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Pr. Isabelle Fournier

Professor at University Lille 1
IUF Member

Photo YsaUniversity Lille 1
Bât SN3, 1er étage, porte 113

Tel : +33 (0)3 20 43 41 94
Fax : +33 (0)3 20 43 40 54

Email : isabelle.fournier@univ-lille1.fr

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ORCID ID
orcid.org/0000-0003-1096-5044

DIPLOMA
1995-1996
M2 Spectroscopy & Organic Physicochemistry
University Paris 6, Laboratoire de Chimie Structurale Organique & Biologique, CNRS-UMR 7613, Paris, France
1996-2000
PhD, Speciality Spectroscopy & Organic Physicochemistry, University Paris 6, Laboratoire Chimie Structurale Organique & Biologique, CNRS-UMR 7613, Paris, France
2005
Habilitation, Laboratoire de Neuroimmunologie des Annélides, FRE-CNRS 2933, University Lille 1, Lille, France

PROFESSIONAL EXPERIENCE
2000-2001
Posdoctorate (05/2000-08/2001), Laboratoire "Instrumentelle Analytische Chemie", Pr. M.Karas, University J. W. Goethe de Frankfurt, Germany
2001-2002Posdoctorate (09/2001-09/2002), Laboratoire de Neuroimmunologie des Annélides, CNRS-UMR 8017, University Lille1, France
2002-2003
Assistant Professor (10/2002-01/2003), Laboratoire de Neuroimmunologie des Annélides, CNRS-UMR 8017, University Lille 1, France
2003-2009Associate Professor, Laboratoire de Neuroimmunologie des Annélides, CNRS-UMR 8017, University Lille 1, France
2009-2011
Professor
2011-
1st grade Professor

PRICES & DISTINCTIONS
2009
Junior Member Institut Universitaire de France
2009-
Excellent Scientific Prime
2011
Great Price Special of Science, Agriculture and Art Societyof Lille

RESPONSABILITIES
2004-
Group Leader MALDI Imaging Team at Laboratoire de Spectrométrie de Masse Biologique Fondamentale & Appliquée, Université Lille 1. Starting Grant 2004 for team creation, AERES Notation A
2007-2008
Member of Scientific Council University Lille 1
2007-2009
Nominated member CNU (National Committee University) section N°68
2009-2011
Nominated member Parity Technique Committee (CTP) University Lille 1
2010-
Assistant Director of Laboratoire de Spectrométrie de Masse Biologique Fondamentale et Appliquée
2011
Assistant Director of Federative Research Institute IFR 147
2012
Member of Scientific Council University Lille 1
2012
Responsible Imaging Platform & management committee member, SIRIC ONCOLILLE, National Institute of Cancer, Integrated Research in Cancer Site (SIRIC)

TEATCHING RESPONSABILITES
2003-2009
Responsible Teaching Unit in the Professional Master of Proteomics
2005-2009
Responsible Teaching Unit in the Research Master in Life Physico-chemistry
2005-2009
Responsible Teaching Unit in the IUP Genomic and Proteomic, M1, S2
2009-
Responsible Teaching Unit in the International Master Advanced Spectroscopy in Chemistry, M1, S2, Spectroscopy for life sciences
2010-
Responsible Teaching Unit, Master Biology & Biotechnology, Specialty Genomic & Proteomic, Proteomics, M2, S3, Mass Spectrometry & M2, S4, Training sessions
2010-
Responsible Teaching Unit, Master Biology & Biotechnology, Specialty Genomic & Proteomic, M1, S2, Proteome Analysis
2010-
Responsible Teaching Unit, Master Biology & Biotechnology, Specialty Health Biology, M1, S2, Proteins Structural Analysis

SICENTIFIC AKNOWLEDGMENT & EXPERTISES

  1. Reviewer for international journals
  2. Expertise
    - France: Région Centre, ANRT, Région Ile de France, Canceropôle Ile de France, AERES
    - International: Belgium (ARC Wallonie, FNRS), UK (Cancer Research, BBSRC, MSS), Netherlands (Genomic Initiative), Germany (DFG), Loand (Polish Science Foundation), Canada (FRNTQ)
  3. Management Committee Member of COST Action BM1104, FP7 (2011-2016)
  4. Editorial of International Journals
    - Associated editor for Journal of Clinical Bioinformatics et Journal of Integrated Omics
  5. Treasurer of the French Society for Mass Spectrometry (09/2007-09/2008)
  6. Conferences organization
    - Scientific committee 25èmes Journées de la Société Française de Spectrométrie de Masse, Grenoble, 8-11 September (2008) ; Scientific Committee SMAP (Mass Spectrometry and Proteomic Analysis) 2009, Dijon, 14-17 September (2009)
  7. Conference Chair
    - Annual Conference French Society for Electrophoresis and Proteomics Analysis (SFEAP) , Saint-Malo, 16-18 October, 2006 ; Conference Mass Spectrometry and Proteomic Analysis SMAP), Dijon, 14-17 September, 2009 ; Desorption 2010 Conference Seillac, 30 Mai- 3 June, 2010 ; Conference Mass Spectrometry and Proteomic Analysis SMAP) Avignon, 19-22 September 2011

