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Lille 1 University Master Degrees


Lille 1 University Masters


Master of Biology & Biotechnology, Health biology

Functional immunology
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  1. Lesson Plan

  2. Immune response in course of evolution
    - Cellular response in invertebrates
    - Humoral response in invertabrates
    - Adaptative response in course of evolution

  3. Innate Immunity

  4. Neuroimmunology
    - Concept
    - Immune cells express endocrine phenotype
    - Neurons express immune phenotype

  5. Immune response and parasite
    - Chagas disease
    - Malaria disease
    - Schistosoma therapy
    - Zoonoses


Master of Biology & Biotechnology, Genomics & Proteomics

U.E. GP11 P1: Analyzing the Proteome
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GP11 P1 is a fundamental teatching unit based on lectures following:

  1. Extraction and clivages techniques, 4H lectures, Pr. Michel Salzet
  2. Gel electrophoresis, 4H lectures,, Dr. Christophe Tastet
  3. Liquid chromatography, 4H lectures, Pr. Michel Salzet 4-Mass Spectrometry, Lectures 10H and 2H exercices, Pr. Isabelle Fournier

Lecutres outlook

  1. Extraction and clivages techniques (4H)
  1. Liquid Chromatography (4H)
  • Presentation of the various types of LC methods according the nature of interactions and phases
  • Theory and criteria of separation
  • Principles and applications odf RPLC for peptides and proteins separation
  1. Electrophoresis (CM, 6H)
  • Electrochemical principles of SDS-PAGE
  • 2D-Gel electrophoresis: principle and applications
  • BAC ans CTAB PAGE electrophoresis: principle and applications
  • BN PAGE electrophoresis: principle and applications
  1. Mass Spectrometry (12H)
  • Lectures (10H)
    - General introduction to mass spectrometry , applications fields for biomolecule analysis, proteomics strategies
    - Basic notions: short presentation of ion sources and mass analyzor, spectral caracteristics, spectra interpretation
    - Ion production source MALDI & ESI
    - Peptides fragmentations, CID ion activation, fragmentation nomenclature
  • Exercices (2H)
    - Interpretration of ESI and MALDI MS spectra First notions of interpretation of peptides MS/MS spectra