac G, Dong W, Dubois CM, Ben Larbi N, Afonso C, Fournier I, Salzet M, Day R, Lipopolysaccharide Mediated Regulation of Neuroendocrine Associated Proprotein Convertases and NeuropeptidePrecursor Processing in the Rat Spleen J .Neuroimmunol. (2006) 171(1-2), 57-71 Download PDF
  • Lemaire R, Tabet JC, Ducoroy P, Hendra JB, Salzet M, Fournier I, Solid Ionic Matrices for Direct Tissue Analysis and MALDI Imaging Anal. Chem. (2006) 78, 809-819 Download PDF
  • Lemaire R, Wisztorski M, Desmons A, Tabet JC, Day R, Salzet M, Fournier I, MALDI-MS Direct Tissue Analysis of Proteins: Improving Signal Sensitivity Using Organic Treatments Anal. Chem. (2006) 78, 7145-7153 Download PDF
  • Salzet M, Tasiemski A, Cooper E, Innate immunity in lophotrochozoans: the annelids Curr Pharm Des. (2006) 12(24): 3043-50 Download PDF
  • Stauber J, Lemaire R, Wisztorski M, Aït-Menguellet S,Lucot JP, Vinatier D, Desmons A, Deschamps M, Proess G, Rudlof I, Salzet M, Fournier I, New Developments in MALDI Imaging Mass Spectrometry for Pathological Proteomics Studies, Introduction to a Novel Concept, the Specific MALDI Imaging Mol. Cell. Proteomics (2006) 5(10), S247-S247
  • Vergote D, Macagno ER, Salzet M, Sautière PE, Proteome modifications of the medicinal leech nervous system under bacterial challenge Proteomics. (2006) 6(17): 4817-25 Download PDF

  • Brogden KA, Guthmiller JM, Salzet M, Zasloff M, The nervous system and innate immunity: the neuropeptide connection Nat Immunol. (2005) 6(6): 558-64
  • Clynen E, Schoofs L, Salzet M, Trypsin and Chymotrypsin Inhibitors in Insects and Gut Leeches: an update Medical Chemistry Reviews (2005) 3: 197-206
  • Lemaire R, Lucot JP, Collinet P, Vinatier D, Tabet JC, Salzet M, Fournier I, New Developments in Direct Analysis by MALDI Mass Spectrometry for the Study of Ovarian Cancer Mol. Cel.. Proteomics (2005) 4(8), S306-S306
  • Levoye A, Mouillac B, Rivière G, Vieau D, Salzet M, Breton C, Cloning, expression and pharmacological characterization of a vasopressin-related receptor in an annelid, the leech Theromyzon tessulatum J Endocrinol. (2005) 184(1): 277-89 Download PDF
  • Salzet M, Neuropeptide-derived antimicrobial peptides from invertebrates for biomedical applications Curr Med Chem. (2005) 12(26): 3055-61 Download PDF
  • Vergote D, Bouchut A, Sautière PE, Roger E, Galinier R, Rognon A, Coustau C, Salzet M, Mitta G, Characterisation of proteins differentially present in the plasma of Biomphalaria glabrata susceptible or resistant to Echinostoma caproni Int J Parasitol. (2005) 35(2): 215-24 Download PDF

  • d’Anjou F, Bergeron LJ, Ben Larbi N, Fournier I, Salzet M, Perreault JP, Day R, Silencing of SPC2 Expression using an Engineered Delta Ribozyme in the Mouse Beta TC-3 Endocrine Cell Line J Biol Chem. (2004) 279(14),14232-14239 Download PDF
  • Deloffre L, Sautiere PE, Huybrechts R, Hens K, Vieau D, Salzet M, Angiotensin-converting enzyme inhibition studies by natural leech inhibitors by capillary electrophoresis and competition assay Eur J Biochem. (2004) 271(11): 2101-6 Download PDF
  • Giménez-Bonafé P, Soler FM, Buesa C, Sautière PE, Ausió J, Kouach M, Kasinsky HE, Chiva M, Chromatin organization during spermiogenesis in Octopus vulgaris. II: DNA-interacting proteins Mol Reprod Dev. (2004) 68(2): 232-9 Download PDF
  • Lefebvre C, Cocquerelle C, Vandenbulcke F, Hot D, Huot L, Lemoine Y, Salzet M, Transcriptomic analysis in the leech Theromyzon tessulatum: involvement of cystatin B in innate immunity Biochem J. (2004) 380(Pt 3): 617-25 Download PDF
  • Rivière G, Michaud A, Deloffre L, Vandenbulcke F, Levoye A, Breton C, Corvol P, Salzet M, Vieau D, Characterization of the first non-insect invertebrate functional angiotensin-converting enzyme (ACE): leech TtACE resembles the N-domain of mammalian ACE Biochem J. (2004) 382(Pt 2): 565-73 Download PDF
  • Stefano GB, Salamon E, Magazine HI, Salzet M, Knauf C, Prevot V, Cyclic nitric oxide release by human, rat and invertebrate tissues: examples of physiological implications in Biomedical Significance of Nitric Oxide Med. Sci. Monitor
  • Tasiemski A, Vandenbulcke F, Mitta G, Lemoine J, Lefebvre C, Sautière PE, Salzet M, Molecular characterization of two novel antibacterial peptides inducible upon bacterial challenge in an annelid, the leech Theromyzon tessulatum J Biol Chem.( 2004) 279(30): 30973-82 Download PDF
  • Vergote D, Sautière PE, Vandenbulcke F, Vieau D, Mitta G, Macagno ER, Salzet M, Up-regulation of neurohemerythrin expression in the central nervous system of the medicinal leech, Hirudo medicinalis, following septic injury J Biol Chem. (2004) 279(42): 43828-37 Download PDF