VALORISATION

  1. 9 international patents, 2 delivered in EU & US
  2. Co-funding IMABIOTECH Start-Up

SCIENTIFIC PROJECTS

  1. Coordinator
    - Research Medical Foundation, FRM (2002), National Starting Grant ACI « Jeunes Chercheurs et jeunes Chercheuses » (2004), National Institute for Cancer (2006), National Grants ANR-Program PCV, BIOSPIM (2008), ANR-Program Blanc, FUN MALDI (2009), ARCIR/FEDER Région Nord-Pas de Calais (2010)
  2. Project Partner
    - ANR-Program PIRIBIO- MASDA EYE (2010), ISAO Internationale Stichting Alzheimer Onderzoek (2010), KORANET International Cooperation Program with Korea (2010) FP7, Action COST, Mass Spectrometry Imaging: New Tools for Health Care Research (2011)

RESEARCH THEMATICS
1995-2001
Fundamental of MALDI desorption/ionization processes
2001-
MALDI Mass Spectrometry Imaging: Developments and Application

ONGOING PROJECTS

  1. Developments
    - IDENTITI: MALDI MS Imaging developments of strategies for protein identification
    - TDXMS: Development of a new strategy for studying proteins conformation at tissue level
    - SPIDER-MASS: Development of a system for in vivo Imaging by MS
  2. Applications
    - Physiopathological mechanisms of ovarian cancer
    - Leech regeneration vs. spinal cord injury of vertebrates

PUBLICATIONS

  1. 64 publications in international peer-reviewed journals, 9 patents, 8 books chapters on invitation, 71 oral communications among which 51 on invitation
  1. [1] R. Lemaire, J.C. Tabet, P. Ducoroy, J.B. Hendra, M.Salzet, I. Fournier, Anal. Chem. (2006) 78, 809-819, Solid Ionic Matrices for Direct Tissue Analysis and MALDI Imaging
  2. [2] R. Lemaire, A. Desmons, J.C. Tabet R. Day, M. Salzet, I. Fournier, J. Prot. Res. (2007), 6, 1295-1305,Direct Analysis and MALDI Imaging of Formalin Fixed, Paraffin Embedded Tissue Sections
  3. [3] R. Lemaire, J. Stauber, M. Wisztorski, C. Van Camp, A. Desmons, M. Deschamps, G. Proess, I. Rudlof, A. S. Woods, R. Day, M. Salzet, I. Fournier, J. Prot. Res. (2007), 6, 2057-2067, TAG-MASS: Specific Molecular Imaging of Transcriptome and Proteome by Mass Spectrometry Based on Photocleavable Tag
  4. [4] R. Lemaire, S. Aït-Menguellet, J. Stauber, V. Marchaudon, J-P. Lucot, P. Collinet, M-O. Farine, D. Vinatier, R. Day, P. Ducoroy, M. Salzet, I. Fournier, J. Prot Res. (2007), 6 (11), 4127-4134, Specific MALDI Imaging and Profiling for Biomarker Hunting and Validation: Fragment of the 11S Proteasome Activator Complex, Reg Alpha Fragment, Is a New Potential Ovary Cancer Biomarker
  5. [5] J. Stauber, R. Lemaire, J. Franck, D. Bonnel, D. Croix, R. Day, M. Wisztorski, M. Salzet, I. Fournier, J. Prot Res. (2008), 7(3), 969-978,MALDI Imaging of FFPE Tissues: Application to Model Animals of Parkinson Disease for Biomarker Hunting
  6. [6] Franck J., Arafah K., Elayed M., Bonnel D., Vergara D., Jacquet A., Vinatier D., Wisztorski M., Day R., Fournier I., Salzet M., Mol Cell Proteomics (2009) 8(9), 2023-33, MALDI imaging mass spectrometry: state of the art technology in clinical proteomics.
  7. [7] Meriaux C., Arafah K., Tasiemski A., Wisztorski M., Bruand J., Wichlacz-Boidin C., Desmons A., Debois D., Laprévote O., Brunelle A., Gaasterland T., Macagno E., Fournier I., Salzet M., PLos One (2011), 6(4): e18359, Multiple Changes in Peptide and Lipid Expression Associated with Regeneration in the Nervous System of the Medicinal Leech