  • Deloffre L, Salzet B, Vieau D, Andries JC, Salzet M, Antibacterial properties of hemerythrin of the sand worm Nereis diversicolor Neuro Endocrinol Lett. (2003) 24(1-2): 39-45 Download PDF
  • Fournier I, Day R, Salzet M, Direct analysis of neuropeptides by in situ MALDI-TOF mass spectrometry in the rat brain Neuroendocrinol. Lett (2003) 24, 9-14 Download PDF
  • Lefebvre C, Salzet M, Annelid neuroimmune system Curr Pharm Des. 2003; 9(2): 149-58 Download PDF
  • Salzet M, Stefano G, Chromacin-like peptide in leeches Neuro Endocrinol Lett. (2003) 24(3-4): 227-32 Download PDF
  • Salzet M, Day R, Endocrine markers of cellular immunity: defining the endocrine phenotype J Soc Biol. (2003) 197(2): 97-101
  • Salzet M, Day R, Endocrine markers of cellular immunity: defining the endocrine phenotype J.Soc Biol. (2003)197(2): 97-101
  • Sergeant N, Wattez A, Galván-valencia M, Ghestem A, David JP, Lemoine J, Sautiére PE, Dachary J, Mazat JP, Michalski JC, Velours J, Mena-López R, Delacourte A, Association of ATP synthase alpha-chain with neurofibrillary degeneration in Alzheimer’s disease Neuroscience. (2003) 117(2):293-303 Download PDF
  • Srour N, Lebel A, McMahon S, Fournier I, Fugere M, Day R, Dubois CM, TACE/ADAM-17 Maturation and Activation of Sheddase Activity Require Proprotein Convertase Activity FEBS Lett. (2003) 554, 275-283 Download PDF

  • Day R, Salzet M, The neuroendocrine phenotype, cellular plasticity, and the search for genetic switches: redefining the diffuse neuroendocrine system Neuro Endocrinol Lett. (2002) 23(5-6): 447-51 Download PDF
  • Gimenez-Bonafé P, Ribes E, Sautière P, Gonzalez A, Kasinsky H, Kouach M, Sautière PE, Ausió J, Chiva M, Chromatin condensation, cysteine-rich protamine, and establishment of disulphide interprotamine bonds during spermiogenesis of Eledone cirrhosa (Cephalopoda) Eur J Cell Biol. (2002) 81(6): 341-9 Download PDF
  • Matias I, Pochard P, Orlando P, Salzet M, Pestel J, Di Marzo V, Presence and regulation of the endocannabinoid system in human dendritic cells Eur J Biochem. (2002) 269(15): 3771-8 Download PDF
  • Salzet M, Stefano GB, Cannabinoid system in invertebrates Prostaglandins, Leukotrienes & Essential Fatty Acids (2002) 66: 353-361
  • Salzet M, Verger-Bocquet M, Cellular localization of a chromogranin B-like derived peptides in leeches Neuro Endocrinol Lett. (2002) 23(3): 209-12 Download PDF
  • Salzet M, Antimicrobial peptides are signaling molecules Trends Immunol. (2002) 23(6): 283-4 Download PDF
  • Salzet M, Stefano GB, The endocannabinoid system in invertebrates Prostaglandins Leukot Essent Fatty Acids. (2002) 66(2-3): 353-61 Download PDF
  • Salzet M, Neuroimmunology of Opioids : from Invertebrates to human Neuroendocrinol Lett. (2002) 22: 451-457
  • Salzet M, Immune cells express endocrine markers Neuroendocrinol. Lett. (2002) 23: 8-9
  • Salzet M, Immune modulation by non-classical opioid families throughout animal Placebo (2002) 3(1): 12-25 kingdom
  • Salzet M, Leech thrombin inhibitors Curr Pharm Des. (2002) 8(7): 493-503 Download PDF
  • Salzet M, Immune cells express endocrine markers Neuro Endocrinol Lett. (2002) 23(1): 8-9 Download PDF
  • Schoofs L, Clynen E, Salzet M, Trypsin and chymotrypsin inhibitors in insects and gut leeches Curr Pharm Des. (2002) 8(7): 483-91 Download PDF
  • Stefano GB, Salzet M, Magazine HI, Cyclic nitric oxide release by human granulocytes, and invertebrate ganglia and immunocytes: nano-technological enhancement of amperometric nitric oxide determination Med Sci Monit. (2002) 8(6): BR199-204 Download PDF
  • Stefano GB, Magazine HI, Salzet M, Cyclic nitric oxide release by human granulocytes, and invertebrate gangliaand immunocytes: nano-technological enhancement of amperometric nitric oxide determination Med Sci Monit (2002) 8(6): 199-204
  • Tasiemski A, Hammad H, Vandenbulcke F, Breton C, Bilfinger TJ, Pestel J, Salzet M, Presence of chromogranin-derived antimicrobial peptides in plasma during coronary artery bypass surgery and evidence of an immune origin of these peptides Blood. (2002) 100(2): 553-9 Download PDF
  • Vizioli J, Salzet M, Antimicrobial peptides versus parasitic infections ? Trends Parasitol. (2002) 18(11): 475-6 Download PDF
  • Vizioli J, Salzet M, Antimicrobial peptides from animals: focus on invertebrates Trends Pharmacol Sci. (2002) 23(11): 494-6 Download PDF